Gene: Psen2 (presenilin 2) Rattus norvegicus
Symbol: Psen2
Name: presenilin 2
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); INVOLVED IN response to hypoxia; beta-amyloid metabolic process (ortholog); brain morphogenesis (ortholog); PARTICIPATES IN altered Notch signaling pathway involving the macromolecules modifying the main players; Alzheimer disease pathway; Notch signaling pathway; ASSOCIATED WITH Alzheimer Disease (ortholog); Alzheimer Disease Type 4 (ortholog); Breast Neoplasms (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); cytosol (ortholog); INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: presenilin-2; PS-2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01398,513,600 - 98,539,347 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.013103,521,460 - 103,547,174 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41395,934,674 - 95,951,836 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11396,123,177 - 96,145,989 (-)NCBI
Celera1391,515,731 - 91,532,398 (-)NCBI
Cytogenetic Map13q26NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Psen2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621060
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE