RGD Reference Report - Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit. - Rat Genome Database

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Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit.

Authors: Boulter, J  Evans, K  Goldman, D  Martin, G  Treco, D  Heinemann, S  Patrick, J 
Citation: Boulter J, etal., Nature 1986 Jan 30-Feb 5;319(6052):368-74.
RGD ID: 727609
Pubmed: PMID:3753746   (View Abstract at PubMed)
DOI: DOI:10.1038/319368a0   (Journal Full-text)

We have isolated a complementary DNA clone containing sequences homologous to those encoding the alpha-subunit of a mouse muscle nicotinic acetylcholine receptor. Based on the structural similarities between the encoded protein and the muscle acetylcholine receptor alpha-subunit, and the presence of hybridizing RNA species in the brain, we propose that this clone codes for a neural nicotinic acetylcholine receptor alpha-subunit.

Objects referenced in this article
Gene Chrna3 cholinergic receptor nicotinic alpha 3 subunit Rattus norvegicus

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