Strain: BBDP/Rhw

Symbol: BBDP/Rhw
Strain: BBDP
Substrain: Rhw
Ontology ID: RS:0000071
Type: inbred
Source: Not Available
Origin: S. Bieg and coworkers (1998) generated a congenic line in which diabetes and lymphopenia are controlled solely by Iddm 1. This strain was generated by nine cycles of cross-intercross breeding of diabetes-prone DP with DR BB rats. Iddm 1 in the BioBreeding (BB) rat designates the genomic region on rat Chromosome (Chr) 4 that harbors the gene causing peripheral T cell lymphopenia (Lyp) and diabetes. The average age of onset of diabetes was 85 ± 53 days of age after the first and 67 ± 10 days of age after the 9th cycle.





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RGD Object Information
RGD ID: 10002
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2003-04-16
Status: ACTIVE



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