Gene: Pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) Rattus norvegicus
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Symbol: Pik3ca
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity; insulin receptor substrate binding (ortholog); kinase activity (ortholog); INVOLVED IN phosphatidylinositol phosphorylation; positive regulation of smooth muscle cell proliferation; response to butyrate; PARTICIPATES IN adenosine signaling pathway; altered phosphatidylinositol 3-kinase signaling pathway; altered phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH autosomal recessive polycystic kidney disease; Polycystic Kidney, Autosomal Recessive; acantholytic squamous cell skin carcinoma (ortholog); FOUND IN phosphatidylinositol 3-kinase complex; lamellipodium (ortholog); phosphatidylinositol 3-kinase complex, class IA (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; all-trans-retinoic acid; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC116320; p110alpha; phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphoinositide-3-kinase catalytic alpha polypeptide; phosphoinositide-3-kinase, catalytic, alpha polypeptide; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; ptdIns-3-kinase subunit alpha; ptdIns-3-kinase subunit p110-alpha; serine/threonine protein kinase PIK3CA
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02118,831,350 - 118,861,456 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02138,491,967 - 138,521,934 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42118,640,277 - 118,672,440 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12118,603,330 - 118,613,969 (+)NCBI
Celera2110,329,861 - 110,360,075 (+)NCBI
Cytogenetic Map2q24NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model