Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LRRC15 mRNA | CTD | PMID:36331819 | 17beta-estradiol | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Estradiol results in increased expression of LRRC15 mRNA | CTD | PMID:31614463 | 17beta-estradiol 3-benzoate | increases methylation | EXP | | 6480464 | estradiol 3-benzoate results in increased methylation of LRRC15 promoter | CTD | PMID:27415467 | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:36804509 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRRC15 mRNA | CTD | PMID:22903824 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | 4,4'-sulfonyldiphenol | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | bisphenol S results in increased expression of LRRC15 mRNA | CTD | PMID:30951980 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of LRRC15 mRNA | CTD | PMID:28959563 | Aflatoxin B2 alpha | increases methylation | ISO | LRRC15 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of LRRC15 3' UTR | CTD | PMID:30157460 | all-trans-retinoic acid | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in decreased expression of LRRC15 mRNA and [bisphenol F co-treated with Tretinoin] results in decreased expression of LRRC15 mRNA | CTD | PMID:30951980 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of LRRC15 mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of LRRC15 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | affects methylation | ISO | LRRC15 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LRRC15 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | LRRC15 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of LRRC15 5' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LRRC15 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of LRRC15 mRNA | CTD | PMID:35479511 | bisphenol A | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in decreased expression of LRRC15 mRNA | CTD | PMID:30951980 | bisphenol A | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LRRC15 mRNA | CTD | PMID:25594700 and PMID:30951980 | bisphenol F | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of LRRC15 mRNA | CTD | PMID:30951980 | bisphenol F | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | bisphenol F results in increased expression of LRRC15 mRNA | CTD | PMID:30951980 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of LRRC15 mRNA | CTD | PMID:19167457 | calcitriol | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of LRRC15 mRNA | CTD | PMID:26485663 | cantharidin | decreases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of LRRC15 mRNA | CTD | PMID:36907384 | capecitabine | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Capecitabine results in decreased expression of LRRC15 mRNA | CTD | PMID:36183961 | CGP 52608 | multiple interactions | ISO | LRRC15 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LRRC15 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of LRRC15 mRNA | CTD | PMID:37019170 | choline | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LRRC15 gene | CTD | PMID:20938992 | Didecyldimethylammonium | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | didecyldimethylammonium results in decreased expression of LRRC15 mRNA | CTD | PMID:32763356 | doxorubicin | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of LRRC15 mRNA | CTD | PMID:29803840 | ethylparaben | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of LRRC15 mRNA | CTD | PMID:37690743 | flavonoids | decreases expression | EXP | | 6480464 | Flavonoids results in decreased expression of LRRC15 mRNA | CTD | PMID:18035473 | folic acid | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LRRC15 gene | CTD | PMID:20938992 | genistein | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Genistein results in increased expression of LRRC15 mRNA | CTD | PMID:20884965 | genistein | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | Genistein results in increased expression of LRRC15 mRNA | CTD | PMID:32186404 | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of LRRC15 mRNA | CTD | PMID:29933104 | L-methionine | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LRRC15 gene | CTD | PMID:20938992 | Licochalcone B | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | licochalcone B results in increased expression of LRRC15 mRNA | CTD | PMID:33647349 | lipopolysaccharide | multiple interactions | ISO | LRRC15 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of LRRC15 mRNA] | CTD | PMID:35811015 | lipopolysaccharide | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of LRRC15 mRNA | CTD | PMID:35811015 | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of LRRC15 mRNA | CTD | PMID:28801915 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of LRRC15 mRNA | CTD | PMID:28801915 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LRRC15 mRNA | CTD | PMID:20360939 | ozone | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of LRRC15 mRNA | CTD | PMID:27106289 | paracetamol | decreases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LRRC15 mRNA | CTD | PMID:26690555 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LRRC15 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Lrrc15 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LRRC15 mRNA | CTD | PMID:36331819 | phenethyl caffeate | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LRRC15 mRNA | CTD | PMID:20360939 | potassium dichromate | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of LRRC15 mRNA | CTD | PMID:23608068 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | LRRC15 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of LRRC15 mRNA] | CTD | PMID:35811015 | sodium arsenite | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of LRRC15 mRNA | CTD | PMID:22714537 | sodium arsenite | decreases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of LRRC15 mRNA | CTD | PMID:36209798 | tetrachloroethene | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | Tetrachloroethylene results in increased expression of LRRC15 mRNA | CTD | PMID:28973375 | titanium dioxide | decreases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of LRRC15 mRNA | CTD | PMID:29264374 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of LRRC15 mRNA | CTD | PMID:33387578 | triptonide | increases expression | ISO | Lrrc15 (Mus musculus) | 6480464 | triptonide results in increased expression of LRRC15 mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Urethane results in increased expression of LRRC15 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LRRC15 mRNA | CTD | PMID:23179753 and PMID:28001369 | valproic acid | affects expression | ISO | LRRC15 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of LRRC15 mRNA | CTD | PMID:25979313 | |