Gene: Cyp27b1 (cytochrome P450, family 27, subfamily b, polypeptide 1) Rattus norvegicus
Symbol: Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Description: ENCODES a protein that exhibits calcidiol 1-monooxygenase activity; INVOLVED IN aging; lactation; response to calcium ion; PARTICIPATES IN Mycobacterium tuberculosis infection pathway; steroid biosynthetic pathway; ASSOCIATED WITH Acidosis; Acute Kidney Injury; Diabetes Mellitus, Experimental; FOUND IN mitochondrion; cytoplasm (ortholog); INTERACTS WITH 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; bisphenol A; calcidiol
Type: protein-coding
Also known as: 25-hydroxyvitamin D(3) 1-alpha-hydroxylase; 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; 25-OHD-1 alpha-hydroxylase; calcidiol 1-monooxygenase; Cyp40; cytochrome p450 27B1; cytochrome P450 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase); cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1; cytochrome P450 subfamily XXVIIB polypeptide 1; cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase); cytochrome P450, subfamily 27b, polypeptide 1; cytochrome P450, subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase), polypeptide 1; cytochrome P450C1 alpha; cytochrome P450VD1-alpha; P450C1 alpha; P450VD1-alpha; VD3 1A hydroxylase
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0770,333,150 - 70,340,006 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0770,512,763 - 70,517,707 (+)NCBIRnor5.0rn5Rnor5.0
Celera760,014,507 - 60,019,451 (+)NCBI
Cytogenetic Map7 NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyp27b1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 69192
Created: 2001-11-13
Species: Rattus norvegicus
Last Modified: 2016-09-06
Status: ACTIVE