RGD Reference Report - LRRK2 R1398H polymorphism is associated with decreased risk of Parkinson's disease in a Han Chinese population. - Rat Genome Database

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LRRK2 R1398H polymorphism is associated with decreased risk of Parkinson's disease in a Han Chinese population.

Authors: Chen, L  Zhang, S  Liu, Y  Hong, H  Wang, H  Zheng, Y  Zhou, H  Chen, J  Xian, W  He, Y  Li, J  Liu, Z  Pei, Z  Zeng, J 
Citation: Chen L, etal., Parkinsonism Relat Disord. 2011 May;17(4):291-2. Epub 2010 Dec 14.
RGD ID: 5508409
Pubmed: PMID:21159540   (View Abstract at PubMed)
DOI: DOI:10.1016/j.parkreldis.2010.11.012   (Journal Full-text)

Abstract for this paper unavailable

RGD Manual Disease Annotations    Click to see Annotation Detail View
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Parkinson's disease susceptibilityIAGP 5508409DNA:missense mutation:cds:p.R1398H (human)RGD 
Parkinson's disease susceptibilityISOLRRK2 (Homo sapiens)5508409; 5508409DNA:missense mutation:cds:p.R1398H (human)RGD 

Phenotype Annotations    Click to see Annotation Detail View

Manual Human Phenotype Annotations - RGD

TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Bradykinesia susceptibilityIAGP 5508409DNA:missense mutation:cds:p.R1398HRGD 
Parkinsonism susceptibilityIAGP 5508409DNA:missense mutation:cds:p.R1398HRGD 
Objects Annotated

Genes (Rattus norvegicus)
Lrrk2  (leucine-rich repeat kinase 2)

Genes (Mus musculus)
Lrrk2  (leucine-rich repeat kinase 2)

Genes (Homo sapiens)
LRRK2  (leucine rich repeat kinase 2)


Additional Information