Gene: Slit1 (slit guidance ligand 1) Rattus norvegicus
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Symbol: Slit1
Name: slit guidance ligand 1
Description: ENCODES a protein that exhibits heparan sulfate proteoglycan binding; Roundabout binding (ortholog); INVOLVED IN brain development; negative regulation of axon extension involved in axon guidance; spinal cord development; ASSOCIATED WITH Brain Injuries; Spinal Cord Injuries (ortholog); FOUND IN extracellular space; INTERACTS WITH 17alpha-ethynylestradiol; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MEGF4; multiple EGF-like domains protein 4; multiple epidermal growth factor-like domains 4; multiple epidermal growth factor-like domains protein 4; slit (Drosophila) homolog 1; slit homolog 1 (Drosophila); slit homolog 1 protein; slit-1
Orthologs:
Homo sapiens (human) : SLIT1 (slit guidance ligand 1)  HGNC  AGR
Mus musculus (house mouse) : Slit1 (slit guidance ligand 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Slit1 (slit guidance ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLIT1 (slit guidance ligand 1)
Canis lupus familiaris (dog) : SLIT1 (slit guidance ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slit1 (slit guidance ligand 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01260,843,481 - 260,992,366 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01268,298,678 - 268,445,090 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41246,813,909 - 246,964,408 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11246,928,385 - 247,078,883 (-)NCBI
Celera1236,249,200 - 236,395,640 (-)NCBI
Cytogenetic Map1q54NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slit1
AGR Gene
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 69307
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE