Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of MXD3 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of MXD3 mRNA | CTD | PMID:17351261 | 17beta-estradiol | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of MXD3 mRNA | CTD | PMID:23019147 and PMID:31614463 | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of MXD3 mRNA | CTD | PMID:32145629 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MXD3 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MXD3 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MXD3 mRNA | CTD | PMID:27913140 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mxd3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MXD3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MXD3 mRNA | CTD | PMID:19684285 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | MXD3 (Homo sapiens) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MXD3 mRNA | CTD | PMID:19684285 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Mxd3 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of MXD3 mRNA | CTD | PMID:25172293 | 3H-1,2-dithiole-3-thione | increases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in increased expression of MXD3 mRNA | CTD | PMID:19162173 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Mxd3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of MXD3 mRNA | CTD | PMID:18648102 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of MXD3 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of MXD3 mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | MXD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of MXD3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of MXD3 mRNA | CTD | PMID:32699268 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of MXD3 mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of MXD3 mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of MXD3 mRNA | CTD | PMID:23630614 | aflatoxin B1 | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of MXD3 mRNA | CTD | PMID:32234424 | all-trans-retinoic acid | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of MXD3 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | MXD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of MXD3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of MXD3 mRNA | CTD | PMID:32699268 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of MXD3 mRNA | CTD | PMID:16483693 | arsane | affects expression | ISO | MXD3 (Homo sapiens) | 6480464 | Arsenic affects the expression of MXD3 mRNA | CTD | PMID:18414638 | arsenic atom | affects expression | ISO | MXD3 (Homo sapiens) | 6480464 | Arsenic affects the expression of MXD3 mRNA | CTD | PMID:18414638 | benzo[a]pyrene | increases methylation | ISO | MXD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MXD3 3' UTR | CTD | PMID:27901495 | benzo[b]fluoranthene | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of MXD3 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MXD3 mRNA | CTD | PMID:25181051 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MXD3 mRNA | CTD | PMID:32145629 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MXD3 mRNA | CTD | PMID:30816183 | butanal | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of MXD3 mRNA | CTD | PMID:26079696 | calcitriol | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of MXD3 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | MXD3 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of MXD3 mRNA | CTD | PMID:21592394 | carbon nanotube | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | clobetasol | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Clobetasol results in increased expression of MXD3 mRNA | CTD | PMID:27462272 | clofibrate | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of MXD3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MXD3 mRNA] | CTD | PMID:17585979 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of MXD3 mRNA | CTD | PMID:24386269 | curcumin | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Curcumin results in decreased expression of MXD3 mRNA | CTD | PMID:15713895 and PMID:17198877 | cycloheximide | multiple interactions | ISO | MXD3 (Homo sapiens) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MXD3 mRNA | CTD | PMID:19684285 | cyclosporin A | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MXD3 mRNA | CTD | PMID:25562108 | cytarabine | increases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Cytarabine results in increased expression of MXD3 mRNA | CTD | PMID:21198554 | diallyl trisulfide | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | diallyl trisulfide results in decreased expression of MXD3 mRNA | CTD | PMID:34995734 | diazinon | increases methylation | ISO | MXD3 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of MXD3 gene | CTD | PMID:22964155 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of MXD3 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of MXD3 mRNA | CTD | PMID:17361019 and PMID:21266533 | dicrotophos | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of MXD3 mRNA | CTD | PMID:28302478 | dimethylarsinic acid | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of MXD3 mRNA | CTD | PMID:34876320 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of MXD3 mRNA | CTD | PMID:25539665 | lidocaine | increases expression | EXP | | 6480464 | Lidocaine results in increased expression of MXD3 mRNA | CTD | PMID:35283115 | methylarsonic acid | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of MXD3 mRNA | CTD | PMID:34876320 | N-Nitrosopyrrolidine | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of MXD3 mRNA | CTD | PMID:32234424 | naphthalene | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | naphthalene results in increased expression of MXD3 mRNA | CTD | PMID:18978301 | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of MXD3 mRNA | CTD | PMID:25729387 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MXD3 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | MXD3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of MXD3 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | ozone | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Ozone results in increased expression of MXD3 mRNA | CTD | PMID:33026818 | ozone | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of MXD3 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of MXD3 mRNA | CTD | PMID:27106289 and PMID:34911549 | paracetamol | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of MXD3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MXD3 mRNA] | CTD | PMID:17585979 | PCB138 | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | perfluorooctanoic acid | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of MXD3 mRNA | CTD | PMID:36326898 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of MXD3 mRNA | CTD | PMID:22698814 | propanal | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of MXD3 mRNA | CTD | PMID:26079696 | silicon dioxide | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of MXD3 mRNA | CTD | PMID:29341224 | silver atom | decreases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Silver results in decreased expression of MXD3 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Silver results in decreased expression of MXD3 mRNA | CTD | PMID:27131904 | sodium arsenate | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of MXD3 mRNA | CTD | PMID:34876320 | sodium arsenite | decreases expression | ISO | Mxd3 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of MXD3 mRNA | CTD | PMID:17998272 | sodium arsenite | multiple interactions | ISO | Mxd3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of MXD3 mRNA | CTD | PMID:34876320 | sodium arsenite | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of MXD3 mRNA | CTD | PMID:34032870 | styrene | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | Styrene results in increased expression of MXD3 mRNA | CTD | PMID:28951217 | sunitinib | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MXD3 mRNA | CTD | PMID:31533062 | testosterone | multiple interactions | ISO | MXD3 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of MXD3 mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of MXD3 mRNA | CTD | PMID:21592394 | titanium dioxide | decreases methylation | ISO | MXD3 (Homo sapiens) | 6480464 | titanium dioxide results in decreased methylation of MXD3 gene | CTD | PMID:34973136 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MXD3 mRNA | CTD | PMID:25729387 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of MXD3 mRNA | CTD | PMID:25729387 | trimellitic anhydride | increases expression | ISO | Mxd3 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of MXD3 mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | troglitazone results in decreased expression of MXD3 mRNA | CTD | PMID:19140230 | trovafloxacin | decreases expression | ISO | Mxd3 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of MXD3 mRNA | CTD | PMID:35537566 | valproic acid | decreases expression | ISO | MXD3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MXD3 mRNA | CTD | PMID:23527032 | |