Olig1 (oligodendrocyte transcription factor 1)

Gene: Olig1 (oligodendrocyte transcription factor 1) Rattus norvegicus

Analyze

Symbol:

Olig1

Name:

oligodendrocyte transcription factor 1

RGD ID:

621129

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Predicted to be involved in neurogenesis; positive regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to act upstream of or within neuron fate commitment. Predicted to be active in nucleus. Orthologous to human OLIG1 (oligodendrocyte transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Olg-1 bHLH protein; Olg1; oligo1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	44,000,450 - 44,002,592 (+)	NCBI		GRCr8
mRatBN7.2	11	30,514,379 - 30,516,521 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	30,514,379 - 30,516,521 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	39,201,413 - 39,203,556 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	31,872,852 - 31,874,995 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	31,047,260 - 31,049,404 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	31,428,377 - 31,430,519 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	31,428,358 - 31,430,517 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	35,037,423 - 35,039,565 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	31,244,279 - 31,246,421 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	31,283,750 - 31,285,889 (+)	NCBI
Celera	11	30,181,398 - 30,183,540 (+)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis type 1 (ISO)

autosomal dominant intellectual developmental disorder 7 (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

genetic disease (ISO)

Parkinson's disease 20 (ISO)

ZTTK Syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(1->4)-beta-D-glucan (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

butanal (ISO)

capsaicin (EXP)

carbofuran (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

clobetasol (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

diuron (EXP)

flavonoids (EXP)

folic acid (ISO)

gentamycin (EXP)

inulin (ISO)

lead diacetate (ISO)

lead(0) (ISO)

manganese(II) chloride (EXP)

methylmercury chloride (ISO)

N-nitrosodiethylamine (EXP,ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenethyl caffeate (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

rotenone (EXP)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

Theaflavin 3,3'-digallate (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon development (IBA,IEA)

neuron fate commitment (IEA,ISO)

oligodendrocyte development (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IBA,IEA)

sensory organ development (IBA,IEA)

Cellular Component

nucleus (IBA,IEA)

Molecular Function

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

E-box binding (IBA,IEA)

protein binding (ISO)

protein dimerization activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.	Lu QR, etal., Cell 2002 Apr 5;109(1):75-86.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Expression of transcription factors during oligodendroglial development.	Wegner M Microsc Res Tech 2001 Mar 15;52(6):746-52.
7.	The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.	Zhou Q and Anderson DJ, Cell 2002 Apr 5;109(1):61-73.
8.	[Effect of Yishen Daluo Decoction on the expression of PLP, Olig1, and Olig2 in mice with experimental autoimmune encephalomyelitis].	Zhu WH, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 May;34(5):562-5.

Additional References at PubMed

PMID:8889548	PMID:10719888	PMID:17872503	PMID:21132377	PMID:23973956	PMID:25762682	PMID:30143582	PMID:31702031

Genomics

Comparative Map Data

Olig1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	44,000,450 - 44,002,592 (+)	NCBI		GRCr8
mRatBN7.2	11	30,514,379 - 30,516,521 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	30,514,379 - 30,516,521 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	39,201,413 - 39,203,556 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	31,872,852 - 31,874,995 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	31,047,260 - 31,049,404 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	31,428,377 - 31,430,519 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	31,428,358 - 31,430,517 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	35,037,423 - 35,039,565 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	31,244,279 - 31,246,421 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	31,283,750 - 31,285,889 (+)	NCBI
Celera	11	30,181,398 - 30,183,540 (+)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

OLIG1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	33,070,141 - 33,072,413 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	33,070,141 - 33,072,413 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	34,442,447 - 34,444,719 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	33,364,443 - 33,366,596 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	33,364,442 - 33,366,595	NCBI
Celera	21	19,628,035 - 19,630,313 (+)	NCBI		Celera
Cytogenetic Map	21	q22.11	NCBI
HuRef	21	19,853,692 - 19,855,474 (+)	NCBI		HuRef
CHM1_1	21	34,004,519 - 34,006,797 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	31,438,351 - 31,440,623 (+)	NCBI		T2T-CHM13v2.0

Olig1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	91,066,657 - 91,068,827 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	91,066,660 - 91,068,821 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	91,269,769 - 91,271,939 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	91,269,772 - 91,271,933 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	91,270,014 - 91,272,184 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	91,158,628 - 91,160,798 (+)	NCBI		MGSCv36	mm8
Celera	16	92,345,636 - 92,347,806 (+)	NCBI		Celera
Cytogenetic Map	16	C3.3	NCBI
cM Map	16	52.67	NCBI

Olig1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	32,471,516 - 32,479,079 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	32,471,501 - 32,480,358 (+)	NCBI	ChiLan1.0	ChiLan1.0

OLIG1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	29,182,603 - 29,184,920 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	24,042,532 - 24,044,851 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	19,432,165 - 19,434,481 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

OLIG1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	27,718,925 - 27,721,301 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	27,719,026 - 27,719,862 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	27,712,713 - 27,715,091 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	27,922,967 - 27,925,345 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	27,922,930 - 27,925,359 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	27,790,717 - 27,793,095 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	27,800,806 - 27,803,184 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	28,303,802 - 28,306,183 (+)	NCBI		UU_Cfam_GSD_1.0

Olig1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	28,256,598 - 28,258,891 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936500	9,210,303 - 9,211,097 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936500	9,208,932 - 9,211,182 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OLIG1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	196,644,059 - 196,646,403 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	196,644,065 - 196,646,406 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	206,712,479 - 206,714,811 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OLIG1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	59,107,916 - 59,110,601 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	59,109,287 - 59,110,102 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666071	1,646,727 - 1,649,437 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Olig1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	21,308,928 - 21,309,722 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	21,308,831 - 21,310,898 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Olig1
6 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	569
Count of miRNA genes:	266
Interacting mature miRNAs:	330
Transcripts:	ENSRNOT00000002827
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598842	Glom10	Glomerulus QTL 10	3.4		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	1	35331169	Rat
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
1641927	Alcrsp10	Alcohol response QTL 10			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	11	8436674	53436674	Rat
724517	Uae18	Urinary albumin excretion QTL 18	3.7		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	16472047	44285911	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
1300130	Rf20	Renal function QTL 20	4.44		kidney glomerulus integrity trait (VT:0010546)	kidney glomerulus diameter (CMO:0001166)	11	29528418	60324829	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat

Markers in Region

AW523365

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	30,516,321 - 30,516,454 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	31,430,320 - 31,430,452	NCBI	Rnor6.0
Rnor_5.0	11	35,039,366 - 35,039,498	UniSTS	Rnor5.0
RGSC_v3.4	11	31,246,222 - 31,246,354	UniSTS	RGSC3.4
Celera	11	30,183,341 - 30,183,473	UniSTS
RH 3.4 Map	11	180.8	UniSTS
Cytogenetic Map	11	q11	UniSTS

AI836478

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	30,516,326 - 30,516,429 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	31,430,325 - 31,430,427	NCBI	Rnor6.0
Rnor_5.0	11	35,039,371 - 35,039,473	UniSTS	Rnor5.0
RGSC_v3.4	11	31,246,227 - 31,246,329	UniSTS	RGSC3.4
Celera	11	30,183,346 - 30,183,448	UniSTS
Cytogenetic Map	11	q11	UniSTS

Olig1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	30,514,821 - 30,515,116 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	31,428,820 - 31,429,114	NCBI	Rnor6.0
Rnor_5.0	11	35,037,866 - 35,038,160	UniSTS	Rnor5.0
RGSC_v3.4	11	31,244,722 - 31,245,016	UniSTS	RGSC3.4
Celera	11	30,181,841 - 30,182,135	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH139467

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	30,516,274 - 30,516,454 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	31,430,273 - 31,430,452	NCBI	Rnor6.0
Rnor_5.0	11	35,039,319 - 35,039,498	UniSTS	Rnor5.0
RGSC_v3.4	11	31,246,175 - 31,246,354	UniSTS	RGSC3.4
Celera	11	30,183,294 - 30,183,473	UniSTS
Cytogenetic Map	11	q11	UniSTS

ECD24242

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	30,514,790 - 30,514,940 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	31,428,789 - 31,428,938	NCBI	Rnor6.0
Rnor_5.0	11	35,037,835 - 35,037,984	UniSTS	Rnor5.0
RGSC_v3.4	11	31,244,691 - 31,244,840	UniSTS	RGSC3.4
Celera	11	30,181,810 - 30,181,959	UniSTS
Cytogenetic Map	11	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium								52
Low	1	9		8				22		7
Below cutoff	1	2	1	5	1	7	9		10	23	8	7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC112633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AW523365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO398101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000002827 ⟹ ENSRNOP00000002827

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	30,514,379 - 30,516,521 (+)	Ensembl
Rnor_6.0 Ensembl	11	31,428,358 - 31,430,517 (+)	Ensembl

RefSeq Acc Id:

NM_021770 ⟹ NP_068538

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	44,000,450 - 44,002,592 (+)	NCBI
mRatBN7.2	11	30,514,379 - 30,516,521 (+)	NCBI
Rnor_6.0	11	31,428,377 - 31,430,519 (+)	NCBI
Rnor_5.0	11	35,037,423 - 35,039,565 (+)	NCBI
RGSC_v3.4	11	31,244,279 - 31,246,421 (+)	RGD
Celera	11	30,181,398 - 30,183,540 (+)	RGD

Sequence:

show sequence

GCGCAGGTCCGCGGGGAGGGCGATCTGCCGACCGGCCCACCCTCGGGCGTCAGTGAAGGGCGCC
CTCGGTCGCCCCCACAGCCCCCGCCCCAGATGTACTATGCGGTTTCCCAGGCGCGTGTGAACGC
GGCTCCCGCGACCATGTTGCGGCCACAGCGGCCCGGAGATGTGCAGCTCGGGGCTTCGTTGTAC
GAGCTGGTGGGTTACAGGCAGCCACCCATCTCGTCATCCTCCTCCACCTCCTCCTCCTCTACCG
CGTCCCTTCTCCCTAAACCTGCGCGTGAGAAGCCTGAAGCTCCGCTCGCTGAGCCTCGGGGACC
AGCGCCGGAGTCCGGGGGCGCCCGGGCCGACGCCAAAGAGGAGCAGCAGCAGCAGCAGCTGAGG
CGCAAGATCAACAGCCGCGAGCGGAAGCGCATGCAGGACCTGAACTTGGCCATGGACGCGCTGC
GCGAAGTTATCCTACCCTACTCCGCGGCGCACTGCCAGGGCGCGCCGGGCCGTAAGCTCTCCAA
GATCGCTACGCTGCTGCTCGCCCGCAACTACATCCTGCTGCTGGGCAGCTCTCTGCAGGAGCTG
CGCCGCGCGCTCGGCGACGGTGCGGGACCCGCCGCCCCGCGCCTGCTCCTTGCGGGCCTGCCCC
TGCTGGCCGCCGCGCCGGGCTCTGTGCTGCTGGCACCGGGCGCCGTGGGACCCCCCGAAACGCT
GCGCCCCACCAAGTACCTGTCTCTAGCGCTCGACGAGCCACCGTGCGGCCAGTTCGCTCTCCCC
GCTGGTGGCGCGGGTAGCCCCGGCCTCTGCTCCTGTGCGGTGTGCAAGTTCCCGCATCTGGTCC
CCGCCGGCCTGGGCTTGGCAGCGGTGCAGGCTCAGTTCTCCAAGTGAGGGCTGGCTGGTCCCGG
GGCGGGGCGCGACCTCAGCCAATCTTCCCGCGCCCTCGCGTCCTGGATCTAGGGAGAGCTGGCC
CCAGAAAGGAGGACATTTCCAGACTTCTCACCCAGACGACAGACTGTAGGGCGCCTTCTTCCCC
GCCCCCACTCCCTGGCAATTAAAGTGACCCAAGCGGGTGTTCCAAGGAGCGACGCAGTTGCCTG
GGATTCTAGATGAATCCCACCAGTTTAGAGCCAGAAGTCATTGCCTCCCCACCATAAGCTCACC
CAGTAGCGGAGGTGACACCTCCACCCGGTGGTCTGGTTTTGTACCCGCGAGCATCGCGGAGACC
GGGAGGATGGTAGCCGGCGATGCGGTACAATGGGGTTGGGGTTGCCCTGGGTGCAGCGAAAGGC
TGTCCCCGAGCTTGGTGCCCTGGCATCCGCCAGTTCCCTGGCCTAAGAGCTGCTCCCCAACAGT
GTCCACTCAGAGGGGCCTCTTTCCTTGTCTGGGGCCTGAGCGCATAGGCTCCCTTGCTCTCACC
AGCCAAGCCCATGCGGATCTAGGAGGTCTAGAAAGCCCAGGCCACGAGTACAAACATCAAGGGT
GTTGCCGATGGGCCGCTCCGAAAAGCCCAGAGTCCGGTGTCCCGCGAGTGCGCGTGGTGACAGC
GCCTCGGTCGTTGGGTTTCGGAGTGGAGAAGTTCCTCTGGCTGGCCTCACAGTTCTGTCTTTCA
GGCTCGCACACCCAGGTGTTTTGTTGCAATTTACACTCCTTAGTCTCTGCTTCCCCTAATGGTA
GCTTAACCAACATTTGAGCTTGCTTGAAAACAAAATTCCAACCACGTTCCACGCCATCGGTGTT
CTGGACTTACTAAAATAGATAGCAAGGCATGTCGTAGCGTAGGCTTGTGAAGCTCGGTAATTAA
CGTTCTCACTAAAGTAAGCGGGCGAGGATCCCAAACCGCCGGTGGGTGGACAAACCCAGCTCCC
CTGGCTGCAGGCAGGAAGACGCTGGTTGTTAACCACAGCAAGGCAGCTGAAGAACTCCTTGGAC
CAGTGCATGCGTCGATGCCGCGTCTGCGTCTTGGCTTGTGATTAGCGTTAGCAAATTACCCAAG
ATTATTGCATAATCTCCACCAGCTTGCTTTGATTTTTTTTTTTATGTTGGAAGTTTTGGGTTGT
TGACAGTAGCCGAATTTAACTGGCGTTTTATTTGACCTCTAACTCTGTCCCCCTGAACTGTACA
GAAACCACAAAATAAAACGTCAACAGTCGAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_068538	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM10713	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002827
	ENSRNOP00000002827.6
	ENSRNOP00055023737
	ENSRNOP00060030369
	ENSRNOP00065007928
GenBank Protein	Q9WUQ3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_068538 ⟸ NM_021770

- UniProtKB:

Q9WUQ3 (UniProtKB/Swiss-Prot), A6JLE8 (UniProtKB/TrEMBL), A0A0H2UHA2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYYAVSQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSSTSSSSTASLLPKPARE
KPEAPLAEPRGPAPESGGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAA
HCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGDGAGPAAPRLLLAGLPLLAAAPGSVL
LAPGAVGPPETLRPTKYLSLALDEPPCGQFALPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQ
AQFSK

hide sequence

RefSeq Acc Id:

ENSRNOP00000002827 ⟸ ENSRNOT00000002827

Protein Domains

bHLH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9WUQ3-F1-model_v2	AlphaFold	Q9WUQ3	1-261	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698052

Promoter ID:

EPDNEW_R8577

Type:

single initiation site

Name:

Olig1_1

Description:

oligodendrocyte transcription factor 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	31,428,364 - 31,428,424	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621129	AgrOrtholog
BioCyc Gene	G2FUF-21906	BioCyc
Ensembl Genes	ENSRNOG00000028648	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055017462	UniProtKB/Swiss-Prot
	ENSRNOG00060021302	UniProtKB/Swiss-Prot
	ENSRNOG00065006879	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000002827	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000002827.8	UniProtKB/Swiss-Prot
	ENSRNOT00055029547	UniProtKB/Swiss-Prot
	ENSRNOT00060036859	UniProtKB/Swiss-Prot
	ENSRNOT00065010711	UniProtKB/Swiss-Prot
Gene3D-CATH	4.10.280.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	bHLH_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Olig1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:60394	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	60394	ENTREZGENE
PANTHER	BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR19290:SF7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Olig1	PhenoGen
PROSITE	BHLH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000028648	RatGTEx
	ENSRNOG00055017462	RatGTEx
	ENSRNOG00060021302	RatGTEx
	ENSRNOG00065006879	RatGTEx
SMART	HLH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47459	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0H2UHA2	ENTREZGENE, UniProtKB/TrEMBL
	A6JLE8	ENTREZGENE, UniProtKB/TrEMBL
	OLIG1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Olig1	oligodendrocyte transcription factor 1			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Olig1	oligodendrocyte transcription factor 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a basic helix-loop-helix domain	633488
gene_expression	expressed in neural progenitor cells	633488

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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