Zfp182 (zinc finger protein 182) - Rat Genome Database

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Gene: Zfp182 (zinc finger protein 182) Rattus norvegicus
Analyze
Symbol: Zfp182
Name: zinc finger protein 182
RGD ID: 6490591
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF182 (zinc finger protein 182); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; methoxychlor.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911831; zinc finger protein 182-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X3,480,991 - 3,555,009 (+)NCBIGRCr8
mRatBN7.2X927,439 - 1,001,474 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX899,439 - 1,000,954 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX955,573 - 1,029,581 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X4,431,265 - 4,505,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X751,810 - 825,834 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X908,536 - 1,000,718 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX984,798 - 999,834 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X916,198 - 995,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX1,484,228 - 1,570,793 (+)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Zfp182
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X3,480,991 - 3,555,009 (+)NCBIGRCr8
mRatBN7.2X927,439 - 1,001,474 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX899,439 - 1,000,954 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX955,573 - 1,029,581 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X4,431,265 - 4,505,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X751,810 - 825,834 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X908,536 - 1,000,718 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX984,798 - 999,834 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X916,198 - 995,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX1,484,228 - 1,570,793 (+)NCBICelera
Cytogenetic MapXq11NCBI
ZNF182
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X47,974,851 - 48,003,989 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX47,974,851 - 48,003,989 (-)EnsemblGRCh38hg38GRCh38
GRCh37X47,834,250 - 47,863,388 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X47,719,194 - 47,748,321 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX52,029,773 - 52,058,920 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX45,547,356 - 45,575,714 (-)NCBIHuRef
CHM1_1X47,865,391 - 47,894,538 (-)NCBICHM1_1
T2T-CHM13v2.0X47,385,028 - 47,414,166 (-)NCBIT2T-CHM13v2.0
Zfp182
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X20,892,423 - 20,928,357 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX20,895,178 - 20,928,555 (-)EnsemblGRCm39 Ensembl
GRCm38X21,026,184 - 21,062,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX21,028,939 - 21,062,316 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X20,603,310 - 20,639,164 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X20,185,898 - 20,218,962 (-)NCBIMGSCv36mm8
CeleraX19,160,338 - 19,196,114 (-)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX16.55NCBI
Znf182
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495551693,596 - 148,739 (+)NCBIChiLan1.0ChiLan1.0
ZNF182
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X49,594,944 - 49,628,099 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X49,598,316 - 49,631,479 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,404,284 - 40,435,360 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,297,256 - 48,327,881 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX48,298,563 - 48,394,699 (-)Ensemblpanpan1.1panPan2
ZNF182
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,557,362 - 41,584,417 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,558,053 - 41,652,020 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,935,152 - 15,962,225 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X41,694,792 - 41,736,751 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX41,694,858 - 41,721,825 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X41,682,063 - 41,723,993 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X41,670,133 - 41,712,078 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X41,763,646 - 41,805,642 (-)NCBIUU_Cfam_GSD_1.0
LOC101954588
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,092,406 - 34,101,983 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721289,508 - 323,119 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721288,584 - 342,402 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF182
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,444,230 - 42,473,285 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,444,227 - 42,473,308 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,051,652 - 47,080,724 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF182
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,138,483 - 45,185,295 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,139,806 - 45,152,280 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607610,403,825 - 10,435,567 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Zfp182
181 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:70
Interacting mature miRNAs:72
Transcripts:ENSRNOT00000073016
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat

Markers in Region
px-23b1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X999,549 - 999,659 (+)MAPPERmRatBN7.2
mRatBN7.2X999,549 - 1,000,247 (+)MAPPERmRatBN7.2
Rnor_6.0X998,808 - 998,917NCBIRnor6.0
Rnor_6.0X998,808 - 999,505NCBIRnor6.0
Rnor_5.0X993,656 - 994,353UniSTSRnor5.0
Rnor_5.0X993,656 - 993,765UniSTSRnor5.0
CeleraX1,568,883 - 1,569,580UniSTS
CeleraX1,568,883 - 1,568,992UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 10 21 6 18 6 74 22 34 11
Low 2 33 36 35 1 35 8 10 13 7 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000073016   ⟹   ENSRNOP00000067088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX928,786 - 1,000,954 (+)Ensembl
Rnor_6.0 EnsemblX984,798 - 999,834 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108239   ⟹   ENSRNOP00000085393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX899,439 - 1,000,954 (+)Ensembl
RefSeq Acc Id: NM_001401240   ⟹   NP_001388169
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,480,991 - 3,555,009 (+)NCBI
mRatBN7.2X927,439 - 1,001,460 (+)NCBI
RefSeq Acc Id: NM_001401241   ⟹   NP_001388170
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,480,991 - 3,555,009 (+)NCBI
mRatBN7.2X927,439 - 1,001,460 (+)NCBI
RefSeq Acc Id: XM_039100573   ⟹   XP_038956501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,346 - 3,555,009 (+)NCBI
mRatBN7.2X928,915 - 1,001,474 (+)NCBI
RefSeq Acc Id: XM_039100575   ⟹   XP_038956503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,291 - 3,555,009 (+)NCBI
mRatBN7.2X927,442 - 1,001,474 (+)NCBI
RefSeq Acc Id: XM_039100584   ⟹   XP_038956512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,291 - 3,555,009 (+)NCBI
mRatBN7.2X927,442 - 1,001,474 (+)NCBI
RefSeq Acc Id: XM_039100585   ⟹   XP_038956513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,210 - 3,555,009 (+)NCBI
mRatBN7.2X927,442 - 1,001,474 (+)NCBI
RefSeq Acc Id: XM_039100588   ⟹   XP_038956516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,328 - 3,555,009 (+)NCBI
mRatBN7.2X927,442 - 1,001,474 (+)NCBI
RefSeq Acc Id: XM_063279709   ⟹   XP_063135779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,346 - 3,555,009 (+)NCBI
RefSeq Acc Id: XM_063279710   ⟹   XP_063135780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,311 - 3,555,009 (+)NCBI
RefSeq Acc Id: XM_063279711   ⟹   XP_063135781
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,482,301 - 3,555,009 (+)NCBI
RefSeq Acc Id: XM_063279712   ⟹   XP_063135782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X3,539,443 - 3,555,009 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000067088   ⟸   ENSRNOT00000073016
RefSeq Acc Id: XP_038956503   ⟸   XM_039100575
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A273 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956512   ⟸   XM_039100584
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A273 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956516   ⟸   XM_039100588
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A273 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956513   ⟸   XM_039100585
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A273 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956501   ⟸   XM_039100573
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A273 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000085393   ⟸   ENSRNOT00000108239
RefSeq Acc Id: NP_001388170   ⟸   NM_001401241
- Peptide Label: precursor
RefSeq Acc Id: NP_001388169   ⟸   NM_001401240
- Peptide Label: precursor
RefSeq Acc Id: XP_063135781   ⟸   XM_063279711
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A273 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135780   ⟸   XM_063279710
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A273 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135779   ⟸   XM_063279709
- Peptide Label: isoform X2
- UniProtKB: M0RBY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135782   ⟸   XM_063279712
- Peptide Label: isoform X3
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RBY6-F1-model_v2 AlphaFold M0RBY6 1-604 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6490591 AgrOrtholog
BioCyc Gene G2FUF-3206 BioCyc
Ensembl Genes ENSRNOG00000047132 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073016.3 UniProtKB/TrEMBL
  ENSRNOT00000108239.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
NCBI Gene LOC100911831 ENTREZGENE
PANTHER KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 382 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 939 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp182 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047132 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I6A273 ENTREZGENE, UniProtKB/TrEMBL
  M0RBY6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-09 Zfp182  zinc finger protein 182  LOC100911831  zinc finger protein 182-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911831  zinc finger protein 182-like      Symbol and Name status set to provisional 70820 PROVISIONAL