Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-pilocarpine | increases expression | EXP | | 6480464 | Pilocarpine results in increased expression of NOVA1 mRNA | CTD | PMID:20470870 | (+)-pilocarpine | multiple interactions | EXP | | 6480464 | Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NOVA1 mRNA] | CTD | PMID:20470870 | 17beta-estradiol | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of NOVA1 mRNA | CTD | PMID:18692832 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Nova1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Nova1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NOVA1 mRNA | CTD | PMID:21296121 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NOVA1 mRNA | CTD | PMID:32109520 and PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of NOVA1 mRNA | CTD | PMID:22298810 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Nova1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of NOVA1 mRNA | CTD | PMID:20188158 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Nova1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of NOVA1 mRNA | CTD | PMID:28973697 | aflatoxin B1 | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of NOVA1 mRNA | CTD | PMID:27153756 | aflatoxin B1 | decreases methylation | ISO | NOVA1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of NOVA1 promoter | CTD | PMID:30157460 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of NOVA1 mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of NOVA1 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NOVA1 mRNA | CTD | PMID:33212167 | arsenite(3-) | increases methylation | ISO | NOVA1 (Homo sapiens) | 6480464 | arsenite results in increased methylation of NOVA1 promoter | CTD | PMID:23974009 | arsenous acid | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of NOVA1 mRNA | CTD | PMID:20458559 | benzo[a]pyrene | increases methylation | ISO | NOVA1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of NOVA1 5' UTR and Benzo(a)pyrene results in increased methylation of NOVA1 exon | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | NOVA1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of NOVA1 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | NOVA1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of NOVA1 promoter | CTD | PMID:27901495 | beryllium sulfate | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | beryllium sulfate results in increased expression of NOVA1 mRNA | CTD | PMID:16314022 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of NOVA1 mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NOVA1 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of NOVA1 gene | CTD | PMID:28505145 | butanal | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of NOVA1 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NOVA1 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NOVA1 mRNA | CTD | PMID:35301059 | cisplatin | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of NOVA1 mRNA | CTD | PMID:27392435 | clobetasol | decreases expression | ISO | Nova1 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of NOVA1 mRNA | CTD | PMID:27462272 | copper(II) sulfate | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of NOVA1 mRNA | CTD | PMID:19549813 | cytarabine | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Cytarabine results in increased expression of NOVA1 mRNA | CTD | PMID:21198554 | dexamethasone | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of NOVA1 mRNA | CTD | PMID:25047013 | diarsenic trioxide | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of NOVA1 mRNA | CTD | PMID:20458559 | diclofenac | decreases expression | ISO | Nova1 (Mus musculus) | 6480464 | Diclofenac results in decreased expression of NOVA1 mRNA | CTD | PMID:26934552 | dorsomorphin | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | entinostat | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of NOVA1 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NOVA1 mRNA | CTD | PMID:27188386 | ethanol | affects splicing | ISO | Nova1 (Mus musculus) | 6480464 | Ethanol affects the splicing of NOVA1 mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | Nova1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of NOVA1 mRNA | CTD | PMID:25629700 | genistein | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of NOVA1 gene | CTD | PMID:28505145 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of NOVA1 mRNA | CTD | PMID:33387578 | hydralazine | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of NOVA1 mRNA | CTD | PMID:17183730 | lead(0) | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Lead results in decreased expression of NOVA1 mRNA | CTD | PMID:19921347 | lead(0) | affects splicing | ISO | NOVA1 (Homo sapiens) | 6480464 | Lead affects the splicing of NOVA1 mRNA | CTD | PMID:28903495 | maneb | multiple interactions | ISO | Nova1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of NOVA1 mRNA | CTD | PMID:36117858 | miconazole | decreases expression | ISO | Nova1 (Mus musculus) | 6480464 | Miconazole results in decreased expression of NOVA1 mRNA | CTD | PMID:27462272 | mifepristone | increases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Mifepristone results in increased expression of NOVA1 mRNA | CTD | PMID:17584828 | Muraglitazar | increases expression | EXP | | 6480464 | muraglitazar results in increased expression of NOVA1 mRNA | CTD | PMID:21515302 | N-methyl-4-phenylpyridinium | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of NOVA1 mRNA | CTD | PMID:24810058 | nickel sulfate | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of NOVA1 mRNA | CTD | PMID:22714537 | ozone | multiple interactions | ISO | Nova1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of NOVA1 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NOVA1 mRNA | CTD | PMID:22230336 | paraquat | multiple interactions | ISO | Nova1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of NOVA1 mRNA | CTD | PMID:36117858 | PCB138 | multiple interactions | ISO | Nova1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | pirinixic acid | increases expression | ISO | Nova1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NOVA1 mRNA | CTD | PMID:20813756 | SB 431542 | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | scopolamine | multiple interactions | EXP | | 6480464 | Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NOVA1 mRNA] | CTD | PMID:20470870 | sevoflurane | increases expression | EXP | | 6480464 | Sevoflurane results in increased expression of NOVA1 mRNA and Sevoflurane results in increased expression of NOVA1 protein | CTD | PMID:35110470 | silicon dioxide | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of NOVA1 mRNA | CTD | PMID:25895662 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of NOVA1 mRNA | CTD | PMID:19281266 | tamoxifen | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Tamoxifen results in decreased expression of NOVA1 mRNA | CTD | PMID:15590111 | temozolomide | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of NOVA1 mRNA | CTD | PMID:31758290 | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of NOVA1 mRNA | CTD | PMID:21515302 | testosterone | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of NOVA1 mRNA | CTD | PMID:33359661 | trichostatin A | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of NOVA1 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NOVA1 mRNA | CTD | PMID:27188386 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of NOVA1 mRNA | CTD | PMID:21515302 | valproic acid | decreases methylation | ISO | NOVA1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of NOVA1 gene | CTD | PMID:29154799 | valproic acid | multiple interactions | ISO | NOVA1 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of NOVA1 mRNA more ... | CTD | PMID:17183730 and PMID:27188386 | valproic acid | affects expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NOVA1 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NOVA1 mRNA | CTD | PMID:23179753 more ... | vitamin E | decreases expression | ISO | NOVA1 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of NOVA1 mRNA | CTD | PMID:19244175 | |