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Strain Registration

Strain: DA-Tph2em3Mcwi

Symbol: DA-Tph2em3Mcwi
Strain: DA-Tph2em3
Substrain: Mcwi
RGD ID: 10402822
Citation ID: RRID:RGD_10402822
Ontology ID: RS:0004070
Alleles: Tph2em3Mcwi
Also Known As: DA-Tph2em2Mcwi; DA-Tph2em3Mcwi; DA-Tph2^[em3Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CATGGCTCCGACCCCctctacACCCCGGAACCG into DA/OlaHsd rat embryos. The resulting mutation is a 11-bp frameshift deletion in exon 7.
Last Known Status: Cryorecovery (as of 2017-01-26)
Genotyping Protocol Download Genotyping Protocol
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2750,685,694 - 50,789,424RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0758,112,644 - 58,112,654RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0758,053,268 - 58,157,949RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4754,321,033 - 54,430,706RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Tph2em3Mcwi-var1 chr7 58112644 58112654 GGGGTGTAGAG - deletion Rnor_6.0

Additional Information