Nova1 (NOVA alternative splicing regulator 1) - Rat Genome Database

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Gene: Nova1 (NOVA alternative splicing regulator 1) Rattus norvegicus
Analyze
Symbol: Nova1
Name: NOVA alternative splicing regulator 1
RGD ID: 621345
Description: Predicted to enable mRNA 3'-UTR binding activity and sequence-specific mRNA binding activity. Involved in regulation of mRNA processing and spinal cord development. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human NOVA1 (NOVA alternative splicing regulator 1); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neuro-oncological ventral antigen 1; Nova-1; RNA-binding protein Nova-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8669,506,983 - 69,632,437 (-)NCBIGRCr8
mRatBN7.2663,780,105 - 63,905,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl663,783,489 - 63,906,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx664,171,614 - 64,293,460 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0664,486,772 - 64,608,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0663,933,525 - 64,055,455 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0666,960,126 - 67,085,836 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl666,963,510 - 67,085,390 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0676,535,375 - 76,660,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4666,193,472 - 66,320,240 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1666,202,073 - 66,323,082 (-)NCBI
Celera662,747,220 - 62,869,241 (-)NCBICelera
Cytogenetic Map6q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
mRNA 3'-UTR binding  (IEA,ISO)
mRNA binding  (IBA,IEA,ISO,ISS)
protein binding  (ISO)
RNA binding  (ISO,ISS)
sequence-specific mRNA binding  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Role of Nova-1 in regulating alpha2N, a novel glycine receptor splice variant, in developing spinal cord neurons. Kumar DV, etal., J Neurobiol 2002 Aug;52(2):156-65.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. An alternative splicing program promotes adipose tissue thermogenesis. Vernia S, etal., Elife. 2016 Sep 16;5. doi: 10.7554/eLife.17672.
Additional References at PubMed
PMID:10719891   PMID:22681889   PMID:23042482   PMID:23359859   PMID:25249621   PMID:26105073   PMID:27378374   PMID:28791345   PMID:33799408  


Genomics

Comparative Map Data
Nova1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8669,506,983 - 69,632,437 (-)NCBIGRCr8
mRatBN7.2663,780,105 - 63,905,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl663,783,489 - 63,906,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx664,171,614 - 64,293,460 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0664,486,772 - 64,608,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0663,933,525 - 64,055,455 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0666,960,126 - 67,085,836 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl666,963,510 - 67,085,390 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0676,535,375 - 76,660,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4666,193,472 - 66,320,240 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1666,202,073 - 66,323,082 (-)NCBI
Celera662,747,220 - 62,869,241 (-)NCBICelera
Cytogenetic Map6q21NCBI
NOVA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381426,443,090 - 26,598,033 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1426,443,090 - 26,598,033 (-)EnsemblGRCh38hg38GRCh38
GRCh371426,912,296 - 27,067,239 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361425,984,929 - 26,136,800 (-)NCBINCBI36Build 36hg18NCBI36
Build 341426,009,163 - 26,136,800NCBI
Celera146,779,476 - 6,931,361 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef147,031,090 - 7,190,872 (-)NCBIHuRef
CHM1_11426,913,753 - 27,065,665 (-)NCBICHM1_1
T2T-CHM13v2.01420,640,973 - 20,795,930 (-)NCBIT2T-CHM13v2.0
Nova1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391246,744,678 - 46,866,143 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1246,741,300 - 46,865,712 (-)EnsemblGRCm39 Ensembl
GRCm381246,697,895 - 46,819,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1246,694,517 - 46,818,929 (-)EnsemblGRCm38mm10GRCm38
MGSCv371247,795,504 - 47,919,762 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361247,570,474 - 47,694,732 (-)NCBIMGSCv36mm8
Celera1248,021,874 - 48,146,837 (-)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1221.46NCBI
Nova1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540933,680,587 - 33,815,818 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540933,681,947 - 33,820,356 (+)NCBIChiLan1.0ChiLan1.0
NOVA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21527,772,225 - 27,924,686 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11426,988,723 - 27,140,162 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0147,193,308 - 7,345,535 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11425,314,077 - 25,466,715 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1425,314,077 - 25,466,861 (-)Ensemblpanpan1.1panPan2
NOVA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.186,133,608 - 6,281,508 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl86,135,679 - 6,281,384 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha86,052,438 - 6,201,930 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.086,227,890 - 6,377,452 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl86,229,520 - 6,377,483 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.185,918,471 - 6,068,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.085,989,071 - 6,138,587 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.086,257,436 - 6,406,949 (-)NCBIUU_Cfam_GSD_1.0
Nova1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864038,211,656 - 38,347,469 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364941,717,268 - 1,853,430 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364941,720,030 - 1,853,177 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOVA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl772,805,230 - 72,961,258 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1772,805,138 - 72,961,257 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2778,002,491 - 78,041,732 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NOVA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1243,363,652 - 3,513,901 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl243,360,831 - 3,514,435 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603615,126,163 - 15,276,533 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nova1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248205,821,477 - 5,971,637 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248205,821,232 - 5,973,709 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nova1
970 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:117
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000050372
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)66304056271636266Rat

Markers in Region
NOVA1__6065  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2663,783,483 - 63,784,096 (+)MAPPERmRatBN7.2
Rnor_6.0666,963,505 - 66,964,117NCBIRnor6.0
Rnor_5.0676,538,754 - 76,539,366UniSTSRnor5.0
RGSC_v3.4666,196,851 - 66,197,463UniSTSRGSC3.4
Celera662,747,215 - 62,747,827UniSTS
Cytogenetic Map6q21UniSTS
Nova1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2663,785,955 - 63,786,495 (+)MAPPERmRatBN7.2
Rnor_6.0666,965,977 - 66,966,516NCBIRnor6.0
Rnor_5.0676,541,226 - 76,541,765UniSTSRnor5.0
RGSC_v3.4666,199,323 - 66,199,862UniSTSRGSC3.4
Celera662,749,687 - 62,750,226UniSTS
Cytogenetic Map6q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 74 4 8
Low 2 40 41 25 19 25 8 11 30 33 11 8
Below cutoff 1 3 16 16 16 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY033093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY262017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000050372   ⟹   ENSRNOP00000045624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl663,784,937 - 63,905,114 (-)Ensembl
Rnor_6.0 Ensembl666,965,377 - 67,084,234 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083277   ⟹   ENSRNOP00000069458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl663,783,489 - 63,906,289 (-)Ensembl
Rnor_6.0 Ensembl666,963,510 - 67,085,390 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103119   ⟹   ENSRNOP00000082322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl663,784,937 - 63,906,289 (-)Ensembl
RefSeq Acc Id: NM_001100541   ⟹   NP_001094011
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,506,983 - 69,632,437 (-)NCBI
mRatBN7.2663,780,105 - 63,905,567 (-)NCBI
Rnor_6.0666,963,510 - 67,085,390 (-)NCBI
Rnor_5.0676,535,375 - 76,660,962 (-)NCBI
Celera662,747,220 - 62,869,241 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001414916   ⟹   NP_001401845
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,506,983 - 69,632,437 (-)NCBI
mRatBN7.2663,780,105 - 63,905,567 (-)NCBI
RefSeq Acc Id: NM_001414917   ⟹   NP_001401846
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,506,983 - 69,632,437 (-)NCBI
mRatBN7.2663,780,105 - 63,905,567 (-)NCBI
RefSeq Acc Id: XM_006240070   ⟹   XP_006240132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,632,134 (-)NCBI
mRatBN7.2663,780,105 - 63,905,268 (-)NCBI
Rnor_6.0666,960,126 - 67,085,131 (-)NCBI
Rnor_5.0676,535,375 - 76,660,962 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111963   ⟹   XP_038967891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,631,639 (-)NCBI
mRatBN7.2663,780,105 - 63,904,586 (-)NCBI
RefSeq Acc Id: XM_039111964   ⟹   XP_038967892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,632,134 (-)NCBI
mRatBN7.2663,780,105 - 63,905,269 (-)NCBI
RefSeq Acc Id: XM_039111966   ⟹   XP_038967894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,630,681 (-)NCBI
mRatBN7.2663,780,105 - 63,903,807 (-)NCBI
RefSeq Acc Id: XM_039111967   ⟹   XP_038967895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,630,662 (-)NCBI
mRatBN7.2663,780,105 - 63,903,779 (-)NCBI
RefSeq Acc Id: XM_063261663   ⟹   XP_063117733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,631,639 (-)NCBI
RefSeq Acc Id: XM_063261664   ⟹   XP_063117734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,510,367 - 69,540,358 (-)NCBI
RefSeq Acc Id: XM_063261665   ⟹   XP_063117735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8669,513,551 - 69,632,416 (-)NCBI
RefSeq Acc Id: NP_001094011   ⟸   NM_001100541
- Peptide Label: isoform 2
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL),   A6HBF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240132   ⟸   XM_006240070
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL),   D4AAF8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069458   ⟸   ENSRNOT00000083277
RefSeq Acc Id: ENSRNOP00000045624   ⟸   ENSRNOT00000050372
RefSeq Acc Id: XP_038967892   ⟸   XM_039111964
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967891   ⟸   XM_039111963
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967894   ⟸   XM_039111966
- Peptide Label: isoform X6
- UniProtKB: A6HBF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967895   ⟸   XM_039111967
- Peptide Label: isoform X6
- UniProtKB: A6HBF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000082322   ⟸   ENSRNOT00000103119
RefSeq Acc Id: NP_001401845   ⟸   NM_001414916
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JVE8 (UniProtKB/TrEMBL),   A0A8I6G9C1 (UniProtKB/TrEMBL),   A6HBF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401846   ⟸   NM_001414917
- Peptide Label: isoform 3
- UniProtKB: A6HBF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117733   ⟸   XM_063261663
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063117734   ⟸   XM_063261664
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063117735   ⟸   XM_063261665
- Peptide Label: isoform X7
Protein Domains
K Homology   KH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80WA4-F1-model_v2 AlphaFold Q80WA4 1-474 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621345 AgrOrtholog
BioCyc Gene G2FUF-37657 BioCyc
Ensembl Genes ENSRNOG00000031440 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050372.5 UniProtKB/TrEMBL
  ENSRNOT00000083277 ENTREZGENE
  ENSRNOT00000083277.2 UniProtKB/TrEMBL
  ENSRNOT00000103119 ENTREZGENE
  ENSRNOT00000103119.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro KH-I_NOVA_rpt1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH-I_NOVA_rpt2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH-I_NOVA_rpt3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:298992 UniProtKB/TrEMBL
NCBI Gene Nova1 ENTREZGENE
PANTHER KH DOMAIN CONTAINING RNA BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10288:SF229 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nova1 PhenoGen
PROSITE KH_TYPE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031440 RatGTEx
SMART SM00322 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JVE8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G9C1 ENTREZGENE, UniProtKB/TrEMBL
  A6HBF5 ENTREZGENE, UniProtKB/TrEMBL
  A6HBF6 ENTREZGENE, UniProtKB/TrEMBL
  A6HBF7 ENTREZGENE, UniProtKB/TrEMBL
  A6HBF8_RAT UniProtKB/TrEMBL
  D4AAF8 ENTREZGENE, UniProtKB/TrEMBL
  NOVA1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-12 Nova1  NOVA alternative splicing regulator 1  Nova1  neuro-oncological ventral antigen 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Nova1  neuro-oncological ventral antigen 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Nova1  neuro-oncological ventral antigen 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript has three splice variant isoforms 708602