Serpina4 (serpin family A member 4) - Rat Genome Database

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Gene: Serpina4 (serpin family A member 4) Rattus norvegicus
Analyze
Symbol: Serpina4
Name: serpin family A member 4
RGD ID: 708581
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be active in extracellular space. Orthologous to human SERPINA4 (serpin family A member 4); PARTICIPATES IN kallikrein-kinin cascade pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kallistatin; LOC246328; MGC108582; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; sserpin family A member 4
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,764,738 - 128,773,858 (+)NCBIGRCr8
mRatBN7.26122,999,970 - 123,009,083 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,999,900 - 123,009,082 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6123,140,853 - 123,150,010 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06123,436,147 - 123,445,304 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,772,949 - 122,782,107 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,743,883 - 127,753,047 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,743,971 - 127,753,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06136,962,809 - 136,972,495 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46128,133,692 - 128,142,768 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16128,137,438 - 128,146,514 (+)NCBI
Celera6120,479,942 - 120,489,009 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dichloroacetic acid  (ISO)
flutamide  (EXP)
fulvestrant  (ISO)
furan  (EXP)
GW 4064  (ISO)
L-ethionine  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
omeprazole  (EXP)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
propiconazole  (ISO)
quercetin  (ISO)
rifampicin  (ISO)
ritodrine  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
sulfasalazine  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trichloroethene  (ISO)
troglitazone  (ISO)
urethane  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coli. Chai KX, etal., J Biol Chem 1993 Nov 15;268(32):24498-505.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Kallistatin in human ocular tissues: reduced levels in vitreous fluids from patients with diabetic retinopathy. Ma JX, etal., Curr Eye Res. 1996 Nov;15(11):1117-23.
4. The kallikrein-kinin system: current and future pharmacological targets. Moreau ME, etal., J Pharmacol Sci. 2005 Sep;99(1):6-38.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19056867   PMID:20551380   PMID:23376485   PMID:23533145   PMID:27068509   PMID:37682567  


Genomics

Comparative Map Data
Serpina4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,764,738 - 128,773,858 (+)NCBIGRCr8
mRatBN7.26122,999,970 - 123,009,083 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,999,900 - 123,009,082 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6123,140,853 - 123,150,010 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06123,436,147 - 123,445,304 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,772,949 - 122,782,107 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,743,883 - 127,753,047 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,743,971 - 127,753,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06136,962,809 - 136,972,495 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46128,133,692 - 128,142,768 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16128,137,438 - 128,146,514 (+)NCBI
Celera6120,479,942 - 120,489,009 (+)NCBICelera
Cytogenetic Map6q32NCBI
SERPINA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381494,561,442 - 94,569,906 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1494,561,442 - 94,569,913 (+)EnsemblGRCh38hg38GRCh38
GRCh371495,027,779 - 95,036,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361494,097,536 - 94,105,996 (+)NCBINCBI36Build 36hg18NCBI36
Build 341494,097,535 - 94,105,994NCBI
Celera1475,083,955 - 75,092,415 (+)NCBICelera
Cytogenetic Map14q32.13NCBI
HuRef1475,208,201 - 75,216,660 (+)NCBIHuRef
CHM1_11494,965,577 - 94,974,035 (+)NCBICHM1_1
T2T-CHM13v2.01488,791,396 - 88,799,857 (+)NCBIT2T-CHM13v2.0
Serpina4-ps1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912104,044,218 - 104,053,179 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12104,046,908 - 104,052,983 (+)EnsemblGRCm39 Ensembl
GRCm3812104,077,959 - 104,086,920 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12104,080,649 - 104,086,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712105,316,169 - 105,325,130 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612104,479,014 - 104,487,970 (+)NCBIMGSCv36mm8
Celera12105,296,260 - 105,305,223 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1253.23NCBI
SERPINA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21595,710,635 - 95,719,094 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11494,927,140 - 94,935,599 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01475,185,501 - 75,194,061 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11494,517,341 - 94,525,820 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1494,517,341 - 94,525,820 (+)Ensemblpanpan1.1panPan2
SERPINA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1863,552,033 - 63,560,667 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl863,552,107 - 63,560,667 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha863,128,761 - 63,137,404 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0863,819,080 - 63,827,728 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl863,819,165 - 63,827,728 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1863,494,328 - 63,502,965 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0863,546,668 - 63,555,306 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0863,877,345 - 63,885,985 (+)NCBIUU_Cfam_GSD_1.0
LOC100157117
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7115,783,931 - 115,792,466 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17115,781,772 - 115,792,469 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27122,899,948 - 122,909,065 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SERPINA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12472,345,566 - 72,356,257 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2472,347,261 - 72,356,416 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605359,569,833 - 59,577,130 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Serpina4
80 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:143
Count of miRNA genes:108
Interacting mature miRNAs:121
Transcripts:ENSRNOT00000013045
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2 2 2
Medium 35 35 35 1
Low 2 10 4 2 4 5 5 3 4 4 6 5
Below cutoff 6 10 15 3 3 8 19 16 2 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000013045   ⟹   ENSRNOP00000013045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6122,999,937 - 123,009,082 (+)Ensembl
Rnor_6.0 Ensembl6127,743,971 - 127,753,046 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113429   ⟹   ENSRNOP00000084751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6122,999,900 - 123,009,082 (+)Ensembl
RefSeq Acc Id: NM_145097   ⟹   NP_659565
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,764,782 - 128,773,858 (+)NCBI
mRatBN7.26123,000,007 - 123,009,083 (+)NCBI
Rnor_6.06127,743,971 - 127,753,047 (+)NCBI
Rnor_5.06136,962,809 - 136,972,495 (+)NCBI
RGSC_v3.46128,133,692 - 128,142,768 (+)RGD
Celera6120,479,942 - 120,489,009 (+)RGD
Sequence:
RefSeq Acc Id: XM_008764741   ⟹   XP_008762963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,764,738 - 128,773,858 (+)NCBI
mRatBN7.26122,999,970 - 123,009,083 (+)NCBI
Rnor_6.06127,743,883 - 127,753,047 (+)NCBI
Sequence:
RefSeq Acc Id: NP_659565   ⟸   NM_145097
- Peptide Label: precursor
- UniProtKB: Q5M8C3 (UniProtKB/TrEMBL),   F6Q5J8 (UniProtKB/TrEMBL),   P97569 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762963   ⟸   XM_008764741
- Peptide Label: isoform X1
- UniProtKB: Q5M8C3 (UniProtKB/TrEMBL),   F6Q5J8 (UniProtKB/TrEMBL),   P97569 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013045   ⟸   ENSRNOT00000013045
RefSeq Acc Id: ENSRNOP00000084751   ⟸   ENSRNOT00000113429
Protein Domains
SERPIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M8C3-F1-model_v2 AlphaFold Q5M8C3 1-423 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694802
Promoter ID:EPDNEW_R5327
Type:multiple initiation site
Name:Serpina4_1
Description:serpin family A member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06127,743,958 - 127,744,018EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708581 AgrOrtholog
BioCyc Gene G2FUF-36394 BioCyc
Ensembl Genes ENSRNOG00000009788 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013045 ENTREZGENE
  ENSRNOT00000013045.7 UniProtKB/TrEMBL
  ENSRNOT00000113429.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
  Serpins superfamily UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368874 IMAGE-MGC_LOAD
InterPro Protease_inhib_I4_serpin UniProtKB/TrEMBL
  Protease_inhib_I4_serpin_CS UniProtKB/TrEMBL
  Sepin_dom UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
KEGG Report rno:246328 UniProtKB/TrEMBL
MGC_CLONE MGC:108582 IMAGE-MGC_LOAD
NCBI Gene 246328 ENTREZGENE
PANTHER KALLISTATIN UniProtKB/TrEMBL
  Prot_inh_serpin UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PhenoGen Serpina4 PhenoGen
PROSITE SERPIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009788 RatGTEx
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP Prot_inh_serpin UniProtKB/TrEMBL
UniProt A0A8I5ZZZ2_RAT UniProtKB/TrEMBL
  A6JEQ2_RAT UniProtKB/TrEMBL
  F6Q5J8 ENTREZGENE, UniProtKB/TrEMBL
  P97569 ENTREZGENE, UniProtKB/TrEMBL
  Q5M8C3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-20 Serpina4  serpin family A member 4  Serpina4  sserpin family A member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-13 Serpina4  sserpin family A member 4  Serpina4  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-01 Serpina4  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4  Serpina4  serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Serpina4  serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4  LOC246328  kallistatin  Symbol and Name updated 1299863 APPROVED