Fut7 (fucosyltransferase 7) - Rat Genome Database

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Gene: Fut7 (fucosyltransferase 7) Rattus norvegicus
Analyze
Symbol: Fut7
Name: fucosyltransferase 7
RGD ID: 735019
Description: Enables alpha-(1->3)-fucosyltransferase activity. Involved in inflammatory response. Predicted to be located in trans-Golgi network. Orthologous to human FUT7 (fucosyltransferase 7); PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway; O-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha (1,3) fucosyltransferase; alpha (13) fucosyltransferase; alpha-(1,3)-fucosyltransferase; alpha-(1,3)-fucosyltransferase 7; Fuc-TVII; fucosyltransferase 7 (alpha (1,3) fucosyltransferase); fucosyltransferase VII; FucT-VII; galactoside 3-L-fucosyltransferase; selectin ligand synthase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,635,913 - 28,640,407 (+)NCBIGRCr8
mRatBN7.238,237,687 - 8,242,273 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,239,384 - 8,242,260 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx311,344,499 - 11,347,371 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,930,721 - 19,933,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,120,569 - 18,123,441 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,637,281 - 2,646,497 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,642,531 - 2,646,648 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,623,653 - 2,628,513 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,590,174 - 3,593,046 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,590,173 - 3,593,045 (+)NCBI
Celera33,064,494 - 3,067,366 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Cloning and expression of rat fucosyltransferase VII at sites of inflammation. Niittymäki J, etal., APMIS. 2005 Sep;113(9):613-20. doi: 10.1111/j.1600-0463.2005.apm_279.x.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Expression of the alpha(1,3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands. Smith PL, etal., J Biol Chem 1996 Apr 5;271(14):8250-9.
Additional References at PubMed
PMID:8207002   PMID:8666674   PMID:8752218   PMID:9299472   PMID:9405391   PMID:9461592   PMID:9473504   PMID:10200296   PMID:10386892   PMID:10894166   PMID:11278338   PMID:11404359  
PMID:11535629   PMID:15843584   PMID:15926890   PMID:17229154   PMID:18402946   PMID:18553500   PMID:18573908   PMID:19946888   PMID:23192350   PMID:29138114  


Genomics

Comparative Map Data
Fut7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,635,913 - 28,640,407 (+)NCBIGRCr8
mRatBN7.238,237,687 - 8,242,273 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,239,384 - 8,242,260 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx311,344,499 - 11,347,371 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,930,721 - 19,933,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,120,569 - 18,123,441 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,637,281 - 2,646,497 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,642,531 - 2,646,648 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,623,653 - 2,628,513 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,590,174 - 3,593,046 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,590,173 - 3,593,045 (+)NCBI
Celera33,064,494 - 3,067,366 (+)NCBICelera
Cytogenetic Map3p13NCBI
FUT7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,030,174 - 137,032,088 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,030,174 - 137,032,088 (-)EnsemblGRCh38hg38GRCh38
GRCh379139,924,626 - 139,926,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,044,447 - 139,047,283 (-)NCBINCBI36Build 36hg18NCBI36
Build 349137,200,462 - 137,203,299NCBI
Cytogenetic Map9q34.3NCBI
HuRef9109,383,478 - 109,386,144 (-)NCBIHuRef
CHM1_19140,073,389 - 140,076,055 (-)NCBICHM1_1
T2T-CHM13v2.09149,264,609 - 149,266,523 (-)NCBIT2T-CHM13v2.0
Fut7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,312,363 - 25,316,386 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,313,279 - 25,316,386 (+)EnsemblGRCm39 Ensembl
GRCm38225,422,351 - 25,426,374 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,423,267 - 25,426,374 (+)EnsemblGRCm38mm10GRCm38
MGSCv37225,279,214 - 25,281,894 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,245,293 - 25,248,380 (+)NCBIMGSCv36mm8
Celera225,151,205 - 25,153,885 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.25NCBI
Fut7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555135,056,718 - 5,061,974 (-)NCBIChiLan1.0ChiLan1.0
FUT7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,365,825 - 2,368,648 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,368,178 - 2,370,890 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,090,793 - 108,093,513 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,058,831 - 137,061,607 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,058,831 - 137,061,607 (-)Ensemblpanpan1.1panPan2
FUT7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,604,879 - 48,609,292 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,606,435 - 48,609,303 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,821,203 - 47,822,270 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,483,176 - 49,487,261 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,485,443 - 49,487,254 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,261,839 - 48,262,906 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,560,576 - 48,561,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,607,910 - 48,608,977 (+)NCBIUU_Cfam_GSD_1.0
Fut7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,448,245 - 202,456,791 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669919,206 - 920,341 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936669914,520 - 920,481 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FUT7
(Sus scrofa - pig)
No map positions available.
FUT7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,158,353 - 1,160,913 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660584,141,161 - 4,143,999 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fut7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624760876,059 - 877,574 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624760876,048 - 877,984 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fut7
9 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:302
Count of miRNA genes:194
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000037169
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat

Markers in Region
UniSTS:224625  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.238,241,868 - 8,242,111 (+)MAPPERmRatBN7.2
Rnor_6.032,646,095 - 2,646,337NCBIRnor6.0
Rnor_5.032,627,508 - 2,627,750UniSTSRnor5.0
RGSC_v3.433,592,653 - 3,592,895UniSTSRGSC3.4
Celera33,066,973 - 3,067,215UniSTS
Cytogenetic Map3p13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 1 34 26 19 26 22 15 11
Below cutoff 1 33 23 15 15 4 6 52 31 26 4

Sequence


RefSeq Acc Id: ENSRNOT00000037169   ⟹   ENSRNOP00000033858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl38,239,384 - 8,242,260 (+)Ensembl
Rnor_6.0 Ensembl32,643,610 - 2,646,486 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000081798   ⟹   ENSRNOP00000069960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl32,642,531 - 2,646,648 (+)Ensembl
RefSeq Acc Id: NM_199491   ⟹   NP_955785
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,637,535 - 28,640,407 (+)NCBI
mRatBN7.238,239,390 - 8,242,262 (+)NCBI
Rnor_6.032,643,616 - 2,646,488 (+)NCBI
Rnor_5.032,623,653 - 2,628,513 (+)NCBI
RGSC_v3.433,590,174 - 3,593,046 (+)RGD
Celera33,064,494 - 3,067,366 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233585   ⟹   XP_006233647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,636,577 - 28,640,407 (+)NCBI
mRatBN7.238,238,422 - 8,242,273 (+)NCBI
Rnor_6.032,642,611 - 2,646,497 (+)NCBI
Rnor_5.032,623,653 - 2,628,513 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233586   ⟹   XP_006233648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,636,581 - 28,640,407 (+)NCBI
mRatBN7.238,238,427 - 8,242,273 (+)NCBI
Rnor_6.032,642,611 - 2,646,497 (+)NCBI
Rnor_5.032,623,653 - 2,628,513 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233587   ⟹   XP_006233649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,635,913 - 28,640,407 (+)NCBI
mRatBN7.238,237,687 - 8,242,273 (+)NCBI
Rnor_6.032,642,462 - 2,646,497 (+)NCBI
Rnor_5.032,623,653 - 2,628,513 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104714   ⟹   XP_038960642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,636,585 - 28,640,407 (+)NCBI
mRatBN7.238,239,073 - 8,242,273 (+)NCBI
RefSeq Acc Id: XM_039104715   ⟹   XP_038960643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,636,583 - 28,640,407 (+)NCBI
mRatBN7.238,238,428 - 8,242,273 (+)NCBI
RefSeq Acc Id: NP_955785   ⟸   NM_199491
- UniProtKB: Q712G6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233649   ⟸   XM_006233587
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006233647   ⟸   XM_006233585
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006233648   ⟸   XM_006233586
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000069960   ⟸   ENSRNOT00000081798
RefSeq Acc Id: ENSRNOP00000033858   ⟸   ENSRNOT00000037169
RefSeq Acc Id: XP_038960643   ⟸   XM_039104715
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960642   ⟸   XM_039104714
- Peptide Label: isoform X3
- UniProtKB: A6JT59 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q712G6-F1-model_v2 AlphaFold Q712G6 1-370 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735019 AgrOrtholog
BioCyc Gene G2FUF-50454 BioCyc
BioCyc Pathway PWY-7831 [ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide] BioCyc
BioCyc Pathway Image PWY-7831 BioCyc
Ensembl Genes ENSRNOG00000014156 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055000510 UniProtKB/Swiss-Prot
  ENSRNOG00060023400 UniProtKB/Swiss-Prot
  ENSRNOG00065025335 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000037169 ENTREZGENE
  ENSRNOT00000037169.5 UniProtKB/Swiss-Prot
  ENSRNOT00055000883 UniProtKB/Swiss-Prot
  ENSRNOT00060040549 UniProtKB/Swiss-Prot
  ENSRNOT00065043659 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.11660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glyco_tran_10_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_trans_10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GT10-like_C_sf UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
KEGG Report rno:296564 UniProtKB/Swiss-Prot
NCBI Gene 296564 ENTREZGENE
PANTHER ALPHA- 1,3 -FUCOSYLTRANSFERASE UniProtKB/TrEMBL
  ALPHA-(1,3)-FUCOSYLTRANSFERASE 7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11929 UniProtKB/Swiss-Prot
Pfam Glyco_tran_10_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_transf_10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fut7 PhenoGen
RatGTEx ENSRNOG00000014156 RatGTEx
  ENSRNOG00055000510 RatGTEx
  ENSRNOG00060023400 RatGTEx
  ENSRNOG00065025335 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6JT59 ENTREZGENE, UniProtKB/TrEMBL
  FUT7_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Fut7  fucosyltransferase 7  Fut7  fucosyltransferase 7 (alpha (1,3) fucosyltransferase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Fut7  fucosyltransferase 7 (alpha (1,3) fucosyltransferase)  Fut7  fucosyltransferase 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Fut7  fucosyltransferase 7  fut7  fucosyltransferase VII  Symbol and Name updated 1299863 APPROVED