Kcnq5 (potassium voltage-gated channel subfamily Q member 5) - Rat Genome Database

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Gene: Kcnq5 (potassium voltage-gated channel subfamily Q member 5) Rattus norvegicus
Analyze
Symbol: Kcnq5
Name: potassium voltage-gated channel subfamily Q member 5
RGD ID: 628848
Description: Enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential and voltage-gated potassium channel activity. Involved in potassium ion transport. Is active in calyx of Held and presynaptic membrane. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 46. Orthologous to human KCNQ5 (potassium voltage-gated channel subfamily Q member 5); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Kcnq5l; LOC689123; potassium channel, voltage-gated KQT-like subfamily Q, member 5; potassium voltage-gated channel subfamily KQT member 5; potassium voltage-gated channel, KQT-like subfamily, member 5; potassium voltage-gated channel, subfamily Q, member 5; potassium voltage-gated channel, subfamily Q, member 5-like; similar to Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel alpha subunit KvLQT5) (KQT-like 5)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8931,326,595 - 31,892,399 (-)NCBIGRCr8
mRatBN7.2923,830,185 - 24,395,984 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx932,326,367 - 32,887,878 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0937,447,044 - 38,008,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0935,762,286 - 36,323,828 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0927,565,869 - 28,141,114 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl927,562,959 - 27,761,733 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0926,413,162 - 26,986,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4920,181,402 - 20,767,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1920,293,226 - 20,293,677 (-)NCBI
Celera921,408,169 - 21,967,095 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. The potassium channel KCNQ5/Kv7.5 is localized in synaptic endings of auditory brainstem nuclei of the rat. Caminos E, etal., J Comp Neurol. 2007 Dec 1;505(4):363-78. doi: 10.1002/cne.21497.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KCNQ5 channels control resting properties and release probability of a synapse. Huang H and Trussell LO, Nat Neurosci. 2011 Jun 12;14(7):840-7. doi: 10.1038/nn.2830.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Molecular correlates of the M-current in cultured rat hippocampal neurons. Shah MM, etal., J Physiol 2002 Oct 1;544(Pt 1):29-37.
9. The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels. Yus-Najera E, etal., J Biol Chem 2002 Aug 9;277(32):28545-53.
Additional References at PubMed
PMID:8889548   PMID:10787416   PMID:11159685   PMID:15632090   PMID:15963599   PMID:17071736   PMID:17322297   PMID:18048450   PMID:18331828   PMID:18786918   PMID:19246091   PMID:20151361  
PMID:20624791   PMID:21750731   PMID:24297175   PMID:24446351   PMID:24558103   PMID:24855057   PMID:25421809   PMID:25616413   PMID:28189443   PMID:28669405   PMID:31570602   PMID:32739272  
PMID:33667331  


Genomics

Comparative Map Data
Kcnq5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8931,326,595 - 31,892,399 (-)NCBIGRCr8
mRatBN7.2923,830,185 - 24,395,984 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx932,326,367 - 32,887,878 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0937,447,044 - 38,008,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0935,762,286 - 36,323,828 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0927,565,869 - 28,141,114 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl927,562,959 - 27,761,733 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0926,413,162 - 26,986,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4920,181,402 - 20,767,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1920,293,226 - 20,293,677 (-)NCBI
Celera921,408,169 - 21,967,095 (-)NCBICelera
Cytogenetic Map9q13NCBI
KCNQ5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38672,622,064 - 73,198,853 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl672,621,792 - 73,198,853 (+)EnsemblGRCh38hg38GRCh38
GRCh37673,331,792 - 73,908,576 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36673,388,556 - 73,962,301 (+)NCBINCBI36Build 36hg18NCBI36
Build 34673,388,555 - 73,962,301NCBI
Celera673,724,971 - 74,301,723 (+)NCBICelera
Cytogenetic Map6q13NCBI
HuRef670,530,024 - 71,107,055 (+)NCBIHuRef
CHM1_1673,498,230 - 74,075,278 (+)NCBICHM1_1
T2T-CHM13v2.0673,798,716 - 74,375,478 (+)NCBIT2T-CHM13v2.0
Kcnq5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39121,468,623 - 22,032,874 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl121,468,627 - 22,032,166 (-)EnsemblGRCm39 Ensembl
GRCm38121,398,399 - 21,962,650 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl121,398,403 - 21,961,942 (-)EnsemblGRCm38mm10GRCm38
MGSCv37121,388,484 - 21,952,023 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36121,387,314 - 21,946,732 (-)NCBIMGSCv36mm8
Celera121,280,293 - 21,849,214 (-)NCBICelera
Cytogenetic Map1A4NCBI
cM Map16.67NCBI
Kcnq5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554887,406,635 - 7,927,532 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554887,406,633 - 7,928,526 (+)NCBIChiLan1.0ChiLan1.0
KCNQ5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2592,601,093 - 93,177,834 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1690,526,540 - 91,103,615 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0670,448,161 - 71,025,173 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1673,741,208 - 74,315,757 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl673,742,191 - 74,312,344 (+)Ensemblpanpan1.1panPan2
KCNQ5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11234,872,514 - 35,364,794 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1234,872,581 - 35,362,349 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1234,737,803 - 35,233,429 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01235,413,242 - 35,916,493 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1235,413,242 - 35,913,762 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11234,948,630 - 35,457,677 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01234,986,659 - 35,479,229 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01235,098,552 - 35,603,898 (+)NCBIUU_Cfam_GSD_1.0
Kcnq5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494670,125,573 - 70,658,239 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366184,283,349 - 4,812,036 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366184,283,240 - 4,815,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNQ5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl152,435,235 - 52,939,823 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1152,435,332 - 52,939,705 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2158,773,511 - 59,277,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNQ5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1171,932,962 - 2,495,926 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl171,930,803 - 2,128,570 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660587,855,745 - 8,424,719 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnq5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248196,889,658 - 7,365,537 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248196,886,328 - 7,365,537 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcnq5
4294 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:162
Count of miRNA genes:70
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000018552, ENSRNOT00000040034
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat

Markers in Region
D9Rat180  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2924,116,078 - 24,116,997 (+)MAPPERmRatBN7.2
mRatBN7.2924,116,762 - 24,116,997 (+)MAPPERmRatBN7.2
Rnor_6.0927,858,560 - 27,859,505NCBIRnor6.0
Rnor_6.0927,859,271 - 27,859,505NCBIRnor6.0
Rnor_5.0926,705,889 - 26,706,123UniSTSRnor5.0
Rnor_5.0926,705,178 - 26,706,123UniSTSRnor5.0
RGSC_v3.4920,474,388 - 20,474,623RGDRGSC3.4
RGSC_v3.4920,474,389 - 20,474,623UniSTSRGSC3.4
RGSC_v3.1920,475,802 - 20,476,037RGD
Celera921,690,031 - 21,690,263UniSTS
SHRSP x BN Map920.1098RGD
SHRSP x BN Map920.1098UniSTS
Cytogenetic Map9q13UniSTS
D9Got31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2924,297,837 - 24,298,072 (+)MAPPERmRatBN7.2
Rnor_6.0928,045,520 - 28,045,754NCBIRnor6.0
Rnor_5.0926,890,948 - 26,891,182UniSTSRnor5.0
Celera921,870,523 - 21,870,757UniSTS
RH 3.4 Map9224.5RGD
RH 3.4 Map9224.5UniSTS
RH 2.0 Map9187.0RGD
Cytogenetic Map9q13UniSTS
RH138014  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2924,075,461 - 24,075,696 (+)MAPPERmRatBN7.2
Rnor_6.0927,817,440 - 27,817,674NCBIRnor6.0
Rnor_5.0926,665,206 - 26,665,440UniSTSRnor5.0
Celera921,649,469 - 21,649,703UniSTS
RH 3.4 Map9229.29UniSTS
Cytogenetic Map9q13UniSTS
RH131959  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2924,387,590 - 24,387,771 (+)MAPPERmRatBN7.2
Rnor_6.0928,133,826 - 28,134,006NCBIRnor6.0
Rnor_5.0926,979,169 - 26,979,349UniSTSRnor5.0
RGSC_v3.4920,760,376 - 20,760,556UniSTSRGSC3.4
Celera921,959,807 - 21,959,987UniSTS
RH 3.4 Map9237.0UniSTS
Cytogenetic Map9q13UniSTS
BE106461  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2923,914,507 - 23,914,657 (+)MAPPERmRatBN7.2
Rnor_6.0927,647,434 - 27,647,583NCBIRnor6.0
Rnor_5.0926,494,727 - 26,494,876UniSTSRnor5.0
RGSC_v3.4920,262,523 - 20,262,672UniSTSRGSC3.4
Celera921,489,344 - 21,489,493UniSTS
RH 3.4 Map9229.5UniSTS
Cytogenetic Map9q13UniSTS
RH141099  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2923,833,570 - 23,833,750 (+)MAPPERmRatBN7.2
Rnor_6.0927,566,353 - 27,566,532NCBIRnor6.0
Rnor_5.0926,413,646 - 26,413,825UniSTSRnor5.0
RGSC_v3.4920,181,586 - 20,181,765UniSTSRGSC3.4
Celera921,408,653 - 21,408,832UniSTS
RH 3.4 Map9229.6UniSTS
Cytogenetic Map9q13UniSTS
AU049631  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2923,970,175 - 23,970,321 (+)MAPPERmRatBN7.2
mRatBN7.2923,970,175 - 23,970,479 (+)MAPPERmRatBN7.2
Rnor_6.0927,703,085 - 27,703,228NCBIRnor6.0
Rnor_6.0927,703,085 - 27,703,411NCBIRnor6.0
Rnor_5.0926,550,378 - 26,550,704UniSTSRnor5.0
Rnor_5.0926,550,378 - 26,550,521UniSTSRnor5.0
RGSC_v3.4920,318,182 - 20,318,327UniSTSRGSC3.4
Celera921,544,941 - 21,545,086UniSTS
Cytogenetic Map9q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 3 3 39 1 3
Low 3 22 21 6 19 6 5 8 35 27 41 10 5
Below cutoff 17 31 30 30 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000018552   ⟹   ENSRNOP00000018552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
Rnor_6.0 Ensembl927,565,869 - 27,761,365 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000040034   ⟹   ENSRNOP00000047562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl927,562,959 - 27,761,733 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097073   ⟹   ENSRNOP00000079928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098049   ⟹   ENSRNOP00000097404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106244   ⟹   ENSRNOP00000084442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl923,833,087 - 24,394,704 (-)Ensembl
RefSeq Acc Id: NM_001134643   ⟹   NP_001128115
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,329,497 - 31,891,281 (-)NCBI
mRatBN7.2923,833,087 - 24,394,880 (-)NCBI
Rnor_6.0927,565,869 - 28,141,114 (-)NCBI
Rnor_5.0926,413,162 - 26,986,457 (-)NCBI
Celera921,408,169 - 21,967,095 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083094   ⟹   XP_038939022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,326,595 - 31,892,376 (-)NCBI
mRatBN7.2923,830,185 - 24,395,887 (-)NCBI
RefSeq Acc Id: XM_039083095   ⟹   XP_038939023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,326,595 - 31,892,377 (-)NCBI
mRatBN7.2923,830,185 - 24,395,887 (-)NCBI
RefSeq Acc Id: XM_039083097   ⟹   XP_038939025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8931,404,772 - 31,892,399 (-)NCBI
mRatBN7.2923,906,602 - 24,395,984 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001128115   ⟸   NM_001134643
- UniProtKB: F1LY25 (UniProtKB/TrEMBL),   A6JJ99 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018552   ⟸   ENSRNOT00000018552
RefSeq Acc Id: ENSRNOP00000047562   ⟸   ENSRNOT00000040034
RefSeq Acc Id: XP_038939023   ⟸   XM_039083095
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNI9 (UniProtKB/TrEMBL),   A6JJ99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939022   ⟸   XM_039083094
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZXW9 (UniProtKB/TrEMBL),   A6JJ99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939025   ⟸   XM_039083097
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000084442   ⟸   ENSRNOT00000106244
RefSeq Acc Id: ENSRNOP00000079928   ⟸   ENSRNOT00000097073
RefSeq Acc Id: ENSRNOP00000097404   ⟸   ENSRNOT00000098049
Protein Domains
Ion transport   Potassium channel voltage dependent KCNQ C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LY25-F1-model_v2 AlphaFold F1LY25 1-821 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628848 AgrOrtholog
BioCyc Gene G2FUF-27994 BioCyc
Ensembl Genes ENSRNOG00000013781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018552 ENTREZGENE
  ENSRNOT00000018552.9 UniProtKB/TrEMBL
  ENSRNOT00000097073.1 UniProtKB/TrEMBL
  ENSRNOT00000098049.1 UniProtKB/TrEMBL
  ENSRNOT00000106244.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  6.10.140.1910 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_KCNQ UniProtKB/TrEMBL
  K_chnl_volt-dep_KCNQ_C UniProtKB/TrEMBL
KEGG Report rno:259273 UniProtKB/TrEMBL
NCBI Gene 259273 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 UniProtKB/TrEMBL
  POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
  KCNQ_channel UniProtKB/TrEMBL
PhenoGen Kcnq5 PhenoGen
PRINTS KCHANNEL UniProtKB/TrEMBL
  KCNQCHANNEL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013781 RatGTEx
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8I5ZNI9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AWB8_RAT UniProtKB/TrEMBL
  A6JJ99 ENTREZGENE, UniProtKB/TrEMBL
  F1LY25 ENTREZGENE, UniProtKB/TrEMBL
  Q8K3W7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Kcnq5  potassium voltage-gated channel subfamily Q member 5  Kcnq5  potassium channel, voltage-gated KQT-like subfamily Q, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-26 Kcnq5  potassium channel, voltage-gated KQT-like subfamily Q, member 5  Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-18 Kcnq5l  potassium voltage-gated channel, subfamily Q, member 5-like  Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Data merged from RGD:1596181 737654 APPROVED
2012-07-18 Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Kcnq5l  potassium voltage-gated channel, subfamily Q, member 5-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5  Kcnq5  potassium voltage-gated channel, subfamily Q, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Kcnq5l  potassium voltage-gated channel, subfamily Q, member 5-like  Kcnq5  potassium voltage-gated channel, subfamily Q, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Kcnq5  potassium voltage-gated channel, subfamily Q, member 5  LOC689123  similar to Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel alpha subunit KvLQT5) (KQT-like 5)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC689123  similar to Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel alpha subunit KvLQT5) (KQT-like 5)      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Kcnq5  potassium voltage-gated channel, subfamily Q, member 5    potassium voltage-gated channel, KQT-like subfamily, member 5  Name updated 1299863 APPROVED
2003-02-27 Kcnq5  potassium voltage-gated channel, KQT-like subfamily, member 5      Symbol and Name status set to provisional 70820 PROVISIONAL