Stau1 (staufen double-stranded RNA binding protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Stau1 (staufen double-stranded RNA binding protein 1) Rattus norvegicus
Analyze
Symbol: Stau1
Name: staufen double-stranded RNA binding protein 1
RGD ID: 621778
Description: Enables double-stranded RNA binding activity and protein phosphatase 1 binding activity. Involved in cellular response to oxidative stress; modification of postsynaptic structure; and positive regulation of long-term synaptic potentiation. Located in neuronal cell body. Is active in glutamatergic synapse. Orthologous to human STAU1 (staufen double-stranded RNA binding protein 1); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: double-stranded RNA-binding protein Staufen homolog 1; MGC124588; Stau; staufen (Drosophila, RNA-binding protein); staufen RNA binding protein homolog 1; staufen RNA binding protein homolog 1 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83176,099,053 - 176,144,947 (-)NCBIGRCr8
mRatBN7.23155,680,000 - 155,725,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3155,680,000 - 155,725,909 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3159,481,477 - 159,527,221 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03167,980,447 - 168,026,194 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03165,722,139 - 165,767,900 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03163,703,204 - 163,748,996 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3163,703,204 - 163,748,996 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03169,863,711 - 169,909,847 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43158,101,209 - 158,147,105 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13158,007,244 - 158,053,128 (-)NCBI
Celera3154,261,496 - 154,307,216 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The mammalian staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: implications for its involvement in mRNA transport. Kiebler MA, etal., J Neurosci 1999 Jan 1;19(1):288-97.
4. Staufen 2 regulates mGluR long-term depression and Map1b mRNA distribution in hippocampal neurons. Lebeau G, etal., Learn Mem. 2011 Apr 20;18(5):314-26. doi: 10.1101/lm.2100611. Print 2011.
5. mRNA binding protein staufen 1-dependent regulation of pyramidal cell spine morphology via NMDA receptor-mediated synaptic plasticity. Lebeau G, etal., Mol Brain. 2011 Jun 2;4:22. doi: 10.1186/1756-6606-4-22.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Two rat brain staufen isoforms differentially bind RNA. Monshausen M, etal., J Neurochem 2001 Jan;76(1):155-65.
8. The RNA-binding protein Staufen from rat brain interacts with protein phosphatase-1. Monshausen M, etal., J Neurochem. 2002 May;81(3):557-64.
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14. Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes. Thomas MG, etal., Mol Biol Cell. 2005 Jan;16(1):405-20. Epub 2004 Nov 3.
15. Aberrantly Methylated-Differentially Expressed Genes Identify Novel Atherosclerosis Risk Subtypes. Xue Y, etal., Front Genet. 2020 Dec 14;11:569572. doi: 10.3389/fgene.2020.569572. eCollection 2020.
Additional References at PubMed
PMID:12843282   PMID:15121898   PMID:15312650   PMID:18316402   PMID:19029303   PMID:19193871   PMID:19199708   PMID:19825938   PMID:19946888   PMID:22681889   PMID:22978549   PMID:23106098  
PMID:23907398   PMID:34022264  


Genomics

Comparative Map Data
Stau1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83176,099,053 - 176,144,947 (-)NCBIGRCr8
mRatBN7.23155,680,000 - 155,725,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3155,680,000 - 155,725,909 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3159,481,477 - 159,527,221 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03167,980,447 - 168,026,194 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03165,722,139 - 165,767,900 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03163,703,204 - 163,748,996 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3163,703,204 - 163,748,996 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03169,863,711 - 169,909,847 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43158,101,209 - 158,147,105 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13158,007,244 - 158,053,128 (-)NCBI
Celera3154,261,496 - 154,307,216 (-)NCBICelera
Cytogenetic Map3q42NCBI
STAU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382049,113,339 - 49,219,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2049,113,339 - 49,188,367 (-)EnsemblGRCh38hg38GRCh38
GRCh372047,729,876 - 47,835,832 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362047,163,283 - 47,238,311 (-)NCBINCBI36Build 36hg18NCBI36
Build 342047,163,467 - 47,238,311NCBI
Celera2044,434,510 - 44,509,526 (-)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2044,479,031 - 44,553,753 (-)NCBIHuRef
CHM1_12047,633,937 - 47,708,944 (-)NCBICHM1_1
T2T-CHM13v2.02050,882,825 - 50,988,811 (-)NCBIT2T-CHM13v2.0
Stau1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392166,789,469 - 166,838,253 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2166,789,469 - 166,838,219 (-)EnsemblGRCm39 Ensembl
GRCm382166,947,549 - 166,996,315 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2166,947,549 - 166,996,299 (-)EnsemblGRCm38mm10GRCm38
MGSCv372166,773,641 - 166,821,778 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362166,639,478 - 166,687,504 (-)NCBIMGSCv36mm8
Celera2172,887,550 - 172,935,664 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map287.22NCBI
Stau1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554458,971,585 - 9,003,647 (+)NCBIChiLan1.0ChiLan1.0
STAU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22154,856,184 - 54,930,060 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12054,849,291 - 54,923,169 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02045,452,639 - 45,526,512 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12046,517,772 - 46,581,524 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2046,517,772 - 46,578,024 (-)Ensemblpanpan1.1panPan2
STAU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12435,816,224 - 35,868,791 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2435,817,664 - 35,860,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2435,059,029 - 35,113,351 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02436,520,996 - 36,575,325 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2436,521,000 - 36,575,346 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12435,762,100 - 35,816,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02435,896,079 - 35,950,349 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02436,437,137 - 36,491,471 (-)NCBIUU_Cfam_GSD_1.0
Stau1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640189,595,190 - 189,649,850 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365145,058,692 - 5,103,528 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365145,058,682 - 5,103,493 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1750,804,962 - 50,869,223 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11750,804,959 - 50,903,155 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21757,265,267 - 57,282,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STAU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1214,804,750 - 14,879,067 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl214,804,791 - 14,878,838 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605063,300,287 - 63,379,235 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stau1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247906,172,762 - 6,229,487 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247906,173,160 - 6,229,487 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Stau1
205 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:120
Interacting mature miRNAs:135
Transcripts:ENSRNOT00000010633
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat

Markers in Region
RH128700  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23155,680,057 - 155,680,225 (+)MAPPERmRatBN7.2
Rnor_6.03163,703,262 - 163,703,429NCBIRnor6.0
Rnor_5.03169,863,769 - 169,863,936UniSTSRnor5.0
RGSC_v3.43158,101,267 - 158,101,434UniSTSRGSC3.4
Celera3154,261,554 - 154,261,721UniSTS
RH 3.4 Map21241.2UniSTS
Cytogenetic Map3q42UniSTS
RH138783  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23155,680,889 - 155,681,066 (+)MAPPERmRatBN7.2
Rnor_6.03163,704,094 - 163,704,270NCBIRnor6.0
Rnor_5.03169,864,601 - 169,864,777UniSTSRnor5.0
RGSC_v3.43158,102,099 - 158,102,275UniSTSRGSC3.4
Celera3154,262,386 - 154,262,562UniSTS
RH 3.4 Map31471.1UniSTS
Cytogenetic Map3q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 57 41 19 41 5 8 74 35 41 11 5
Low 1 3 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010633   ⟹   ENSRNOP00000010633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3155,680,000 - 155,725,909 (-)Ensembl
Rnor_6.0 Ensembl3163,703,204 - 163,748,996 (-)Ensembl
RefSeq Acc Id: NM_001109907   ⟹   NP_001103377
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83176,099,053 - 176,144,947 (-)NCBI
mRatBN7.23155,680,000 - 155,725,909 (-)NCBI
Rnor_6.03163,703,204 - 163,748,996 (-)NCBI
Rnor_5.03169,863,711 - 169,909,847 (-)NCBI
RGSC_v3.43158,101,209 - 158,147,105 (-)RGD
Celera3154,261,496 - 154,307,216 (-)RGD
Sequence:
RefSeq Acc Id: NM_053436   ⟹   NP_445888
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83176,099,053 - 176,144,947 (-)NCBI
mRatBN7.23155,680,000 - 155,725,909 (-)NCBI
Rnor_6.03163,703,204 - 163,748,996 (-)NCBI
Rnor_5.03169,863,711 - 169,909,847 (-)NCBI
RGSC_v3.43158,101,209 - 158,147,105 (-)RGD
Celera3154,261,496 - 154,307,216 (-)RGD
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_445888   ⟸   NM_053436
- Peptide Label: isoform 1
- UniProtKB: Q66HP4 (UniProtKB/TrEMBL),   Q9ET50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103377   ⟸   NM_001109907
- Peptide Label: isoform 2
- UniProtKB: Q66HP4 (UniProtKB/TrEMBL),   Q9ESY8 (UniProtKB/TrEMBL),   Q3T1L2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010633   ⟸   ENSRNOT00000010633
Protein Domains
DRBM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ET50-F1-model_v2 AlphaFold Q9ET50 1-495 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692687
Promoter ID:EPDNEW_R3212
Type:multiple initiation site
Name:Stau1_1
Description:staufen double-stranded RNA binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03163,749,022 - 163,749,082EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621778 AgrOrtholog
BioCyc Gene G2FUF-46758 BioCyc
Ensembl Genes ENSRNOG00000007781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010633 ENTREZGENE
  ENSRNOT00000010633.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.160.20 UniProtKB/TrEMBL
  6.10.250.1360 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7124595 IMAGE-MGC_LOAD
  IMAGE:7937343 IMAGE-MGC_LOAD
InterPro dsRNA-bd-like UniProtKB/TrEMBL
  STAU1_DSRM_3 UniProtKB/TrEMBL
  Staufen_C UniProtKB/TrEMBL
KEGG Report rno:84496 UniProtKB/TrEMBL
MGC_CLONE MGC:124588 IMAGE-MGC_LOAD
  MGC:93303 IMAGE-MGC_LOAD
NCBI Gene 84496 ENTREZGENE
PANTHER DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1 UniProtKB/TrEMBL
  MATERNAL EFFECT PROTEIN STAUFEN UniProtKB/TrEMBL
Pfam dsrm UniProtKB/TrEMBL
  Staufen_C UniProtKB/TrEMBL
PhenoGen Stau1 PhenoGen
PROSITE DS_RBD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007781 RatGTEx
SMART DSRM UniProtKB/TrEMBL
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/TrEMBL
UniProt Q3T1L2 ENTREZGENE, UniProtKB/TrEMBL
  Q66HP4 ENTREZGENE, UniProtKB/TrEMBL
  Q9ESY8 ENTREZGENE, UniProtKB/TrEMBL
  Q9ET50 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-14 Stau1  staufen double-stranded RNA binding protein 1  Stau1  staufen RNA binding protein homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Stau1  staufen RNA binding protein homolog 1 (Drosophila)  Stau  staufen (Drosophila, RNA-binding protein)  Symbol and Name updated 1299863 APPROVED
2002-08-07 Stau  staufen (Drosophila, RNA-binding protein)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains has four double-stranded RNA-binding domains 634222
gene_process regulates subcellular localization of dendritic microtubular cytoskeleton 634222