Gene: Egln1 (egl-9 family hypoxia-inducible factor 1) Rattus norvegicus
Symbol: Egln1
Name: egl-9 family hypoxia-inducible factor 1
Description: ENCODES a protein that exhibits enzyme binding; peptidyl-proline dioxygenase activity; peptidyl-proline 4-dioxygenase activity (ortholog); INVOLVED IN negative regulation of cAMP catabolic process; negative regulation of cyclic-nucleotide phosphodiesterase activity; negative regulation of sequence-specific DNA binding transcription factor activity; PARTICIPATES IN hypoxia inducible factor pathway; vascular endothelial growth factor signaling pathway; renal cell cancer pathway; ASSOCIATED WITH Erythrocytosis, Familial, 3 (ortholog); FOUND IN cytosol; cytoplasm (ortholog); INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; astemizole
Type: protein-coding
RefSeq Status: MODEL
Also known as: egl nine homolog 1; EGL nine homolog 1 (C. elegans); HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; hypoxia-inducible factor prolyl hydroxylase 2; PHD-2; PHD2; prolyl hydroxylase domain-containing protein 2
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.01957,660,194 - 57,701,158-NCBI
Rat Cytogenetic Map19q12 NCBI
RGSC Genome Assembly v5.01968,373,433 - 68,412,983-NCBI
RGSC Genome Assembly v3.41955,080,670 - 55,118,226-NCBI
Rat Celera Assembly1952,235,066 - 52,273,829-NCBI
Genome Assembly 3.11955,086,125 - 55,122,813-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Egln1
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RGD Object Information
RGD ID: 631375
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2014-09-10
Status: ACTIVE