Sp7 (Sp7 transcription factor) - Rat Genome Database

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Gene: Sp7 (Sp7 transcription factor) Rattus norvegicus
Analyze
Symbol: Sp7
Name: Sp7 transcription factor
RGD ID: 631377
Description: Predicted to enable DEAD/H-box RNA helicase binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to zinc ion starvation; response to insulin; and response to organic cyclic compound. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 12. Orthologous to human SP7 (Sp7 transcription factor); INTERACTS WITH 5-formyltetrahydrofolic acid; ammonium chloride; arsenous acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: osterix; Osx; Transcription factor Sp7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,363,193 - 135,373,376 (-)NCBIGRCr8
mRatBN7.27133,484,609 - 133,494,788 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,484,609 - 133,494,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,247,146 - 135,255,771 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,476,525 - 137,485,150 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,461,680 - 137,470,323 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,957,316 - 143,967,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,958,858 - 143,967,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,753,826 - 141,762,790 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,109,771 - 141,118,397 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,186,207 - 141,194,213 (-)NCBI
Celera7129,919,226 - 129,927,844 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-di-tert-butylphenol  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methyladenine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-azacytidine  (ISO)
5-formyltetrahydrofolic acid  (EXP)
Actein  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
aluminium oxide  (ISO)
ammonium chloride  (EXP)
arsenous acid  (EXP)
aucubin  (ISO)
benzo[a]pyrene  (ISO)
berberine  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calciol  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
cannabidiol  (ISO)
CHIR 99021  (ISO)
chromium(3+) trichloride  (ISO)
cobalt dichloride  (EXP,ISO)
cordycepin  (ISO)
D-glucose  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
disodium selenite  (ISO)
ethyl 3,4-dihydroxybenzoate  (ISO)
fentin hydroxide  (ISO)
folic acid  (ISO)
fructose  (ISO)
fulvestrant  (EXP,ISO)
gamma-aminobutyric acid  (EXP)
gamma-Oryzanol (TN)  (EXP)
genistein  (ISO)
Ginkgoic acid  (ISO)
glucose  (ISO)
glycerol 1-phosphate  (ISO)
glycerol 2-phosphate  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
herbicide  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
ionomycin  (ISO)
isonicotinamide  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
menaquinone  (EXP)
metformin  (ISO)
methotrexate  (EXP)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Morroniside  (ISO)
naringin  (EXP,ISO)
notoginsenoside R1  (ISO)
Octicizer  (ISO)
ozone  (ISO)
pioglitazone  (ISO)
prallethrin  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quinoxyfen  (ISO)
resveratrol  (ISO)
Salidroside  (ISO)
SB 203580  (EXP)
simvastatin  (ISO)
sodium fluoride  (EXP,ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (EXP)
Theaflavin 3,3'-digallate  (ISO)
titanium dioxide  (ISO)
tributyl phosphate  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
warfarin  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Increased expression of the receptor for activation of NF-kappaB and decreased runt-related transcription factor 2 expression in bone of rats with streptozotocin-induced diabetes. Hie M and Tsukamoto I, Int J Mol Med. 2010 Oct;26(4):611-8. doi: 10.3892/ijmm_00000506.
3. Zinc deficiency decreases osteoblasts and osteoclasts associated with the reduced expression of Runx2 and RANK. Hie M, etal., Bone. 2011 Dec;49(6):1152-9. doi: 10.1016/j.bone.2011.08.019. Epub 2011 Aug 26.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Nakashima K, etal., Cell 2002 Jan 11;108(1):17-29.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. [Histopathologic features of degenerative aortic valve and its mechanisms]. Sun J, etal., Zhonghua Yi Xue Za Zhi. 2013 Jan 22;93(4):280-4.
Additional References at PubMed
PMID:14604442   PMID:16041384   PMID:16610234   PMID:17303075   PMID:18270471   PMID:18272339   PMID:18471237   PMID:18932205   PMID:19124839   PMID:19822991   PMID:21806466   PMID:22009963  
PMID:22886301   PMID:23354182   PMID:25823394   PMID:26253417   PMID:26617945   PMID:28107808   PMID:30026585   PMID:30912295   PMID:32910396   PMID:33187585   PMID:34245724  


Genomics

Comparative Map Data
Sp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,363,193 - 135,373,376 (-)NCBIGRCr8
mRatBN7.27133,484,609 - 133,494,788 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,484,609 - 133,494,847 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,247,146 - 135,255,771 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,476,525 - 137,485,150 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,461,680 - 137,470,323 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,957,316 - 143,967,488 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,958,858 - 143,967,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,753,826 - 141,762,790 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,109,771 - 141,118,397 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,186,207 - 141,194,213 (-)NCBI
Celera7129,919,226 - 129,927,844 (-)NCBICelera
Cytogenetic Map7q36NCBI
SP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,326,575 - 53,344,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,326,575 - 53,345,315 (-)EnsemblGRCh38hg38GRCh38
GRCh371253,720,359 - 53,738,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,006,626 - 52,015,804 (-)NCBINCBI36Build 36hg18NCBI36
Build 341252,006,628 - 52,015,804NCBI
Celera1253,369,632 - 53,379,307 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,761,885 - 50,771,562 (-)NCBIHuRef
CHM1_11253,687,545 - 53,697,201 (-)NCBICHM1_1
T2T-CHM13v2.01253,292,290 - 53,310,533 (-)NCBIT2T-CHM13v2.0
Sp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,265,038 - 102,275,498 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,265,041 - 102,275,617 (-)EnsemblGRCm39 Ensembl
GRCm3815102,356,603 - 102,367,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,356,606 - 102,367,182 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715102,187,608 - 102,196,702 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,184,644 - 102,194,367 (-)NCBIMGSCv36mm8
Celera15104,514,244 - 104,523,282 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.51NCBI
Sp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458583,981 - 602,856 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955458583,981 - 602,856 (-)NCBIChiLan1.0ChiLan1.0
SP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,849,740 - 40,859,601 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,846,505 - 40,856,578 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,409,055 - 35,427,871 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,191,091 - 36,209,494 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,199,673 - 36,209,494 (+)Ensemblpanpan1.1panPan2
SP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,878,612 - 1,887,063 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,880,424 - 1,887,679 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,365,530 - 44,382,281 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,871,509 - 1,888,303 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,889,794 - 1,906,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,874,976 - 1,891,740 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,766,164 - 44,782,966 (-)NCBIUU_Cfam_GSD_1.0
Sp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,544,586 - 62,554,293 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,612,060 - 10,619,628 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,610,542 - 10,613,335 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,543,534 - 18,565,776 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,541,368 - 18,566,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,978,684 - 19,002,387 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,436,976 - 49,456,741 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037196,611,275 - 196,624,212 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,436,115 - 1,456,609 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,436,390 - 1,444,996 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sp7
24 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:77
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000018828
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
D7Mit1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,492,707 - 133,492,884 (+)MAPPERmRatBN7.2
Rnor_6.07143,965,415 - 143,965,591NCBIRnor6.0
Rnor_5.07141,760,721 - 141,760,897UniSTSRnor5.0
RGSC_v3.47141,116,327 - 141,116,504RGDRGSC3.4
RGSC_v3.47141,116,328 - 141,116,504UniSTSRGSC3.4
RGSC_v3.17141,192,765 - 141,192,941RGD
Celera7129,925,775 - 129,925,951UniSTS
RH 3.4 Map71065.7UniSTS
RH 3.4 Map71065.7RGD
RH 2.0 Map7799.2RGD
Cytogenetic Map7q36UniSTS
PMC151001P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,486,386 - 133,486,584 (+)MAPPERmRatBN7.2
Rnor_6.07143,959,094 - 143,959,291NCBIRnor6.0
Rnor_5.07141,754,402 - 141,754,599UniSTSRnor5.0
RGSC_v3.47141,110,007 - 141,110,204UniSTSRGSC3.4
Celera7129,919,462 - 129,919,659UniSTS
Cytogenetic Map7q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 46 10 12
Below cutoff 1 6 10 9 3 9 1 2 28 12 19 2 1

Sequence


RefSeq Acc Id: ENSRNOT00000018828   ⟹   ENSRNOP00000018828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,484,953 - 133,494,156 (-)Ensembl
Rnor_6.0 Ensembl7143,958,858 - 143,966,863 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081758   ⟹   ENSRNOP00000074457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7133,484,609 - 133,494,847 (-)Ensembl
Rnor_6.0 Ensembl7143,958,858 - 143,967,484 (-)Ensembl
RefSeq Acc Id: NM_001037632   ⟹   NP_001032721
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,364,735 - 135,373,361 (-)NCBI
mRatBN7.27133,486,151 - 133,494,777 (-)NCBI
Rnor_6.07143,958,858 - 143,967,484 (-)NCBI
Rnor_5.07141,753,826 - 141,762,790 (-)NCBI
RGSC_v3.47141,109,771 - 141,118,397 (-)RGD
Celera7129,919,226 - 129,927,844 (-)RGD
Sequence:
RefSeq Acc Id: NM_181374   ⟹   NP_852039
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,364,735 - 135,372,740 (-)NCBI
mRatBN7.27133,486,151 - 133,494,156 (-)NCBI
Rnor_6.07143,958,858 - 143,966,863 (-)NCBI
Rnor_5.07141,753,826 - 141,762,790 (-)NCBI
RGSC_v3.47141,109,771 - 141,118,397 (-)RGD
Celera7129,919,226 - 129,927,223 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594791   ⟹   XP_017450280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87135,363,193 - 135,373,376 (-)NCBI
mRatBN7.27133,484,609 - 133,494,788 (-)NCBI
Rnor_6.07143,957,316 - 143,967,488 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001032721   ⟸   NM_001037632
- Peptide Label: isoform 1
- UniProtKB: Q6IMK1 (UniProtKB/TrEMBL),   Q811U1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_852039   ⟸   NM_181374
- Peptide Label: isoform 2
- UniProtKB: Q6IMK2 (UniProtKB/TrEMBL),   F7EYG4 (UniProtKB/TrEMBL),   Q811U1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450280   ⟸   XM_017594791
- Peptide Label: isoform X1
- UniProtKB: Q6IMK2 (UniProtKB/TrEMBL),   F7EYG4 (UniProtKB/TrEMBL),   Q811U1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018828   ⟸   ENSRNOT00000018828
RefSeq Acc Id: ENSRNOP00000074457   ⟸   ENSRNOT00000081758
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IMK2-F1-model_v2 AlphaFold Q6IMK2 1-428 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695698
Promoter ID:EPDNEW_R6223
Type:multiple initiation site
Name:Sp7_1
Description:Sp7 transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07143,967,469 - 143,967,529EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631377 AgrOrtholog
BioCyc Gene G2FUF-31938 BioCyc
Ensembl Genes ENSRNOG00000014082 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018828 ENTREZGENE
  ENSRNOT00000018828.4 UniProtKB/TrEMBL
  ENSRNOT00000081758 ENTREZGENE
  ENSRNOT00000081758.2 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:300260 UniProtKB/TrEMBL
NCBI Gene 300260 ENTREZGENE
PANTHER KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR SP7 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Sp7 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014082 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt F7EYG4 ENTREZGENE, UniProtKB/TrEMBL
  Q6IMK1 ENTREZGENE, UniProtKB/TrEMBL
  Q6IMK2 ENTREZGENE, UniProtKB/TrEMBL
  Q811U1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-11 Sp7  Sp7 transcription factor      Symbol and Name status set to approved 625702 APPROVED