RGD Reference Report - High-affinity kainate and domoate receptors in rat brain. - Rat Genome Database

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High-affinity kainate and domoate receptors in rat brain.

Authors: Lomeli, H  Wisden, W  Kohler, M  Keinanen, K  Sommer, B  Seeburg, PH 
Citation: Lomeli H, etal., FEBS Lett 1992 Jul 28;307(2):139-43.
RGD ID: 727533
Pubmed: PMID:1322826   (View Abstract at PubMed)

Mammalian brain expresses receptors which bind the potent neurotoxins, kainate and domoate, with high affinity, and which form a subclass of ionotropic glutamate receptors. A new member of these receptors, expressed in both adult and embryonic CNS is compared in its ligand binding properties to its closely sequence-related homologs.

Gene Ontology Annotations    Click to see Annotation Detail View

Molecular Function
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
glutamate-gated receptor activity enablesIDA 727533; 727533; 727533PMID:1322826UniProt 

Objects Annotated

Genes (Rattus norvegicus)
Grik1  (glutamate ionotropic receptor kainate type subunit 1)
Grik2  (glutamate ionotropic receptor kainate type subunit 2)
Grik3  (glutamate ionotropic receptor kainate type subunit 3)

Objects referenced in this article
Gene Grik5 glutamate ionotropic receptor kainate type subunit 5 Rattus norvegicus

Additional Information