Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Body Weight | | ISO | SEC16B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:22344219 and PMID:22344221 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Body Weight | | ISO | SEC16B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:22344219 and PMID:22344221 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. | Misawa H and Yamaguchi M, Int J Mol Med 2001 Nov;8(5):513-20. |
3. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
6. | Novel protein RGPR-p117: the gene expression in physiologic state and the binding activity to regucalcin gene promoter region in rat liver. | Yamaguchi M, etal., J Cell Biochem 2003 Apr 15;88(6):1092-100. |
PMID:16211248 | PMID:16273285 | PMID:16676356 | PMID:17549392 | PMID:17786289 | PMID:21478858 | PMID:21768384 | PMID:22355596 | PMID:35835253 |
Sec16b (Rattus norvegicus - Norway rat) |
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SEC16B (Homo sapiens - human) |
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Sec16b (Mus musculus - house mouse) |
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Sec16b (Chinchilla lanigera - long-tailed chinchilla) |
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SEC16B (Pan paniscus - bonobo/pygmy chimpanzee) |
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SEC16B (Canis lupus familiaris - dog) |
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Sec16b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SEC16B (Sus scrofa - pig) |
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LOC103230534 (Chlorocebus sabaeus - green monkey) |
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Sec16b (Heterocephalus glaber - naked mole-rat) |
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Variants in Sec16b
490 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
BE108065 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 2 | 2 | 31 | 31 | 31 | 3 | 5 | ||||||
Low | 1 | 41 | 26 | 10 | 19 | 10 | 8 | 11 | 74 | 32 | 36 | 11 | 8 |
Below cutoff |
RefSeq Transcripts | NM_053571 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_008769682 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008769685 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008769686 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598948 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598949 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598950 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017598951 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039091144 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039091145 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039091147 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272652 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272653 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272654 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272655 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272656 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272657 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272658 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272659 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272660 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB060653 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AB178524 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473958 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000007321 ⟹ ENSRNOP00000007321 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000044008 ⟹ ENSRNOP00000046286 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_053571 ⟹ NP_446023 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039091144 ⟹ XP_038947072 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039091145 ⟹ XP_038947073 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039091147 ⟹ XP_038947075 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063272652 ⟹ XP_063128722 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272653 ⟹ XP_063128723 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272654 ⟹ XP_063128724 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272655 ⟹ XP_063128725 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272656 ⟹ XP_063128726 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272657 ⟹ XP_063128727 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272658 ⟹ XP_063128728 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272659 ⟹ XP_063128729 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272660 ⟹ XP_063128730 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_446023 | (Get FASTA) | NCBI Sequence Viewer |
XP_038947072 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038947073 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038947075 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128722 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128723 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128724 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128725 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128726 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128727 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128728 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128729 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128730 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | BAB43905 | (Get FASTA) | NCBI Sequence Viewer |
BAD18068 | (Get FASTA) | NCBI Sequence Viewer | |
EDM09463 | (Get FASTA) | NCBI Sequence Viewer | |
EDM09464 | (Get FASTA) | NCBI Sequence Viewer | |
EDM09465 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000046286 | ||
ENSRNOP00000046286.3 | |||
GenBank Protein | Q75N33 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_446023 ⟸ NM_053571 |
- UniProtKB: | Q75N33 (UniProtKB/Swiss-Prot), Q925T1 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000007321 ⟸ ENSRNOT00000007321 |
RefSeq Acc Id: | ENSRNOP00000046286 ⟸ ENSRNOT00000044008 |
RefSeq Acc Id: | XP_038947072 ⟸ XM_039091144 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038947073 ⟸ XM_039091145 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038947075 ⟸ XM_039091147 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A6ID32 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063128722 ⟸ XM_063272652 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128728 ⟸ XM_063272658 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q925T1 (UniProtKB/Swiss-Prot), Q75N33 (UniProtKB/Swiss-Prot) |
RefSeq Acc Id: | XP_063128730 ⟸ XM_063272660 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063128723 ⟸ XM_063272653 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128724 ⟸ XM_063272654 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128725 ⟸ XM_063272655 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128726 ⟸ XM_063272656 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128727 ⟸ XM_063272657 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063128729 ⟸ XM_063272659 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q925T1 (UniProtKB/Swiss-Prot), Q75N33 (UniProtKB/Swiss-Prot) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q75N33-F1-model_v2 | AlphaFold | Q75N33 | 1-1057 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13698922 | ||||||||
Promoter ID: | EPDNEW_R9447 | ||||||||
Type: | initiation region | ||||||||
Name: | Sec16b_1 | ||||||||
Description: | SEC16 homolog B, endoplasmic reticulum export factor | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:621658 | AgrOrtholog |
BioCyc Gene | G2FUF-17791 | BioCyc |
Ensembl Genes | ENSRNOG00000005229 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
Ensembl Transcript | ENSRNOT00000044008 | ENTREZGENE |
ENSRNOT00000044008.6 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 1.25.40.1030 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | ACE1_Sec16_Sec31 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Sec16 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Sec16_CCD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:89868 | UniProtKB/Swiss-Prot |
NCBI Gene | 89868 | ENTREZGENE |
PANTHER | PROTEIN TRANSPORT PROTEIN SEC16B | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR13402 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Sec16 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Sec16_C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Sec16b | PhenoGen |
RatGTEx | ENSRNOG00000005229 | RatGTEx |
UniProt | A6ID32 | ENTREZGENE, UniProtKB/TrEMBL |
Q75N33 | ENTREZGENE | |
Q925T1 | ENTREZGENE | |
SC16B_RAT | UniProtKB/Swiss-Prot | |
UniProt Secondary | Q925T1 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2015-07-30 | Sec16b | SEC16 homolog B, endoplasmic reticulum export factor | Sec16b | SEC16 homolog B (S. cerevisiae) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-02-25 | Sec16b | SEC16 homolog B (S. cerevisiae) | Lztr2 | leucine zipper transcription regulator 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2006-03-30 | Lztr2 | leucine zipper transcription regulator 2 | Rgpr | regucalcin gene promotor region related protein | Symbol and Name updated | 1299863 | APPROVED |
2004-02-26 | Rgpr | regucalcin gene promotor region related protein | Symbol and Name status set to approved | 625702 | APPROVED | ||
2002-08-07 | Rgpr | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_homology | has greater than 70% identity to human and mouse homologs | 633817 |