Gene: Syngap1 (synaptic Ras GTPase activating protein 1) Rattus norvegicus
Symbol: Syngap1
Name: synaptic Ras GTPase activating protein 1
Description: ENCODES a protein that exhibits GTPase activator activity; protein kinase binding; INVOLVED IN negative regulation of Ras protein signal transduction; positive regulation of GTPase activity; regulation of synaptic plasticity; PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH Mental Retardation, Autosomal Dominant 5 (ortholog); FOUND IN postsynaptic density; synapse; dendritic shaft (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neuronal RasGAP; p135 SynGAP; ras GTPase-activating protein SynGAP; ras/Rap GTPase-activating protein SynGAP; synaptic Ras GTPase activating protein 1 homolog; synaptic Ras GTPase activating protein 1 homolog (rat); synaptic Ras GTPase-activating protein 1; synaptic Ras-GAP 1; Syngap
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0205,535,434 - 5,564,657+NCBI
Rat Cytogenetic Map20p12 NCBI
RGSC Genome Assembly v5.0207,594,614 - 7,623,865+NCBI
RGSC Genome Assembly v3.4205,178,523 - 5,208,449+NCBI
Rat Celera Assembly206,608,780 - 6,637,810+NCBI
Genome Assembly 3.1205,191,049 - 5,207,973+NCBI

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Molecular Pathway Annotations
References - curated
References - uncurated
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Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Syngap1
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RGD Object Information
RGD ID: 621090
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE