MAMTS4_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: MAMTS4_H (Mammary tumor susceptibility QTL 4 (human)) Homo sapiens

Symbol: MAMTS4_H
Name: Mammary tumor susceptibility QTL 4 (human)
RGD ID: 2302765
Trait: Mammary tumor susceptibility
LOD Score: Not Available
P Value: 0.044
Variance: Not Available
Position No map positions available.
Cross Type: Not Available
Population Stats: Eastern Finnish population



Candidate Gene Status
TMPRSS6 is a candidate Gene for MAMTS4_H

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Refinement of the 22q12-q13 breast cancer--associated region: evidence of TMPRSS6 as a candidate gene in an eastern Finnish population. Hartikainen JM, etal., Clin Cancer Res. 2006 Mar 1;12(5):1454-62.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D22S1177)
Human AssemblyChrPosition (strand)Source
Marshfield Genetic Map2242.81RGD
Marshfield Genetic Map2242.81UniSTS
Genethon Genetic Map2238.3UniSTS
deCODE Assembly Map2243.51UniSTS
Flank 2: (Il2rb)
Human AssemblyChrPosition (strand)Source
GRCr87111,913,828 - 111,928,537 (-)NCBI
mRatBN7.27110,033,341 - 110,048,054 (-)NCBI
mRatBN7.2 Ensembl7110,033,341 - 110,048,054 (-)Ensembl
UTH_Rnor_SHR_Utx7111,783,773 - 111,798,546 (-)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.07114,007,308 - 114,022,077 (-)NCBI
UTH_Rnor_WKY_Bbb_1.07113,975,130 - 113,989,824 (-)NCBI
Rnor_6.07119,701,338 - 119,716,238 (-)NCBI
Rnor_6.0 Ensembl7119,701,251 - 119,716,238 (-)Ensembl
Rnor_5.07119,690,375 - 119,705,275 (-)NCBI
Celera7106,371,243 - 106,385,925 (-)NCBI
Cytogenetic Map7q34NCBI


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general Odds ratio for heterozygote (T/C) was 1.39, 95% CI 1.06-1.83 2301994
qtl_population Eastern Finnish population 2301994
qtl_population_details 497 breast cancer cases, 458 controls 2301994
qtl_statistics_details Software used: SPSS v 11.5, Fisher's exact test and Monte Carlo approximation 2301994