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Strain Registration

Strain: F344-Zeb2em1Kyo

Symbol: F344-Zeb2em1Kyo
Strain: F344-Zeb2em1
Substrain: Kyo
RGD ID: 11040916
Citation ID: RRID:RGD_11040916
Ontology ID: RS:0004121
Also Known As: F344-Zeb2em1Kyo; NBRP Rat No: 0753; F344-Zeb2^[em1Kyo]
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Zinc-finger nucleases (ZFNs) method taregting exon 5 of Zeb2 gene (AGCCAAAGCTTGCCTCCA and GACTACTGACTCAAG) was used; This strain has a 5-bp deletion (cagag) and a 2-bp insertion (tc) in exon7 of Nrf2 gene, resulting in a deletion of Glutamine(Q)541. Background strain: F344/Stm
Coat Color: Albino
Last Known Status: Cryopreserved Sperm
Research Usage Neurobiology; Development






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (Zeb2)
Rat AssemblyChrPosition (strand)Source
GRCr8349,624,028 - 49,754,323 (-)NCBI
mRatBN7.2329,214,581 - 29,344,890 (-)NCBI
mRatBN7.2 Ensembl329,218,301 - 29,345,157 (-)Ensembl
UTH_Rnor_SHR_Utx332,612,891 - 32,735,232 (-)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.0341,197,919 - 41,320,278 (-)NCBI
UTH_Rnor_WKY_Bbb_1.0339,016,630 - 39,138,985 (-)NCBI
Rnor_6.0329,857,289 - 29,985,932 (-)NCBI
Rnor_6.0 Ensembl329,862,473 - 29,996,865 (-)Ensembl
Rnor_5.0335,058,725 - 35,186,767 (-)NCBI
RGSC_v3.4325,513,009 - 25,654,964 (-)NCBI
RGSC_v3.1325,409,380 - 25,556,869 (-)NCBI
Celera327,525,557 - 27,647,939 (-)NCBI
Cytogenetic Map3q12NCBI

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics No abnormalities in gross appearance and behavior. 1302502
strain_reproduction sib mating between homozygous rats. Good breeding performance. 1302502