RGD Reference Report - Safety and efficacy of beta agonists. - Rat Genome Database

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Safety and efficacy of beta agonists.

Authors: Donohue, JF 
Citation: Donohue JF Respir Care. 2008 May;53(5):618-22; discussion 623-4.
RGD ID: 4140444
Pubmed: PMID:18426615   (View Abstract at PubMed)

Both short-acting and long-acting beta agonists have been used for many years for the treatment of asthma. Short-acting beta agonists are life-saving and their role as rescue agents is unquestioned, but regular use is not recommended because of safety concerns and the effectiveness of asthma-controller medications. Long-acting beta agonists are effective controller medications but have safety issues, so their use should be restricted to patients who are not optimally controlled on first-line controllers such as inhaled corticosteroids. The effect of the beta receptor genotype on beta agonist response is unclear but could hold promise for proper patient management.

Molecular Pathway Annotations    Click to see Annotation Detail View

RGD Manual Annotations

Objects Annotated

Genes (Rattus norvegicus)
Adrb2  (adrenoceptor beta 2)

Genes (Mus musculus)
Adrb2  (adrenergic receptor, beta 2)

Genes (Homo sapiens)
ADRB2  (adrenoceptor beta 2)


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