Ptprm (protein tyrosine phosphatase, receptor type, M) - Rat Genome Database

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Gene: Ptprm (protein tyrosine phosphatase, receptor type, M) Rattus norvegicus
Analyze
Symbol: Ptprm
Name: protein tyrosine phosphatase, receptor type, M
RGD ID: 620776
Description: Predicted to enable cadherin binding activity; identical protein binding activity; and transmembrane receptor protein tyrosine phosphatase activity. Predicted to be involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; retina layer formation; and retinal ganglion cell axon guidance. Predicted to act upstream of or within vasodilation. Predicted to be located in several cellular components, including adherens junction; lamellipodium; and perinuclear region of cytoplasm. Predicted to be active in cell-cell junction and intracellular non-membrane-bounded organelle. Orthologous to human PTPRM (protein tyrosine phosphatase receptor type M); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: protein tyrosine phosphatase receptor-type M; protein tyrosine phosphatase, receptor-type, M; receptor-type tyrosine-protein phosphatase mu
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89114,086,380 - 114,791,000 (-)NCBIGRCr8
mRatBN7.29106,639,573 - 107,343,698 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9106,639,573 - 107,343,698 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9115,034,215 - 115,735,168 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09120,156,426 - 120,857,356 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09118,500,097 - 119,201,056 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09114,846,095 - 115,555,261 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9114,846,095 - 115,555,261 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09114,341,760 - 115,047,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49105,784,922 - 106,503,148 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19106,019,977 - 106,025,031 (-)NCBI
Celera9103,813,416 - 104,503,006 (-)NCBICelera
Cytogenetic Map9q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
cantharidin  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDT  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethylparaben  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
isotretinoin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenylmercury acetate  (ISO)
PhIP  (EXP)
pirinixic acid  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression. Sahni S, etal., Biochim Biophys Acta Gen Subj. 2020 Nov;1864(11):129682. doi: 10.1016/j.bbagen.2020.129682. Epub 2020 Jul 12.
9. RPTP delta and the novel protein tyrosine phosphatase RPTP psi are expressed in restricted regions of the developing central nervous system. Sommer L, etal., Dev Dyn 1997 Jan;208(1):48-61.
Additional References at PubMed
PMID:8393854   PMID:9531566   PMID:10809770   PMID:14623235   PMID:15080886   PMID:15491993   PMID:15706045   PMID:15978577   PMID:16380380   PMID:17276081   PMID:17965016   PMID:18566238  


Genomics

Comparative Map Data
Ptprm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89114,086,380 - 114,791,000 (-)NCBIGRCr8
mRatBN7.29106,639,573 - 107,343,698 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9106,639,573 - 107,343,698 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9115,034,215 - 115,735,168 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09120,156,426 - 120,857,356 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09118,500,097 - 119,201,056 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09114,846,095 - 115,555,261 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9114,846,095 - 115,555,261 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09114,341,760 - 115,047,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49105,784,922 - 106,503,148 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19106,019,977 - 106,025,031 (-)NCBI
Celera9103,813,416 - 104,503,006 (-)NCBICelera
Cytogenetic Map9q37NCBI
PTPRM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38187,567,316 - 8,406,856 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl187,566,782 - 8,406,861 (+)EnsemblGRCh38hg38GRCh38
GRCh37187,567,314 - 8,406,854 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36187,557,314 - 8,396,859 (+)NCBINCBI36Build 36hg18NCBI36
Build 34187,557,816 - 8,396,852NCBI
Celera187,451,391 - 8,291,215 (+)NCBICelera
Cytogenetic Map18p11.23NCBI
HuRef187,531,039 - 8,371,216 (+)NCBIHuRef
CHM1_1187,567,289 - 8,407,034 (+)NCBICHM1_1
T2T-CHM13v2.0187,730,572 - 8,570,006 (+)NCBIT2T-CHM13v2.0
Ptprm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,973,843 - 67,661,486 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1766,973,942 - 67,661,452 (-)EnsemblGRCm39 Ensembl
GRCm381766,666,848 - 67,354,491 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1766,666,947 - 67,354,457 (-)EnsemblGRCm38mm10GRCm38
MGSCv371767,016,188 - 67,703,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361766,572,488 - 67,259,332 (-)NCBIMGSCv36mm8
Celera1770,960,452 - 71,652,526 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1737.88NCBI
Ptprm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554023,244,222 - 3,756,925 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554023,243,447 - 3,756,457 (-)NCBIChiLan1.0ChiLan1.0
PTPRM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21730,046,539 - 30,873,100 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11815,739,131 - 16,565,623 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0185,879,556 - 6,706,824 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1188,205,978 - 9,030,683 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl188,206,677 - 9,030,286 (-)Ensemblpanpan1.1panPan2
PTPRM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1774,005,682 - 74,597,498 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl773,815,186 - 74,609,116 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha773,205,288 - 73,988,613 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0773,864,685 - 74,648,938 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl773,863,785 - 74,660,558 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1773,566,351 - 74,351,414 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0773,596,130 - 74,369,637 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0773,895,451 - 74,674,439 (+)NCBIUU_Cfam_GSD_1.0
Ptprm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494470,374,418 - 71,176,141 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936670890,310 - 1,692,041 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936670890,316 - 1,692,033 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl699,350,303 - 100,092,883 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1699,350,301 - 100,092,966 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2692,516,719 - 92,550,399 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11866,564,562 - 67,398,541 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1866,773,588 - 67,398,542 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605041,491,594 - 42,326,520 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477016,990,056 - 17,508,167 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477016,900,925 - 17,507,775 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptprm
4644 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:548
Count of miRNA genes:254
Interacting mature miRNAs:322
Transcripts:ENSRNOT00000056366
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat

Markers in Region
D9Rat71  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29107,078,745 - 107,078,837 (+)MAPPERmRatBN7.2
Rnor_6.09115,291,868 - 115,291,959NCBIRnor6.0
Rnor_5.09114,784,005 - 114,784,096UniSTSRnor5.0
RGSC_v3.49106,234,733 - 106,234,825RGDRGSC3.4
RGSC_v3.49106,234,734 - 106,234,825UniSTSRGSC3.4
RGSC_v3.19106,444,213 - 106,444,305RGD
Celera9104,238,125 - 104,238,216UniSTS
RH 2.0 Map91078.6RGD
SHRSP x BN Map977.2299RGD
FHH x ACI Map985.72RGD
Cytogenetic Map9q37UniSTS
D9Rat166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29107,094,693 - 107,094,916 (+)MAPPERmRatBN7.2
Rnor_6.09115,307,816 - 115,308,038NCBIRnor6.0
Rnor_5.09114,799,953 - 114,800,175UniSTSRnor5.0
RGSC_v3.49106,250,681 - 106,250,903RGDRGSC3.4
RGSC_v3.49106,250,682 - 106,250,904UniSTSRGSC3.4
RGSC_v3.19106,460,161 - 106,460,383RGD
Celera9104,254,044 - 104,254,266UniSTS
SHRSP x BN Map977.2299RGD
SHRSP x BN Map977.2299UniSTS
Cytogenetic Map9q37UniSTS
RH143821  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29106,849,488 - 106,850,733 (+)MAPPERmRatBN7.2
Rnor_6.09115,056,475 - 115,057,719NCBIRnor6.0
Rnor_5.09114,549,344 - 114,550,588UniSTSRnor5.0
RGSC_v3.49106,004,398 - 106,005,642UniSTSRGSC3.4
Celera9104,016,441 - 104,017,685UniSTS
RH 3.4 Map4924.41UniSTS
Cytogenetic Map9q37UniSTS
BG371570  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29106,639,761 - 106,639,857 (+)MAPPERmRatBN7.2
Rnor_6.09114,846,284 - 114,846,379NCBIRnor6.0
Rnor_5.09114,341,949 - 114,342,044UniSTSRnor5.0
RGSC_v3.49105,785,111 - 105,785,206UniSTSRGSC3.4
Celera9103,813,605 - 103,813,700UniSTS
Cytogenetic Map9q37UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 7 12 8 11 64 29 34 11 8
Low 3 50 41 7 41 10 6 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001168632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000056366   ⟹   ENSRNOP00000053204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9106,639,573 - 107,343,698 (-)Ensembl
Rnor_6.0 Ensembl9114,846,095 - 115,555,261 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091316   ⟹   ENSRNOP00000074746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9106,639,573 - 107,343,698 (-)Ensembl
Rnor_6.0 Ensembl9114,846,161 - 115,382,445 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106479   ⟹   ENSRNOP00000085971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9106,654,353 - 107,343,698 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107262   ⟹   ENSRNOP00000080359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl9106,639,573 - 107,343,698 (-)Ensembl
RefSeq Acc Id: NM_001168632   ⟹   NP_001162103
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,086,380 - 114,790,477 (-)NCBI
mRatBN7.29106,639,573 - 107,343,698 (-)NCBI
Rnor_6.09114,846,095 - 115,555,261 (-)NCBI
Rnor_5.09114,341,760 - 115,047,495 (-)NCBI
RGSC_v3.49105,784,922 - 106,503,148 (-)RGD
Celera9103,813,416 - 104,503,006 (-)RGD
Sequence:
RefSeq Acc Id: XM_039083119   ⟹   XP_038939047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,086,477 - 114,520,725 (-)NCBI
mRatBN7.29106,639,674 - 107,280,659 (-)NCBI
RefSeq Acc Id: XM_039083125   ⟹   XP_038939053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,086,477 - 114,520,725 (-)NCBI
mRatBN7.29106,639,674 - 107,280,651 (-)NCBI
RefSeq Acc Id: XM_063266818   ⟹   XP_063122888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,086,477 - 114,790,900 (-)NCBI
RefSeq Acc Id: XM_063266820   ⟹   XP_063122890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,086,477 - 114,791,000 (-)NCBI
RefSeq Acc Id: XM_063266821   ⟹   XP_063122891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,086,477 - 114,471,780 (-)NCBI
RefSeq Acc Id: XM_063266822   ⟹   XP_063122892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,138,739 - 114,520,725 (-)NCBI
RefSeq Acc Id: XM_063266823   ⟹   XP_063122893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,230,238 - 114,520,725 (-)NCBI
RefSeq Acc Id: XM_063266824   ⟹   XP_063122894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89114,230,405 - 114,520,725 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001162103   ⟸   NM_001168632
- Peptide Label: precursor
- UniProtKB: F1LPJ1 (UniProtKB/TrEMBL),   A0A0G2K8V0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000053204   ⟸   ENSRNOT00000056366
RefSeq Acc Id: ENSRNOP00000074746   ⟸   ENSRNOT00000091316
RefSeq Acc Id: XP_038939047   ⟸   XM_039083119
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038939053   ⟸   XM_039083125
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000085971   ⟸   ENSRNOT00000106479
RefSeq Acc Id: ENSRNOP00000080359   ⟸   ENSRNOT00000107262
RefSeq Acc Id: XP_063122890   ⟸   XM_063266820
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063122888   ⟸   XM_063266818
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063122891   ⟸   XM_063266821
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063122892   ⟸   XM_063266822
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063122893   ⟸   XM_063266823
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063122894   ⟸   XM_063266824
- Peptide Label: isoform X8
Protein Domains
Fibronectin type-III   Ig-like   MAM   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LPJ1-F1-model_v2 AlphaFold F1LPJ1 1-1486 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620776 AgrOrtholog
BioCyc Gene G2FUF-26404 BioCyc
Ensembl Genes ENSRNOG00000011700 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056366 ENTREZGENE
  ENSRNOT00000056366.5 UniProtKB/TrEMBL
  ENSRNOT00000091316.2 UniProtKB/TrEMBL
  ENSRNOT00000106479.1 UniProtKB/TrEMBL
  ENSRNOT00000107262.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro ConA-like_dom UniProtKB/TrEMBL
  Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  R-PTP-mu_cat_rpt1 UniProtKB/TrEMBL
  Tyr/Dual-specificity_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_rcpt/non-rcpt UniProtKB/TrEMBL
KEGG Report rno:29616 UniProtKB/TrEMBL
NCBI Gene 29616 ENTREZGENE
PANTHER PROTEIN TYROSINE PHOSPHATASE, RECEPTOR TYPE, M UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PF00047 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PhenoGen Ptprm PhenoGen
PRINTS MAMDOMAIN UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  MAM_1 UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011700 RatGTEx
SMART FN3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
  FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A0G2K8V0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPJ0_RAT UniProtKB/TrEMBL
  A0A8I6A1C0_RAT UniProtKB/TrEMBL
  A6KF60_RAT UniProtKB/TrEMBL
  F1LPJ1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ptprm  protein tyrosine phosphatase, receptor type, M    protein tyrosine phosphatase, receptor-type, M  Name updated 1299863 APPROVED
2002-08-07 Ptprm  protein tyrosine phosphatase, receptor-type, M      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA is expressed in embryonic day 13.5 neural tube 633862