Ppargc1b (PPARG coactivator 1 beta)

Gene: Ppargc1b (PPARG coactivator 1 beta) Rattus norvegicus

Analyze

Symbol:

Ppargc1b

Name:

PPARG coactivator 1 beta

RGD ID:

727948

Description:

Predicted to enable AF-2 domain binding activity; nuclear estrogen receptor binding activity; and nuclear receptor coactivator activity. Involved in response to cAMP; response to glucocorticoid; and response to nutrient. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of mediator complex. Predicted to be active in nucleus. Biomarker of metabolic dysfunction-associated steatotic liver disease. Human ortholog(s) of this gene implicated in obesity. Orthologous to human PPARGC1B (PPARG coactivator 1 beta); INTERACTS WITH (R)-lipoic acid; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Perc; peroxisome proliferative activated receptor, gamma, coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma coactivator 1beta-2a; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; PGC-1-beta; PGC1beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	57,029,264 - 57,131,466 (-)	NCBI		GRCr8
mRatBN7.2	18	54,758,891 - 54,861,103 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	54,758,902 - 54,861,194 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	56,852,399 - 56,954,689 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	57,567,002 - 57,669,290 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	55,382,768 - 55,484,982 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	56,626,725 - 56,650,524 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	56,626,712 - 56,728,968 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	55,857,439 - 55,880,661 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	57,277,749 - 57,301,024 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	57,349,991 - 57,451,796 (-)	NCBI
Celera	18	52,911,177 - 52,934,708 (-)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis (ISO)

Breast Neoplasms (ISO)

COVID-19 (ISO)

familial adenomatous polyposis 1 (ISO)

familial hyperlipidemia (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Hypertriglyceridemia (IEP)

Insulin Resistance (IEP,ISO)

metabolic dysfunction-associated steatotic liver disease (IEP)

Neurodevelopmental Disorders (ISO)

obesity (ISO)

Sepsis (IEP)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(R)-lipoic acid (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP)

amiodarone (ISO)

ammonium chloride (EXP)

angiotensin II (EXP)

arsane (ISO)

arsenic atom (ISO)

atorvastatin calcium (EXP,ISO)

atrazine (EXP)

belinostat (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

cadmium atom (EXP)

cadmium dichloride (EXP)

carbon nanotube (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

colforsin daropate hydrochloride (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

diclofenac (ISO)

diethyl maleate (EXP)

dioxygen (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

duvoglustat (ISO)

endosulfan (EXP)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

etoposide (ISO)

formaldehyde (ISO)

FR900359 (ISO)

genistein (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

Ile(5)-angiotensin II (EXP)

isoprenaline (ISO)

ketoconazole (EXP)

linoleic acid (EXP)

lipoic acid (EXP)

lipopolysaccharide (ISO)

meldonium (EXP)

menadione (ISO)

methimazole (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-acetyl-L-cysteine (EXP)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP,ISO)

oxaloacetic acid (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phosphatidylcholine (ISO)

phosphatidylethanolamine (ISO)

phytol (ISO)

phytosterols (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

quercetin (EXP,ISO)

resveratrol (EXP)

rotenone (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sulforaphane (ISO)

sunitinib (ISO)

T-2 toxin (EXP)

tamoxifen (ISO)

testosterone enanthate (EXP)

tetrachloromethane (ISO)

thioacetamide (EXP)

trans-piceid (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

Triptolide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

tunicamycin (ISO)

valproic acid (ISO)

very-low-density lipoprotein triglyceride (ISO)

vinclozolin (EXP)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament organization (IEA,ISO)

bone trabecula formation (IEA,ISO)

cellular response to reactive oxygen species (IEA,ISO)

intracellular estrogen receptor signaling pathway (IEA,ISO,ISS)

mitochondrial transcription (IEA,ISO)

negative regulation of DNA-templated transcription (IEA,ISO)

ossification (IEA,ISO)

positive regulation of bone resorption (IEA,ISO)

positive regulation of cold-induced thermogenesis (IEA,ISO,ISS)

positive regulation of DNA-templated transcription (ISO)

positive regulation of osteoclast differentiation (IEA,ISO)

positive regulation of phosphorylation (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IBA,IEA,ISO,ISS)

regulation of DNA-templated transcription (ISO,ISS)

response to cAMP (IEP)

response to glucocorticoid (IEP)

response to nutrient (IEP)

Cellular Component

cytosol (IEA,ISO)

mediator complex (IEA,ISO)

mitochondrion (IEA)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO,ISS)

Molecular Function

AF-2 domain binding (IEA,ISO,ISS)

nuclear estrogen receptor binding (IEA,ISO)

nuclear receptor coactivator activity (IBA,IEA,ISO,ISS)

protein binding (ISO)

RNA binding (IEA)

transcription coregulator activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity.	Andersen G, etal., J Med Genet. 2005 May;42(5):402-7.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Peroxisome proliferator-activated receptor-gamma coactivator-1 and insulin resistance: acute effect of fatty acids.	Hoeks J, etal., Diabetologia. 2006 Oct;49(10):2419-26. Epub 2006 Aug 1.
4.	Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.	Lelliott CJ, etal., PLoS Biol. 2006 Nov;4(11):e369. doi: 10.1371/journal.pbio.0040369.
5.	PGC-1beta in the regulation of hepatic glucose and energy metabolism.	Lin J, etal., J Biol Chem. 2003 Aug 15;278(33):30843-8. Epub 2003 Jun 13.
6.	Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle.	Menconi MJ, etal., Am J Physiol Endocrinol Metab. 2010 Oct;299(4):E533-43. Epub 2010 Jul 20.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
9.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
10.	Putative association of peroxisome proliferator-activated receptor gamma co-activator 1beta (PPARGC1B) polymorphism with Type 2 diabetes mellitus.	Park KS, etal., Diabet Med. 2006 Jun;23(6):635-42.
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Comprehensive gene review and curation	RGD comprehensive gene curation
14.	Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis.	Zhang H, etal., PLoS One. 2015 Sep 22;10(9):e0138203. doi: 10.1371/journal.pone.0138203. eCollection 2015.

Additional References at PubMed

PMID:11854298	PMID:12678921	PMID:15057822	PMID:17932310	PMID:19252502	PMID:19254570	PMID:19542216	PMID:21331471	PMID:22008020	PMID:23264620	PMID:23836911	PMID:27631411
PMID:30635067

Genomics

Comparative Map Data

Ppargc1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	57,029,264 - 57,131,466 (-)	NCBI		GRCr8
mRatBN7.2	18	54,758,891 - 54,861,103 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	54,758,902 - 54,861,194 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	56,852,399 - 56,954,689 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	57,567,002 - 57,669,290 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	55,382,768 - 55,484,982 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	56,626,725 - 56,650,524 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	56,626,712 - 56,728,968 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	55,857,439 - 55,880,661 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	57,277,749 - 57,301,024 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	57,349,991 - 57,451,796 (-)	NCBI
Celera	18	52,911,177 - 52,934,708 (-)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

PPARGC1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	149,730,310 - 149,857,959 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	149,730,298 - 149,855,022 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	149,109,873 - 149,234,585 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	149,090,057 - 149,207,474 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	149,090,056 - 149,207,460	NCBI
Celera	5	145,191,258 - 145,315,947 (+)	NCBI		Celera
Cytogenetic Map	5	q32	NCBI
HuRef	5	144,256,984 - 144,381,544 (+)	NCBI		HuRef
CHM1_1	5	148,542,243 - 148,667,243 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	150,266,870 - 150,394,600 (+)	NCBI		T2T-CHM13v2.0

Ppargc1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	61,424,516 - 61,533,846 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	61,431,207 - 61,533,502 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	61,291,445 - 61,400,756 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	61,298,136 - 61,400,431 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	61,457,790 - 61,560,085 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	61,423,505 - 61,525,800 (-)	NCBI		MGSCv36	mm8
Celera	18	62,581,981 - 62,683,996 (-)	NCBI		Celera
Cytogenetic Map	18	E1	NCBI
cM Map	18	34.41	NCBI

Ppargc1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	4,644,998 - 4,757,093 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	4,638,057 - 4,756,885 (-)	NCBI	ChiLan1.0	ChiLan1.0

PPARGC1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	144,955,386 - 145,119,813 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	143,098,132 - 143,223,525 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	145,154,517 - 145,315,567 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	151,172,020 - 151,286,285 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	151,203,088 - 151,278,837 (+)	Ensembl	panpan1.1		panPan2

PPARGC1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	59,167,041 - 59,278,977 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	59,174,604 - 59,279,464 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	58,935,873 - 59,044,751 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	59,651,179 - 59,761,207 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	59,651,182 - 59,761,176 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	59,439,467 - 59,548,290 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	59,553,927 - 59,662,788 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	60,085,118 - 60,194,024 (-)	NCBI		UU_Cfam_GSD_1.0

Ppargc1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	143,518,121 - 143,624,571 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936504	5,099,470 - 5,198,584 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936504	5,099,334 - 5,198,279 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPARGC1B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	150,823,373 - 150,919,376 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	150,823,338 - 150,924,871 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	157,649,522 - 157,739,519 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPARGC1B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	52,337,802 - 52,462,553 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	52,428,052 - 52,455,089 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	25,255,708 - 25,379,965 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppargc1b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	9,056,322 - 9,174,388 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624774	9,056,138 - 9,178,645 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ppargc1b
447 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	176
Count of miRNA genes:	78
Interacting mature miRNAs:	83
Transcripts:	ENSRNOT00000023661, ENSRNOT00000066048
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25570985	70570985	Rat
2293704	Bss35	Bone structure and strength QTL 35	4.59	0.0002	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	18	28964853	73964853	Rat
2300157	Bmd66	Bone mineral density QTL 66	13.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
2300177	Bmd65	Bone mineral density QTL 65	19.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	29792965	74792965	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	29792965	74792965	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	29792965	74792965	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	29792965	74792965	Rat
738005	Anxrr11	Anxiety related response QTL 11	3.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	18	30039813	75039813	Rat
61383	Bp47	Blood pressure QTL 47	17.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	31271681	60377755	Rat
1331742	Bp228	Blood pressure QTL 228	3.88752		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
1331774	Bp226	Blood pressure QTL 226	4.41065		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
1331776	Bp225	Blood pressure QTL 225	2.829		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	31359408	59796643	Rat
1331798	Bp224	Blood pressure QTL 224	3.53873		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
1331727	Bp237	Blood pressure QTL 237	3.053		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	61698465	Rat
61429	Cia17	Collagen induced arthritis QTL 17	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	31359408	70263868	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31359408	83218561	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359530	59796478	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31393320	77209694	Rat
631518	Bw11	Body weight QTL 11	2.8		body mass (VT:0001259)	body weight (CMO:0000012)	18	35870723	80870723	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	38192455	83192455	Rat
1598826	Anxrr20	Anxiety related response QTL 20	3.04		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	18	41432971	83828827	Rat
6893683	Bw110	Body weight QTL 110	2.7	0.002	body mass (VT:0001259)	body weight (CMO:0000012)	18	43345022	83828827	Rat
8694366	Abfw8	Abdominal fat weight QTL 8	6.38	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	18	46640675	83828827	Rat
8694432	Bw165	Body weight QTL 165	3.81	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	46640675	83828827	Rat
9589041	Epfw12	Epididymal fat weight QTL 12	17.08	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	18	46640675	83828827	Rat
1331806	Bp229	Blood pressure QTL 229	4.36484		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	46718763	57867167	Rat
1331736	Bp227	Blood pressure QTL 227	2.791		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	46718763	59796643	Rat
1331780	Bp238	Blood pressure QTL 238	3.269		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	46718763	59796643	Rat
6903345	Bp349	Blood pressure QTL 349	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	46718935	59796478	Rat
6903349	Bp351	Blood pressure QTL 351	3.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	46718935	59796478	Rat
6903351	Bp352	Blood pressure QTL 352	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	46718935	59796478	Rat
61360	Eaey	Experimental allergic encephalomyelitis QTL y	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	18	46988939	60377753	Rat
2303571	Bw92	Body weight QTL 92	3		body mass (VT:0001259)	body weight (CMO:0000012)	18	48520044	83828827	Rat
2303584	Gluco55	Glucose level QTL 55	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	18	48520044	83828827	Rat
7411719	Strs5	Sensitivity to stroke QTL 5	9.4		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	18	49999958	65845095	Rat
2293658	Bmd23	Bone mineral density QTL 23	7.3	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	18	51464733	63636873	Rat
738008	Hcar14	Hepatocarcinoma resistance QTL 14	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion number (CMO:0001462)	18	51464733	83218561	Rat
1331730	Scl27	Serum cholesterol level QTL 27	3.826		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	52292875	59796643	Rat
1331752	Bw27	Body weight QTL 27	2.963		body mass (VT:0001259)	body weight (CMO:0000012)	18	52292875	65845095	Rat
1359020	Ppulsi2	Prepulse inhibition QTL 2	2.71		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	18	52292875	73997283	Rat
1600375	Mcs22	Mammary carcinoma susceptibility QTL 22	3.3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	52539763	63933058	Rat
631509	Sald2	Serum aldosterone level QTL 2	2.9		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	18	52539763	69140759	Rat
12880368	Bw187	Body weight QTL 187		0.045	body mass (VT:0001259)	body weight (CMO:0000012)	18	52539763	76104388	Rat
12904067	Cm122	Cardiac mass QTL 122		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	52539763	76104388	Rat
12904069	Cm123	Cardiac mass QTL 123		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	52539763	76104388	Rat
12904070	Cm124	Cardiac mass QTL 124		0.01	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	52539763	76104388	Rat
12904071	Am18	Aortic mass QTL 18		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	52539763	76104388	Rat
12904073	Kidm71	Kidney mass QTL 71		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	52539763	76104388	Rat
2301417	Bp319	Blood pressure QTL 319		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	52539763	76104388	Rat
1300125	Rf26	Renal function QTL 26	3.2		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	18	52539863	65844950	Rat
1298072	Cia26	Collagen induced arthritis QTL 26	3.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	54709769	83828827	Rat

Markers in Region

D18Chm35

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	54,780,558 - 54,780,754 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	56,648,393 - 56,648,590	NCBI	Rnor6.0
Rnor_5.0	18	55,878,530 - 55,878,727	UniSTS	Rnor5.0
RGSC_v3.4	18	57,298,893 - 57,299,090	UniSTS	RGSC3.4
Celera	18	52,932,504 - 52,932,774	UniSTS
Cytogenetic Map	18	q12.1	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		28	4		2		1	1	6	1	8		1
Low	3	15	53	41	17	41	7	10	68	34	33	11	7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_176075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY188951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000023661 ⟹ ENSRNOP00000023661

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	54,758,902 - 54,861,194 (-)	Ensembl
Rnor_6.0 Ensembl	18	56,626,712 - 56,728,968 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000066048 ⟹ ENSRNOP00000058932

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	54,758,902 - 54,861,039 (-)	Ensembl
Rnor_6.0 Ensembl	18	56,626,736 - 56,728,185 (-)	Ensembl

RefSeq Acc Id:

NM_176075 ⟹ NP_788264

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	57,029,264 - 57,131,466 (-)	NCBI
mRatBN7.2	18	54,758,891 - 54,861,103 (-)	NCBI
Rnor_6.0	18	56,626,725 - 56,650,524 (-)	NCBI
Rnor_5.0	18	55,857,439 - 55,880,661 (-)	NCBI
RGSC_v3.4	18	57,277,749 - 57,301,024 (-)	RGD
Celera	18	52,911,177 - 52,934,708 (-)	RGD

Sequence:

show sequence

ATGCAGGGGGAAGGGAAGGGTGGGGAGTCTGGAGAGGAACAGTTATGTGCTGACTTGCCAGAGC
TCGACCTCTCCCAGCTGGATGCCAGTGACTTCGACTCAGCCACGTGCTTTGGGGAGCTGCAGTG
GTGCCCGGAGACCTCAGAGACAGAGCCCAGCCAGTACAGCCCTGATGATTCCGAGTTCTTCCAG
ATTGACAGTGAGAATGAAGCTCTCTTGGCTGCGCTTACCAAGACCCTGGATGACATCCCCGAAG
ACGATGTGGGGCTGGCTGCCTTCCCAGGACTGGATGAAGGCGACACACCCTCCTGCACCCCAGC
TTCACCTGCTCCTTTATCTGTGCCCCCCAGCCCCGCCTTGGAGAGGCTTCTGTCCCCAGTGTCT
GAAGTGGATGAGCTTTCACTGCTGCAGAAGCTCCTCCTGGCCACATCCTCCCCAACAGCAAGCT
CTGATGCTCTGAAGGACGGGGCCACCTGGTCGCAGACCAGCCTCAGTTCCAGAAGTCAGCGGCC
TTGTGTCAAGGTGGATGGCACCCAGGACAAGAAGACCCCCATGCTACGGTCTCAGAGCCGGCCT
TGTACAGAACTGCATAAGCACCTCACTTCGGTGCTGCCCTGCCCCAGGGGAAAAGCCTGTTCCC
CACCTCCCCACCCAAGTCCTCAGCTCCTCTCCAAAGAGGATGAGGAGGTGGGAGAGGATTGCCC
AAGCCCCTGGCCAGCTCCAGCGTCTCCCCAAGACTCACTAGGACAGGACACGGCCAACCCCAAC
AGTGCCCAAGTTCCCAAGGACGACGTGAGGGCCATGGTACAGCTCATTCGCTACATGCATACCT
ACTGCCTGCCTCAGAGGAAGCTGCCCCAACGGGCCTCAGAGCCAATCCCCCAGTCCTGCAGCAG
CCCCTTGAGGAAGGTCCCACCCCGATCCCGGCAAACCCCCAAAGCCTTCTGGACTGAGTTCTCC
ATCCTAAGGGAACTTCTGGCCCAAGATATCCTCTGTGATGTTAGCAAGCCCTACCGCCTGGCCA
CACCTGTCTATGCTTCTCTCACACCCCAGTCCAGAACCAGGCCCCCCAAAGACAGTCAGGCCTC
CCCTGCCCACTCTGCCATGGCAGAAGAGGTGAGAATCACTGCTTCCCCCAAGAGCACTGGACCT
AGACCCAGCCTCCGTCCTCTGAGGCTAGAGGTGAAACGGGATGTCAACAAGCCTGCAAGGCAAA
AGCGGGAGGAAGATGAGGAGGAGGAAGAGGAAGAAGAAGAGGAAGAAGAAAAAGAGGATGAAGA
AGAGGAGTGGGGCAGGAAGAGACCAGGTCGTGGCCTGCCATGGACCAAACTAGGGAGGAAGATG
GACAGCTCTGTGTGCCCTGTGCGGCGCTCCAGGAGACTGAATCCAGAGCTGGGCCCTTGGCTGA
CATTCACTGATGAGCCCCTAGGTGCTCTACCCTCGATGTGCCTGGCTACAGAGACCCACGACCT
GGAAGAAGAGCTGGGCGGCCTCACAGACAGTAGTCAAGGCCAGCAGCTCCCCCTGGGATCCCAG
ATCCCCACCCTGGAAAGCCCCTGTGAAAGTGGGTGTGGGGACACAGATGAAGATCCAAGCTGCC
CGCGGCCCCCTTCCAGAGACTCCCCCAGGTGCCTCATGCTGGCCTTGTCACAAAGTGACCCTCT
TGGCAAGAAGAGCTTTGAGGAGTCCTTGACAGTGGAGCTTTGTGGCACAGCAGGACTCACTCCA
CCCACCACACCTCCATATAAGCCCATGGAGGAGGACCCCTTCAAGCAGGACACCAAGCACAGCC
CAGGCCAAGACACAGCTCCCAGCCTCCCTTCCCCTGAGACTCTTCAGCTCACAGCCACCCCAGG
GGCTTCCCACAAGCTGCCCAAGAGGCACCCGGAGCGAAGTGAGCTCCTGTCTCATCTGCAACAT
GCCACAACCCAGCCAGTCTCACAGGCTGGCCAGAAGCGTCCCTTCTCCTGCTCCTTTGGAGACC
ATGACTACTGCCAGGTGATCAGGCCAGAGGCTGCCCTGCAGAGGAAGGTGCTGCGGTCCTGGGA
GCCAATCAAGGTCCACCTTGAAGACTTGGCCCACCAGGGTGCAACCCTGCCAGTGGAAACAAAG
ACCCCTAGGAGGGAGGCAGACCAGAACTGTGACCCCACCCCCAAGGACAGCATGCAGCTAAGAG
ACCATGAGATCCGTGCCAGCCTCACAAAGCACTTTGGGCTGCTGGAAACCGCTCTGGAGGAGGA
AGACTTGGCTTCATGTAAAAGCCCGGAGTATGACACCGTATTTGAGGACAGCAGCAGCAGCAGT
GGCGAGAGCAGCTTCCTGCTAGAGGAGGAGGAAGAGGAGGGAGGGGAAGAGGACGATGAAGGAG
AGGACTCAGGGGTCAGCCCTCCCTGCTCCGACCACTGCCCCTACCAGAGCCCACCCAGTAAGGC
CAGTCGGCAGCTCTGTTCCCGAAGCCGCTCCAGTTCTGGCTCCTCATCCTGTAGCTCCTGGTCA
CCAGCTACCCGGAAGAACTTCAGACTTGAGAGCAGAGGGCCCTGTTCAGATGGAACCCCAAGCG
CCCGGCATGCCAAGAAGCGGCGGGAAAAGGCCATCGGTGAAGGTCGTGTGGTATACATCCGAAA
TCTCTCCGGTGACATGAGCTCTCGAGAACTAAAGAAGCGCTTCGAGGTGTTTGGTGAGATAGTC
GAGTGCCAGGTGCTGAGGAGAAGTAAGAGAGGCCAGAAGCACGGTTTTATTACCTTCCGGTGTT
CGGAGCATGCCGCCCTGTCCGTGAGGAACGGCGCTACCCTGAGAAAACGCAATGAGCCCTCCTT
CCACCTGAGCTATGGAGGGCTCCGGCACTTCCGCTGGCCCAGATACACCGACTATGATCCCACG
TCTGAAGAGTCCCTTCCCTCGTCTGGGAAAAGCAAGTACGAAGCCATGGATTTTGACAGCTTAC
TGAAAGAGGCCCAGCAGAGCCTGCATTAATATCAGCCTTAACCTTCGAGGAATACCTCAATACC
TCAGACAAGGCCCTTCCAATATGTTTACGTTTTCAAAGAAATGAGTATATGAGGAGGAGAGCAA
GCCAATGAGCGAGCGAGCGAGCGAGCGTGAGAGAACACACAGGAGAGAGAGACTTGAATCTGCT
GTCGTTTCCTTTAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_788264	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAO40026	(Get FASTA)	NCBI Sequence Viewer
	EDM14598	(Get FASTA)	NCBI Sequence Viewer
	EDM14599	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000023661
	ENSRNOP00000023661.3
	ENSRNOP00000058932.4
	ENSRNOP00055019420
	ENSRNOP00060035782
	ENSRNOP00065029432
GenBank Protein	Q811R2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_788264 ⟸ NM_176075

- UniProtKB:

Q811R2 (UniProtKB/Swiss-Prot), A6IXG7 (UniProtKB/TrEMBL), A0A8L2QTA8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQGEGKGGESGEEQLCADLPELDLSQLDASDFDSATCFGELQWCPETSETEPSQYSPDDSEFFQ
IDSENEALLAALTKTLDDIPEDDVGLAAFPGLDEGDTPSCTPASPAPLSVPPSPALERLLSPVS
EVDELSLLQKLLLATSSPTASSDALKDGATWSQTSLSSRSQRPCVKVDGTQDKKTPMLRSQSRP
CTELHKHLTSVLPCPRGKACSPPPHPSPQLLSKEDEEVGEDCPSPWPAPASPQDSLGQDTANPN
SAQVPKDDVRAMVQLIRYMHTYCLPQRKLPQRASEPIPQSCSSPLRKVPPRSRQTPKAFWTEFS
ILRELLAQDILCDVSKPYRLATPVYASLTPQSRTRPPKDSQASPAHSAMAEEVRITASPKSTGP
RPSLRPLRLEVKRDVNKPARQKREEDEEEEEEEEEEEEKEDEEEEWGRKRPGRGLPWTKLGRKM
DSSVCPVRRSRRLNPELGPWLTFTDEPLGALPSMCLATETHDLEEELGGLTDSSQGQQLPLGSQ
IPTLESPCESGCGDTDEDPSCPRPPSRDSPRCLMLALSQSDPLGKKSFEESLTVELCGTAGLTP
PTTPPYKPMEEDPFKQDTKHSPGQDTAPSLPSPETLQLTATPGASHKLPKRHPERSELLSHLQH
ATTQPVSQAGQKRPFSCSFGDHDYCQVIRPEAALQRKVLRSWEPIKVHLEDLAHQGATLPVETK
TPRREADQNCDPTPKDSMQLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSS
GESSFLLEEEEEEGGEEDDEGEDSGVSPPCSDHCPYQSPPSKASRQLCSRSRSSSGSSSCSSWS
PATRKNFRLESRGPCSDGTPSARHAKKRREKAIGEGRVVYIRNLSGDMSSRELKKRFEVFGEIV
ECQVLRRSKRGQKHGFITFRCSEHAALSVRNGATLRKRNEPSFHLSYGGLRHFRWPRYTDYDPT
SEESLPSSGKSKYEAMDFDSLLKEAQQSLH

hide sequence

RefSeq Acc Id:

ENSRNOP00000023661 ⟸ ENSRNOT00000023661

RefSeq Acc Id:

ENSRNOP00000058932 ⟸ ENSRNOT00000066048

Protein Domains

RRM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q811R2-F1-model_v2	AlphaFold	Q811R2	1-1010	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727948	AgrOrtholog
BioCyc Gene	G2FUF-7334	BioCyc
Ensembl Genes	ENSRNOG00000017503	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055013837	UniProtKB/Swiss-Prot
	ENSRNOG00060024864	UniProtKB/Swiss-Prot
	ENSRNOG00065021452	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000023661	ENTREZGENE
	ENSRNOT00000023661.6	UniProtKB/Swiss-Prot
	ENSRNOT00000066048.4	UniProtKB/TrEMBL
	ENSRNOT00055023820	UniProtKB/Swiss-Prot
	ENSRNOT00060043223	UniProtKB/Swiss-Prot
	ENSRNOT00065036526	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.70.330	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Nucleotide-bd_a/b_plait_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PGC-1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PPARGC1B_RRM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RRM_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:291567	UniProtKB/Swiss-Prot
NCBI Gene	291567	ENTREZGENE
PANTHER	PTHR15528	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR15528:SF12	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ppargc1b	PhenoGen
PROSITE	RRM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017503	RatGTEx
	ENSRNOG00055013837	RatGTEx
	ENSRNOG00060024864	RatGTEx
	ENSRNOG00065021452	RatGTEx
SMART	RRM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2QTA8	ENTREZGENE, UniProtKB/TrEMBL
	A6IXG7	ENTREZGENE, UniProtKB/TrEMBL
	A6IXG8_RAT	UniProtKB/TrEMBL
	PRGC2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-03	Ppargc1b	PPARG coactivator 1 beta	Ppargc1b	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	Ppargc1b	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta			Symbol and Name updated	1299863	APPROVED
2004-02-11	Il1rapl1	peroxisome proliferator-activated receptor gamma coactivator 1 beta	Perc	peroxisome proliferator-activated receptor gamma coactivator 1beta-2a	Name updated to reflect Human and Mouse nomenclature	625702	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

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