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Strain Registration

Strain: TRM.W-Tg(RNB1-186G14)33Kyo

Symbol: TRM.W-Tg(RNB1-186G14)33Kyo
Strain: TRM.W-Tg(RNB1-186G14)33
Substrain: Kyo
RGD ID: 11040675
Citation ID: RRID:RGD_11040675
Ontology ID: RS:0004115
Also Known As: NBRP Rat No: 0676; TRM Spata22 Tg Line33
Type: transgenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: F344/Stm rat BAC clone RNB1-186G14 was microinjected into embyos of Wistar rats. The founder rats were backcrossed to TRM/Kyo rats. BAC vector:pKS145. RNB1-186G14 contains region between 60185236-60354841 of Rat Chr 10 and this region contains Spata22 gene expressed in testes.
Coat Color: albino
Inbred Generations: N3F5
Last Known Status: Cryopreserved Sperm






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics TRM rat has a 200-bp deletion including Aspa and Spata22 gene, resulting in leukodystrophy (Aspa defect) and infertility (Spata22 defect). By introduction of RNB1-186G14, infertility phenotype was rescued. 1302502
strain_reproduction maintained by crossing tm/tm homozygous rats 1302502