RGD Reference Report - Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia. - Rat Genome Database

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Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia.

Authors: Hebbring, SJ  Slager, SL  Epperla, N  Mazza, JJ  Ye, Z  Zhou, Z  Achenbach, SJ  Vasco, DA  Call, TG  Rabe, KG  Kay, NE  Caporaso, NE  Lanasa, MC  Camp, NJ  Strom, SS  Goldin, LR  Cerhan, JR  Brilliant, MH  Schrodi, SJ 
Citation: Hebbring SJ, etal., Blood. 2013 Jan 3;121(1):237-8. doi: 10.1182/blood-2012-08-450221.
RGD ID: 11533998
Pubmed: PMID:23287625   (View Abstract at PubMed)
PMCID: PMC5091216   (View Article at PubMed Central)
DOI: DOI:10.1182/blood-2012-08-450221   (Journal Full-text)

Abstract for this paper unavailable

RGD Manual Disease Annotations    Click to see Annotation Detail View
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
chronic lymphocytic leukemia susceptibilityIAGP 11533998DNA:snp:cds:p.R620W (rs2476601) (human)RGD 
chronic lymphocytic leukemia susceptibilityISOPTPN22 (Homo sapiens)11533998; 11533998DNA:snp:cds:p.R620W (rs2476601) (human)RGD 

Phenotype Annotations    Click to see Annotation Detail View

Manual Human Phenotype Annotations - RGD

TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Abnormal B cell morphology  IAGP 11533998DNA:snp:cds:p.R620W (rs2476601)RGD 
Objects Annotated

Genes (Rattus norvegicus)
Ptpn22  (protein tyrosine phosphatase, non-receptor type 22)

Genes (Mus musculus)
Ptpn22  (protein tyrosine phosphatase, non-receptor type 22 (lymphoid))

Genes (Homo sapiens)
PTPN22  (protein tyrosine phosphatase non-receptor type 22)


Additional Information