Brinp3 (BMP/retinoic acid inducible neural specific 3)

Gene: Brinp3 (BMP/retinoic acid inducible neural specific 3) Rattus norvegicus

Analyze

Symbol:

Brinp3

Name:

BMP/retinoic acid inducible neural specific 3

RGD ID:

708421

Description:

Involved in negative regulation of cell cycle and nervous system development. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human BRINP3 (BMP/retinoic acid inducible neural specific 3); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

BMP/retinoic acid-inducible neural-specific protein 3; bone morphogenetic protein/retinoic acid inducible neural-specific 3; Fam5c; family with sequence similarity 5, member C

RGD Orthologs

Alliance Genes

More Info

more info ...

Allele / Splice:

Brinp3^{Tn(sb-T2/Bart3)2.189Mcwi}

Genetic Models:

F344-Brinp3^{Tn(sb-T2/Bart3)2.189Mcwi}

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	60,964,127 - 61,397,044 (+)	NCBI		GRCr8
mRatBN7.2	13	58,413,883 - 58,846,828 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	58,413,883 - 58,846,770 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	61,020,501 - 61,453,226 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	62,233,620 - 62,668,293 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	59,535,895 - 59,969,267 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	63,526,486 - 63,959,390 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	63,526,486 - 63,959,332 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	68,507,826 - 68,938,032 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	60,584,348 - 61,024,196 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	60,598,427 - 61,038,280 (+)	NCBI
Celera	13	58,457,115 - 58,885,779 (+)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aggressive periodontitis (ISO)

cerebral infarction (ISO)

Chronic Periodontitis (ISO)

coronary artery disease (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

myocardial infarction (ISO)

parathyroid carcinoma (ISO)

Peri-Implantitis (ISO)

periodontal disease (ISO)

tongue squamous cell carcinoma (ISO)

ulcerative colitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium dichloride (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

doxorubicin (ISO)

fenvalerate (EXP)

genistein (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

paracetamol (ISO)

PCB138 (ISO)

perfluorononanoic acid (ISO)

permethrin (EXP)

pirinixic acid (ISO)

pyrethrins (EXP)

resveratrol (ISO)

rotenone (ISO)

stigmasterol (ISO)

sulforaphane (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (EXP)

trimellitic anhydride (ISO)

triptonide (ISO)

valproic acid (ISO)

venlafaxine hydrochloride (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to retinoic acid (IBA,ISO,ISS)

central nervous system neuron differentiation (ISO,ISS)

negative regulation of cell cycle (IMP)

negative regulation of mitotic cell cycle (IBA,ISO,ISS)

nervous system development (IBA,IEP)

positive regulation of neuron differentiation (IEA)

Cellular Component

cytoplasm (IBA)

dendrite (IBA,IDA)

extracellular region (IEA)

mitochondrion (IEA)

neuronal cell body (IBA,IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	FAM5C contributes to aggressive periodontitis.	Carvalho FM, etal., PLoS One. 2010 Apr 7;5(4):e10053. doi: 10.1371/journal.pone.0010053.
2.	Different contribution of BRINP3 gene in chronic periodontitis and peri-implantitis: a cross-sectional study.	Casado PL, etal., BMC Oral Health. 2015 Mar 11;15:33. doi: 10.1186/s12903-015-0018-6.
3.	Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease.	Chen X, etal., Hum Genomics. 2016 Jul 25;10 Suppl 2:21. doi: 10.1186/s40246-016-0067-1.
4.	Genetic and functional association of FAM5C with myocardial infarction.	Connelly JJ, etal., BMC Med Genet. 2008 Apr 22;9:33. doi: 10.1186/1471-2350-9-33.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Identification and characterization of novel developmentally regulated neural-specific proteins, BRINP family.	Kawano H, etal., Brain Res Mol Brain Res 2004 Jun 18;125(1-2):60-75.
7.	Expression of the FAM5C in tongue squamous cell carcinoma.	Kuroiwa T, etal., Oncol Rep. 2009 Nov;22(5):1005-11.
8.	The Expression of microRNA-223 and FAM5C in Cerebral Infarction Patients with Diabetes Mellitus.	Long Y, etal., Cardiovasc Toxicol. 2017 Jan;17(1):42-48. doi: 10.1007/s12012-015-9354-7.
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Comprehensive gene review and curation	RGD comprehensive gene curation
12.	Mucosal transcriptomics implicates under expression of BRINP3 in the pathogenesis of ulcerative colitis.	Smith PJ, etal., Inflamm Bowel Dis. 2014 Oct;20(10):1802-12. doi: 10.1097/MIB.0000000000000169.

Additional References at PubMed

PMID:20025061

Genomics

Comparative Map Data

Brinp3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	60,964,127 - 61,397,044 (+)	NCBI		GRCr8
mRatBN7.2	13	58,413,883 - 58,846,828 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	58,413,883 - 58,846,770 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	61,020,501 - 61,453,226 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	62,233,620 - 62,668,293 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	59,535,895 - 59,969,267 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	63,526,486 - 63,959,390 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	63,526,486 - 63,959,332 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	68,507,826 - 68,938,032 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	60,584,348 - 61,024,196 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	60,598,427 - 61,038,280 (+)	NCBI
Celera	13	58,457,115 - 58,885,779 (+)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

BRINP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	190,097,658 - 190,477,864 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	190,097,658 - 190,478,404 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	190,066,788 - 190,446,994 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	188,333,420 - 188,713,382 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	163,175,438 - 163,555,389 (-)	NCBI		Celera
Cytogenetic Map	1	q31.1	NCBI
HuRef	1	161,301,488 - 161,681,433 (-)	NCBI		HuRef
CHM1_1	1	191,488,894 - 191,868,789 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	189,444,081 - 189,824,968 (-)	NCBI		T2T-CHM13v2.0

Brinp3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	146,371,367 - 146,778,210 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	146,370,498 - 146,778,210 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	146,495,629 - 146,902,472 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	146,494,760 - 146,902,472 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	148,342,796 - 148,749,602 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	148,257,908 - 148,664,596 (+)	NCBI		MGSCv36	mm8
Celera	1	148,998,933 - 149,401,562 (+)	NCBI		Celera
Cytogenetic Map	1	F	NCBI
cM Map	1	63.24	NCBI

Brinp3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	27,869,456 - 28,238,978 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	27,870,115 - 28,240,328 (-)	NCBI	ChiLan1.0	ChiLan1.0

BRINP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	59,281,767 - 59,667,440 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	58,957,363 - 59,349,809 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	165,586,510 - 165,972,173 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	169,873,182 - 170,258,838 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	169,873,541 - 170,258,015 (-)	Ensembl	panpan1.1		panPan2

BRINP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	8,181,227 - 8,558,518 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	8,205,916 - 8,558,482 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	8,274,323 - 8,651,253 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	8,208,155 - 8,585,823 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	8,207,162 - 8,589,938 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	8,211,135 - 8,588,313 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	8,572,447 - 8,950,586 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	8,809,824 - 9,186,801 (+)	NCBI		UU_Cfam_GSD_1.0

Brinp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	82,864,573 - 83,220,448 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936481	713,539 - 1,068,237 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936481	711,356 - 1,067,856 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BRINP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	2,963,527 - 3,367,623 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	2,963,237 - 3,367,629 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	4,783,341 - 5,184,626 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BRINP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	38,950,219 - 39,340,920 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	39,147,423 - 39,340,564 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	39,964,726 - 40,359,521 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Brinp3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624814	3,094,109 - 3,502,857 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624814	3,092,139 - 3,502,625 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Brinp3
5694 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	206
Count of miRNA genes:	144
Interacting mature miRNAs:	162
Transcripts:	ENSRNOT00000003788
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	14915655	59915655	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	15158722	60158722	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	22301875	67301875	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	23203448	68203448	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	23692969	68692969	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	23692969	68692969	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	32284471	77284471	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	34535218	79535218	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	37262092	82262092	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	37415584	80753406	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	37415584	82415584	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	38433408	83433408	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39754544	84754544	Rat
6893344	Cm79	Cardiac mass QTL 79	1.5	0.04	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	43720770	62022792	Rat
12879444	Bp397	Blood pressure QTL 397			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45049404	90049404	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45514719	90514719	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45699983	90699983	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	46088046	91088046	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	46197976	84753113	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
2303028	Bp329	Blood pressure QTL 329			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	58497872	73485113	Rat

Markers in Region

D13Rat179

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	58,497,872 - 58,498,119 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	63,611,283 - 63,611,529	NCBI	Rnor6.0
Rnor_5.0	13	68,591,963 - 68,592,209	UniSTS	Rnor5.0
RGSC_v3.4	13	60,669,451 - 60,669,696	RGD	RGSC3.4
RGSC_v3.4	13	60,669,450 - 60,669,696	UniSTS	RGSC3.4
RGSC_v3.1	13	60,683,531 - 60,683,776	RGD
Celera	13	58,541,101 - 58,541,347	UniSTS
SHRSP x BN Map	13	22.7299	RGD
SHRSP x BN Map	13	22.7299	UniSTS
Cytogenetic Map	13	q21	UniSTS

Genetic Models

This gene Brinp3 is modified in the following models/strains:

F344-Brinp3^{Tn(sb-T2/Bart3)2.189Mcwi}

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									46
Low	1								22	14	18
Below cutoff	2	2	9	2	6	2	3	4	6	15	16	4	3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_173121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB077854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000003788 ⟹ ENSRNOP00000003788

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	58,413,883 - 58,846,770 (+)	Ensembl
Rnor_6.0 Ensembl	13	63,526,486 - 63,959,332 (+)	Ensembl

RefSeq Acc Id:

NM_173121 ⟹ NP_775144

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	60,964,127 - 61,396,985 (+)	NCBI
mRatBN7.2	13	58,413,883 - 58,846,766 (+)	NCBI
Rnor_6.0	13	63,526,486 - 63,959,328 (+)	NCBI
Rnor_5.0	13	68,507,826 - 68,938,032 (+)	NCBI
RGSC_v3.4	13	60,584,348 - 61,024,196 (+)	RGD
Celera	13	58,457,115 - 58,885,779 (+)	RGD

Sequence:

show sequence

CTTTCACCTCTCTTTGCAGATCTGTTTGTCTTATCCATCCCGTTCTCTTGGGTTACTCAGCTTC
TGCCTTTTCTCACTGTGTGGGGACGTGCAGTTAAGTAAATTTGTTCGCCTGAGGACCATAATAG
GAAAGGTTCCCACGGTTACCCATTCTCAGTTAAAAAAAAAAAAAAGCACTTTAACATTTTTGCC
TCCTTTACTTTTGGGTTCTTGGCCCCTTCAGTAAGTGGCTTTCACTTGATTAGATGCCACCAGG
AACTACTGGGTGTTTCCAACTCCTAGTGTCCTGCAGCTTACAAATCTACACTGCTCTGGAAGAT
CATGGGATGTCTCCTTGAATTGTGGATGTATTTCTCTTACAGTCATCTGGCTTCATTGAGTTTC
CTCCGGTGTTGAAGGAAAGCTGAGAGGATGAAGGCTCTAAGTCCCCAGTGGAAGCATGATATGG
CGGCGCAGAGCTGGTGCTGAATTGTCCTCTCTGATGGCTCTATGGGAGTGGATAGTACTGAGTC
TTCATTGCTGGGTTTTAGCGGTTGCTGCTGTCTCTGACCAGCATGCCACAAGCCCCTTCGACTG
GCTCCTCTCTGATAAGGGACCCTTCCATCGCTCACAGGAGTACACAGATTTTGTGGACAGAAGC
CGACAGGGATTTAGCACAAGATACAAGATATACAGGGAGTTTGGCCGTTGGAAGGTAAATAACC
TTGCAGTTGAGAGAAGAAATTTCCTTGGCTCTCCTCTGCCTCTTGCCCCTGAATTCTTCCGCAA
TATAAGGCTTTTGGGACGACGACCTACACTTCAGCAAATCACAGAAAATCTTATCAAGAAATAT
GGGACTCATTTCTTGCTATCAGCTACTCTGGGAGGAGAGGAGTCACTCACAATTTTTGTGGACA
AGCGGAAGCTGAGCAAACGACCAGAAGGAAGTGAAACCAGCACCAATAGTTCGTCTGTCACCCT
TGAGACACTACATCAATTGGCTGCTTCCTATTTTATTGACAGGGACAGCACCCTTCGCAGGCTT
CACCATATCCAAATTGCATCTACTGCCATCAAGGTGACAGAAACACGGACGGGTCCTCTTGGCT
GCAGTAACTATGACAACCTAGATTCTGTCAGCTCTGTCTTGGTTCAGAGTCCAGAGAATAAAAT
TCAGTTGCAAGGGCTTCAAGTTCTCCTTCCCGACTACCTTCAGGAACGTTTTGTACAGGCAGCG
TTGAGCTACATTGCTTGTAATTCTGAGGGGGAGTTTATCTGCAAGGAGAATGACTGCTGGTGCC
TCTGTGGTCCAAAATTCCCAGAATGCAATTGCCCCTCCATGGATATTCAAGCCATGGAAGAGAA
TCTTCTTCGAATAACTGAAACATGGAAAGCCTACAACAGTGACTTTGAAGATTCAGATGAATTC
AAGTTCTTTATGAAAAGACTACCCATGAATTATTTCCTCAACACTTCAACTATAATGCATTTGT
GGACAATGGATTCTAATTTTCAGCGCCGCTATGAACAACTAGAGAACAGCATGAAGCAGCTTTT
CCTGAAGGCACATAGAATTGTACACAAGCTCTTTAGCCTTAGCAAACGGTGCCACAAGCAGCCT
CTCATCAGCCTGCCAAGACAGAGAACTTCAACCTACTGGCTCACTCGCATCCAGTCTTTTCTCT
ACTGCAATGAAAATGGCCTTCTGGGTAGCTTCTCCGAGGAAACCCATTCCTGCACATGCCCCAA
CGACCAGGTAGTGTGCACAGCCTTTCTGCCCTGTACCGTGGGCGATGCCTCGGCCTGCCTGACC
TGTGCACCTGACAATCGCACCCGCTGTGGCACCTGCAACACAGGTTACATGCTGAGCCAGGGAC
TCTGCAAGCCTGAAGTCGCTGAGTCAACAGATCATTACATTGGCTTTGAGACCGACCTGCAAGA
CCTGGAGATGAAATACCTGTTGCAGAAAACAGACAGACGAATAGAAGTCCACGCCATCTTTATC
AGTAATGACATGCGCCTCAACAGCTGGTTTGATCCTTCCTGGAGAAAGAGGATGCTCCTGACCT
TGAAGAGTAACAAGTACAAGTCCAGTCTGGTCCACATGATCTTAGGTCTGTCTTTACAGATTTG
CTTAACTAAAAACAGCACGTTGGAGCCAGTGCTGGCTGTTTACATCAATCCCTTTGGAGGCAGC
CACTCCGAGAGCTGGTTTATGCCTGTGAGCGAGAGCAGCTTTCCAGACTGGGAGCGGACTAAAT
TGGACCTTCCACTGCAGTGCTATAACTGGACACTGACTCTGGGAAACAAATGGAAGACATTCTT
TGAGACAGTACACATCTACCTGAGGAGTCGCATCAAAGCAAATGGCCCCAACAGCAATGAGAGC
ATTTACTACGAGCCTTTGGAGTTTATTGACCCATCCCGGAACCTGGGCTACATGAAAATCAACA
ACATCCAAGTGTTTGGCTACAGCATGCACTTTGACCCAGAAGCCATTCGGGACCTGATTTTGCA
GCTGGACTACCCCTACACTCAGGGATCCCAGGACTCGGCACTTTTGCAACTACTAGAGATAAGA
GACCGTGTAAATAAACTCTCCCCACCTGGTCAGCGACGCCTGGATCTGTTTTCTTGCTTGCTTC
GTCATAGACTCAAGTTGTCTACTAGTGAGGTGGTGAGAATTCAATCTGCTCTTCAGGCATTTAA
TGCCAAGTTGCCAAACACAGTGGATTATGACACAACCAAATTATGTAGTTAACCTTAAATGTCA
AGCACAACCCAAAATCTTGGAGGAGTTTTTACAGTGCTTTTGTGGAAGTTTATGTTTGGAAAAG
TAAATTTAAATTGTCTTTTCAATATCTGTCTTATATCAGTCAATAACGTTGGATGGCAATTTAC
ACACATGAACTTGCTGACAATGAATATATTATACTACAGTTTTGGTTTATGAATGAAATAAATA
CTGACACCAGTCTAGAAGACATTCTACTTTTTACAATAAATTTCATTTGTAATTTTATATGTTC
CGTGGCAATGCTTTTGTGCTATTACATCTCT

hide sequence

RefSeq Acc Id:

XM_017598680 ⟹ XP_017454169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	60,965,664 - 61,397,044 (+)	NCBI
mRatBN7.2	13	58,415,414 - 58,846,828 (+)	NCBI
Rnor_6.0	13	63,527,192 - 63,959,390 (+)	NCBI

Sequence:

show sequence

AGTTACTTTCAGATTGCAAATACCTATGTGTGTGACCATTGGTACATGCTGTAACTAGTAAGAT
GTAGCCTGTAAAATAACGTGCCCCAATACTTCCTTAAAAAATAAAGAAAAAAGAAAATCCCCAA
CTATATACAAGTTTCTATCAGGTAATGTGGACATTACCTCCCAATAATGTACCCCTCCTGGAAC
ACAGCATAGTATCATTTGAAGAGGTATTTTTTTCTATTACTCTATGAAAATGCTTCAAGGAGAG
CTATTTCTGAAGGAGAACTGGTTATTTATGGGTTTGGGAAAGTTCACTAGTCTCAGTGACGTTC
AGAAGCTGGTCCAGGTCAGCATGTGTTCATCCCATCCTAAACAACTGAATGGTTGAGGGAGGAC
TTTGGTTAAGTGTGTCTATTGATTTAGTAGGATCCTAAATACTATCATCGCACTCTATGACAAG
GAAGAAGAGTCCGAGTTTTGAGGGCATCGTTCTTTATACCATATCCAAATTGTACCTGGGCACA
TTATTTTGGTCATCGTGGTTCCTGTCTGGGCAGCATTTTGCAATGCATTTAGGTTTTGTGAATT
ATGCTGGGAACAGTTAATTGGTCAGGGAGGTCTCCCTTCAGATGAAGAGAGCTATCAGAAGCCA
CTGATTATCTGGGTTCTAATACATTGAAATTCAGGGAGGGACTTTACATGAAAAATGTAATTGC
CTCTCTCTTCACACTTGCCCACCCCTGCCCTCAGTTTTTAATAAGTATGTTAATATGCTCGCTG
TGTTGGGCTTTTATGAACATTTCTATGGGCTTTAACTGATGATCCTTCTCATTCCACCGAGTTG
CTTTGAGGATCATTTAAATGTTGGATTTTACTTTACATATGGCCAAGAGTTTGGTAATTACCAA
TCACAAACATGCACACGTCCATAATCTGTAAAGCACAAAATTTTGCCCAATCTCCCTTTACTTG
GGTGGATGGAGATGAGGATATATTGTTCAAGCTTCTCCTTCCTAAGTTATTTTTAAGGGGGGGG
TGTTCTTTTTAATTTCTGGGAAAGAACTGTTCCAGTCATTGATGGCTGACGCGACAATCTAGGC
AATGATTTCTTTCTTTTTAATTCAAAAGCCTTTAAAGCTTCCAGACATAAAAGTACTCCAGCTG
CAGCATCGCACCATCCCCCTCCCCCGACTCAGATTCCAGGGCTTTCCCCCTTGCTTCCCACCGA
GTAGGAGAGGAATTGGGGCTCACACAGTGATCTGCACCTCTTGGCGTCCCTCACCCAGCGCTAG
TCTACCTGCTGCCTTTGCCAGTTCGGTCCGTCCTGCCTGAGAAGCCAGGGCCATTAGCGTCCGT
GACTTCATTTGAAGAAAAGAGGCTTTGGTGTAATTCGCCAATTCAAATACCCTCTCTAGAGGAC
TACTGCTGTTGCGCAGGGGTGGAGGGAGAGAGAGAGAGGAAGGAGAAAACTTTCAGTGCAGTCA
GACCTTTTTCTGCTTAATCAGTGTGACACAGTGAGGCACAGACGTTCGCTGTCTAGGTGTTGAA
GGAAAGCTGAGAGGATGAAGGCTCTAAGTCCCCAGTGGAAGCATGATATGGCGGCGCAGAGCTG
GTGCTGAATTGTCCTCTCTGATGGCTCTATGGGAGTGGATAGTACTGAGTCTTCATTGCTGGGT
TTTAGCGGTTGCTGCTGTCTCTGACCAGCATGCCACAAGCCCCTTCGACTGGCTCCTCTCTGAT
AAGGGACCCTTCCATCGCTCACAGGAGTACACAGATTTTGTGGACAGAAGCCGACAGGGATTTA
GCACAAGATACAAGATATACAGGGAGTTTGGCCGTTGGAAGGTAAATAACCTTGCAGTTGAGAG
AAGAAATTTCCTTGGCTCTCCTCTGCCTCTTGCCCCTGAATTCTTCCGCAATATAAGGCTTTTG
GGACGACGACCTACACTTCAGCAAATCACAGAAAATCTTATCAAGAAATATGGGACTCATTTCT
TGCTATCAGCTACTCTGGGAGGAGAGGAGTCACTCACAATTTTTGTGGACAAGCGGAAGCTGAG
CAAACGACCAGAAGGAAGTGAAACCAGCACCAATAGTTCGTCTGTCACCCTTGAGACACTACAT
CAATTGGCTGCTTCCTATTTTATTGACAGGGACAGCACCCTTCGCAGGCTTCACCATATCCAAA
TTGCATCTACTGCCATCAAGGTGACAGAAACACGGACGGGTCCTCTTGGCTGCAGTAACTATGA
CAACCTAGATTCTGTCAGCTCTGTCTTGGTTCAGAGTCCAGAGAATAAAATTCAGTTGCAAGGG
CTTCAAGTTCTCCTTCCCGACTACCTTCAGGAACGTTTTGTACAGGCAGCGTTGAGCTACATTG
CTTGTAATTCTGAGGGGGAGTTTATCTGCAAGGAGAATGACTGCTGGTGCCTCTGTGGTCCAAA
ATTCCCAGAATGCAATTGCCCCTCCATGGATATTCAAGCCATGGAAGAGAATCTTCTTCGAATA
ACTGAAACATGGAAAGCCTACAACAGTGACTTTGAAGATTCAGATGAATTCAAGTTCTTTATGA
AAAGACTACCCATGAATTATTTCCTCAACACTTCAACTATAATGCATTTGTGGACAATGGATTC
TAATTTTCAGCGCCGCTATGAACAACTAGAGAACAGCATGAAGCAGCTTTTCCTGAAGGCACAT
AGAATTGTACACAAGCTCTTTAGCCTTAGCAAACGGTGCCACAAGCAGCCTCTCATCAGCCTGC
CAAGACAGAGAACTTCAACCTACTGGCTCACTCGCATCCAGTCTTTTCTCTACTGCAATGAAAA
TGGCCTTCTGGGTAGCTTCTCCGAGGAAACCCATTCCTGCACATGCCCCAACGACCAGGTAGTG
TGCACAGCCTTTCTGCCCTGTACCGTGGGCGATGCCTCGGCCTGCCTGACCTGTGCACCTGACA
ATCGCACCCGCTGTGGCACCTGCAACACGGGTTACATGCTGAGCCAGGGACTCTGCAAGCCTGA
AGTCGCTGAGTCAACAGATCATTACATTGGCTTTGAGACCGACCTGCAAGACCTGGAGATGAAA
TACCTGTTGCAGAAAACAGACAGACGAATAGAAGTCCACGCCATCTTTATCAGTAATGACATGC
GCCTCAACAGCTGGTTTGATCCTTCCTGGAGAAAGAGGATGCTCCTGACCTTGAAGAGTAACAA
GTACAAGTCCAGTCTGGTCCACATGATCTTAGGTCTGTCTTTACAGATTTGCTTAACTAAAAAC
AGCACGTTGGAGCCAGTGCTGGCTGTTTACATCAATCCCTTTGGAGGCAGCCACTCCGAGAGCT
GGTTTATGCCTGTGAGCGAGAGCAGCTTTCCAGACTGGGAGCGGACTAAATTGGACCTTCCACT
GCAGTGCTATAACTGGACACTGACTCTGGGAAACAAATGGAAGACATTCTTTGAGACAGTACAC
ATCTACCTGAGGAGTCGCATCAAAGCAAATGGCCCCAACAGCAATGAGAGCATTTACTACGAGC
CTTTGGAGTTTATTGACCCATCCCGGAACCTGGGCTACATGAAAATCAACAACATCCAAGTGTT
TGGCTACAGCATGCACTTTGACCCAGAAGCCATTCGGGACCTGATTTTGCAGCTGGACTACCCC
TACACTCAGGGATCCCAGGACTCGGCACTTTTGCAACTACTAGAGATAAGAGACCGTGTAAATA
AACTCTCCCCACCTGGTCAGCGACGCCTGGATCTGTTTTCTTGCTTGCTTCGTCATAGACTCAA
GTTGTCTACTAGTGAGGTGGTGAGAATTCAATCTGCTCTTCAGGCATTTAATGCCAAGTTGCCA
AACACAGTGGATTATGACACAACCAAATTATGTAGTTAACCTTAAATGTCAAGCACAACCCAAA
ATCTTGGAGGAGTTTTTACAGTGCTTTTGTGGAAGTTTATGTTTGGAAAAGTAAATTTAAATTG
TCTTTTCAATATCTGTCTTATATCAGTCAATAACGTTGGATGGCAATTTACACACATGAACTTG
CTGACAATGAATATATTATACTACAGTTTTGGTTTATGAATGAAATAAATACTGACACCAGTCT
AGAAGACATTCTACTTTTTACAATAAATTTCATTTGTAATTTTATATGTTCCGTGGCAATGCTT
TTGTGCATTACATCCTCTAGAGGGAACATAAAAAGATATAAATAAAATTTTGTAGCTGAACAGT
TATTAACAAGAA

hide sequence

RefSeq Acc Id:

XM_017598682 ⟹ XP_017454171

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	60,966,460 - 61,397,044 (+)	NCBI
mRatBN7.2	13	58,416,181 - 58,846,828 (+)	NCBI
Rnor_6.0	13	63,529,799 - 63,959,390 (+)	NCBI

Sequence:

show sequence

TCTACTTGTACGGGTAAAATGCACTTTCTCTTCTGTGTGAGCTGTCAAACAGCTGTTGGAAAAG
AGGAGGAGGTGACCCGGGTTACAGATTAACCCTAGCATTCCTTGCAGAGGATAGCCAGACAAAT
GTGTGTAAGCAAGGAAGAAAACCCCAAGCTGTAAAGCTGTCACAGCAGTGTGGAGACAGATGAT
TCAGAATTTGGGGACTTTTTCTTTGATTTGCTTGTCGTCATGCAGTTAACCAGGTGTTGAAGGA
AAGCTGAGAGGATGAAGGCTCTAAGTCCCCAGTGGAAGCATGATATGGCGGCGCAGAGCTGGTG
CTGAATTGTCCTCTCTGATGGCTCTATGGGAGTGGATAGTACTGAGTCTTCATTGCTGGGTTTT
AGCGGTTGCTGCTGTCTCTGACCAGCATGCCACAAGCCCCTTCGACTGGCTCCTCTCTGATAAG
GGACCCTTCCATCGCTCACAGGAGTACACAGATTTTGTGGACAGAAGCCGACAGGGATTTAGCA
CAAGATACAAGATATACAGGGAGTTTGGCCGTTGGAAGGTAAATAACCTTGCAGTTGAGAGAAG
AAATTTCCTTGGCTCTCCTCTGCCTCTTGCCCCTGAATTCTTCCGCAATATAAGGCTTTTGGGA
CGACGACCTACACTTCAGCAAATCACAGAAAATCTTATCAAGAAATATGGGACTCATTTCTTGC
TATCAGCTACTCTGGGAGGAGAGGAGTCACTCACAATTTTTGTGGACAAGCGGAAGCTGAGCAA
ACGACCAGAAGGAAGTGAAACCAGCACCAATAGTTCGTCTGTCACCCTTGAGACACTACATCAA
TTGGCTGCTTCCTATTTTATTGACAGGGACAGCACCCTTCGCAGGCTTCACCATATCCAAATTG
CATCTACTGCCATCAAGGTGACAGAAACACGGACGGGTCCTCTTGGCTGCAGTAACTATGACAA
CCTAGATTCTGTCAGCTCTGTCTTGGTTCAGAGTCCAGAGAATAAAATTCAGTTGCAAGGGCTT
CAAGTTCTCCTTCCCGACTACCTTCAGGAACGTTTTGTACAGGCAGCGTTGAGCTACATTGCTT
GTAATTCTGAGGGGGAGTTTATCTGCAAGGAGAATGACTGCTGGTGCCTCTGTGGTCCAAAATT
CCCAGAATGCAATTGCCCCTCCATGGATATTCAAGCCATGGAAGAGAATCTTCTTCGAATAACT
GAAACATGGAAAGCCTACAACAGTGACTTTGAAGATTCAGATGAATTCAAGTTCTTTATGAAAA
GACTACCCATGAATTATTTCCTCAACACTTCAACTATAATGCATTTGTGGACAATGGATTCTAA
TTTTCAGCGCCGCTATGAACAACTAGAGAACAGCATGAAGCAGCTTTTCCTGAAGGCACATAGA
ATTGTACACAAGCTCTTTAGCCTTAGCAAACGGTGCCACAAGCAGCCTCTCATCAGCCTGCCAA
GACAGAGAACTTCAACCTACTGGCTCACTCGCATCCAGTCTTTTCTCTACTGCAATGAAAATGG
CCTTCTGGGTAGCTTCTCCGAGGAAACCCATTCCTGCACATGCCCCAACGACCAGGTAGTGTGC
ACAGCCTTTCTGCCCTGTACCGTGGGCGATGCCTCGGCCTGCCTGACCTGTGCACCTGACAATC
GCACCCGCTGTGGCACCTGCAACACGGGTTACATGCTGAGCCAGGGACTCTGCAAGCCTGAAGT
CGCTGAGTCAACAGATCATTACATTGGCTTTGAGACCGACCTGCAAGACCTGGAGATGAAATAC
CTGTTGCAGAAAACAGACAGACGAATAGAAGTCCACGCCATCTTTATCAGTAATGACATGCGCC
TCAACAGCTGGTTTGATCCTTCCTGGAGAAAGAGGATGCTCCTGACCTTGAAGAGTAACAAGTA
CAAGTCCAGTCTGGTCCACATGATCTTAGGTCTGTCTTTACAGATTTGCTTAACTAAAAACAGC
ACGTTGGAGCCAGTGCTGGCTGTTTACATCAATCCCTTTGGAGGCAGCCACTCCGAGAGCTGGT
TTATGCCTGTGAGCGAGAGCAGCTTTCCAGACTGGGAGCGGACTAAATTGGACCTTCCACTGCA
GTGCTATAACTGGACACTGACTCTGGGAAACAAATGGAAGACATTCTTTGAGACAGTACACATC
TACCTGAGGAGTCGCATCAAAGCAAATGGCCCCAACAGCAATGAGAGCATTTACTACGAGCCTT
TGGAGTTTATTGACCCATCCCGGAACCTGGGCTACATGAAAATCAACAACATCCAAGTGTTTGG
CTACAGCATGCACTTTGACCCAGAAGCCATTCGGGACCTGATTTTGCAGCTGGACTACCCCTAC
ACTCAGGGATCCCAGGACTCGGCACTTTTGCAACTACTAGAGATAAGAGACCGTGTAAATAAAC
TCTCCCCACCTGGTCAGCGACGCCTGGATCTGTTTTCTTGCTTGCTTCGTCATAGACTCAAGTT
GTCTACTAGTGAGGTGGTGAGAATTCAATCTGCTCTTCAGGCATTTAATGCCAAGTTGCCAAAC
ACAGTGGATTATGACACAACCAAATTATGTAGTTAACCTTAAATGTCAAGCACAACCCAAAATC
TTGGAGGAGTTTTTACAGTGCTTTTGTGGAAGTTTATGTTTGGAAAAGTAAATTTAAATTGTCT
TTTCAATATCTGTCTTATATCAGTCAATAACGTTGGATGGCAATTTACACACATGAACTTGCTG
ACAATGAATATATTATACTACAGTTTTGGTTTATGAATGAAATAAATACTGACACCAGTCTAGA
AGACATTCTACTTTTTACAATAAATTTCATTTGTAATTTTATATGTTCCGTGGCAATGCTTTTG
TGCATTACATCCTCTAGAGGGAACATAAAAAGATATAAATAAAATTTTGTAGCTGAACAGTTAT
TAACAAGAA

hide sequence

RefSeq Acc Id:

XM_039090416 ⟹ XP_038946344

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	60,975,185 - 61,397,044 (+)	NCBI
mRatBN7.2	13	58,424,788 - 58,846,828 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_775144	(Get FASTA)	NCBI Sequence Viewer
	XP_017454169	(Get FASTA)	NCBI Sequence Viewer
	XP_017454171	(Get FASTA)	NCBI Sequence Viewer
	XP_038946344	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAC03100	(Get FASTA)	NCBI Sequence Viewer
	EDM09595	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003788
	ENSRNOP00000003788.2
	ENSRNOP00055001037
	ENSRNOP00060005862
	ENSRNOP00065005941
GenBank Protein	Q8K1M7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_775144 ⟸ NM_173121
- Peptide Label:	precursor
- UniProtKB:	Q8K1M7 (UniProtKB/Swiss-Prot), A6ICQ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIWRRRAGAELSSLMALWEWIVLSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFV DRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLI KKYGTHFLLSATLGGEESLTIFVDKRKLSKRPEGSETSTNSSSVTLETLHQLAASYFIDRDSTL RRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFV QAALSYIACNSEGEFICKENDCWCLCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEDS DEFKFFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAHRIVHKLFSLSKRCH KQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASA CLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHA IFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYINPF GGSHSESWFMPVSESSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKANGPNS NESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLL EIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTVDYDTTKLCS hide sequence

RefSeq Acc Id:	XP_017454169 ⟸ XM_017598680
- Peptide Label:	isoform X1
- UniProtKB:	Q8K1M7 (UniProtKB/Swiss-Prot), A6ICQ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIWRRRAGAELSSLMALWEWIVLSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFV DRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLI KKYGTHFLLSATLGGEESLTIFVDKRKLSKRPEGSETSTNSSSVTLETLHQLAASYFIDRDSTL RRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFV QAALSYIACNSEGEFICKENDCWCLCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEDS DEFKFFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAHRIVHKLFSLSKRCH KQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASA CLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHA IFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYINPF GGSHSESWFMPVSESSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKANGPNS NESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLL EIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTVDYDTTKLCS hide sequence

RefSeq Acc Id:	XP_017454171 ⟸ XM_017598682
- Peptide Label:	isoform X1
- UniProtKB:	Q8K1M7 (UniProtKB/Swiss-Prot), A6ICQ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIWRRRAGAELSSLMALWEWIVLSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFV DRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLI KKYGTHFLLSATLGGEESLTIFVDKRKLSKRPEGSETSTNSSSVTLETLHQLAASYFIDRDSTL RRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFV QAALSYIACNSEGEFICKENDCWCLCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEDS DEFKFFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAHRIVHKLFSLSKRCH KQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASA CLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHA IFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYINPF GGSHSESWFMPVSESSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKANGPNS NESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLL EIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTVDYDTTKLCS hide sequence

RefSeq Acc Id:

ENSRNOP00000003788 ⟸ ENSRNOT00000003788

RefSeq Acc Id:	XP_038946344 ⟸ XM_039090416
- Peptide Label:	isoform X1
- UniProtKB:	Q8K1M7 (UniProtKB/Swiss-Prot), A6ICQ2 (UniProtKB/TrEMBL)

Protein Domains

MACPF

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8K1M7-F1-model_v2	AlphaFold	Q8K1M7	1-766	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708421	AgrOrtholog
BioCyc Gene	G2FUF-17983	BioCyc
Ensembl Genes	ENSRNOG00000002811	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055000754	UniProtKB/Swiss-Prot
	ENSRNOG00060004664	UniProtKB/Swiss-Prot
	ENSRNOG00065005663	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000003788	ENTREZGENE
	ENSRNOT00000003788.4	UniProtKB/Swiss-Prot
	ENSRNOT00055001292	UniProtKB/Swiss-Prot
	ENSRNOT00060007803	UniProtKB/Swiss-Prot
	ENSRNOT00065008440	UniProtKB/Swiss-Prot
InterPro	BRINP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Growth_fac_rcpt_cys_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MACPF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:286901	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	286901	ENTREZGENE
PANTHER	BMP/RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MACPF DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam	BRINP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MACPF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Brinp3	PhenoGen
RatGTEx	ENSRNOG00000002811	RatGTEx
	ENSRNOG00055000754	RatGTEx
	ENSRNOG00060004664	RatGTEx
	ENSRNOG00065005663	RatGTEx
SMART	MACPF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Growth factor receptor domain	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt	A6ICQ2	ENTREZGENE, UniProtKB/TrEMBL
	BRNP3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-08	Brinp3	BMP/retinoic acid-inducible neural-specific protein 3			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar