Gene: Wfs1 (wolframin ER transmembrane glycoprotein) Rattus norvegicus
Symbol: Wfs1
Name: wolframin ER transmembrane glycoprotein
Description: ENCODES a protein that exhibits activating transcription factor binding; calcium-dependent protein binding; calmodulin binding; INVOLVED IN negative regulation of ATF6-mediated unfolded protein response; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Seizures; Stress Disorders, Post-Traumatic; Cataract, Nuclear Total (ortholog); FOUND IN proteasome complex; endoplasmic reticulum (ortholog); integral component of endoplasmic reticulum membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; Decabromodiphenyl oxide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Wolfram syndrome 1; Wolfram syndrome 1 (wolframin); Wolfram syndrome 1 homolog; Wolfram syndrome 1 homolog (human); wolframin
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01478,640,707 - 78,665,224 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01478,606,172 - 78,630,689 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41479,379,680 - 79,404,003 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11479,389,637 - 79,406,394 (+)NCBI
Celera1472,756,725 - 72,781,236 (+)NCBI
Cytogenetic Map14q21NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Wfs1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 68954
Created: 2001-11-06
Species: Rattus norvegicus
Last Modified: 2016-06-07
Status: ACTIVE