RGD Reference Report - [Drug therapy of shock]. - Rat Genome Database

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[Drug therapy of shock].

Authors: Bartels, O  Junge, O  Topf, G 
Citation: Bartels O, etal., Fortschr Med. 1978 Mar 30;96(12):653-60.
RGD ID: 631810
Pubmed: PMID:631705   (View Abstract at PubMed)

Shock is to define by clinical symptoms, measurable haemodynamic and metabolic changes, clotting failure and disorders of fluid, electrolyte and acid-base balance. It is essential to remove hypovolemia, acidosis, cardiovascular failure, pulmonary and renal insufficiency. Quite a lot of proved and controversial pharmacological substances are placed at physician's disposal. However, the mortality of cardiogenic shock and gram-negative septic shock is more than 80% respectively 30%, often caused by shock lung or irreversible injury to the kidneys. Shock due to depletion of extracellular fluid, poisoning and acute pancreatitis require specific treatment.

Objects referenced in this article
Gene Adora3 adenosine A3 receptor Rattus norvegicus

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