Gene: Il12b (interleukin 12B) Rattus norvegicus
Symbol: Il12b
Name: interleukin 12B
Description: ENCODES a protein that exhibits interleukin-12 alpha subunit binding; protein heterodimerization activity; cytokine activity (ortholog); INVOLVED IN natural killer cell activation involved in immune response; sensory perception of pain; cell cycle arrest (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; ASSOCIATED WITH Encephalomyelitis, Autoimmune, Experimental; Sepsis; Asthma (ortholog); FOUND IN extracellular space; interleukin-12 complex; cytoplasm (ortholog); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Il12; Interleukin 12; interleukin-12 p40; interleukin-12 p40 precursor; interleukin-12 subunit beta
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01030,034,447 - 30,048,774 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01029,868,367 - 29,882,535 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41029,558,955 - 29,568,331 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11029,560,003 - 29,569,378 (+)NCBI
Celera1028,372,232 - 28,381,601 (+)NCBI
Cytogenetic Map10q21NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Il12b
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 628704
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2016-09-20
Status: ACTIVE