RGD Reference Report - IGF-1 gene polymorphisms in Polish families with high-grade myopia. - Rat Genome Database

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IGF-1 gene polymorphisms in Polish families with high-grade myopia.

Authors: Rydzanicz, M  Nowak, DM  Karolak, JA  Frajdenberg, A  Podfigurna-Musielak, M  Mrugacz, M  Gajecka, M 
Citation: Rydzanicz M, etal., Mol Vis. 2011;17:2428-39. Epub 2011 Sep 21.
RGD ID: 8548829
Pubmed: PMID:21976954   (View Abstract at PubMed)
PMCID: PMC3185023   (View Article at PubMed Central)

PURPOSE: Recent work has suggested that insulin-like growth factor 1 (IGF-1) gene polymorphisms are genetically linked with high-grade myopia (HM), which is a complex-trait eye disorder in which numerous candidate loci and genes are thought to play a role. We investigated whether the IGF-1 single nucleotide polymorphisms (SNPs) rs6214, rs10860860, and rs2946834 are associated with HM (

RGD Manual Disease Annotations    Click to see Annotation Detail View
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
myopia no_associationIAGP 8548829DNA:SNPS: :rs10860860 more ...RGD 
myopia no_associationISOIGF1 (Homo sapiens)8548829; 8548829DNA:SNPS: :rs10860860 more ...RGD 

Objects Annotated

Genes (Rattus norvegicus)
Igf1  (insulin-like growth factor 1)

Genes (Mus musculus)
Igf1  (insulin-like growth factor 1)

Genes (Homo sapiens)
IGF1  (insulin like growth factor 1)


Additional Information