Enables alkylglycerophosphoethanolamine phosphodiesterase activity. Involved in several processes, including negative regulation of potassium ion transport; phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of smooth muscle cell proliferation. Located in caveola. Part of heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; congestive heart failure; and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein] and CAT protein inhibits the reaction [Glucose results in increased expression of GNAQ protein]
GNAQ protein affects the reaction [Glucose results in increased secretion of INS1 protein] and GNAQ protein affects the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein]]
acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein] and acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]
[bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to GNAQ protein modified form] and bisphenol A inhibits the reaction [ESR1 protein binds to GNAQ protein]
[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to GNAQ protein modified form]
acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein] and CAT protein inhibits the reaction [Glucose results in increased expression of GNAQ protein]
GNAQ protein affects the reaction [Glucose results in increased secretion of INS1 protein] and GNAQ protein affects the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein]]
[tanshinone co-treated with Fulvestrant] inhibits the reaction [IGF2 protein mutant form results in increased expression of GNAQ protein] and Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of GNAQ protein]]
acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein] and CAT protein inhibits the reaction [Glucose results in increased expression of GNAQ protein]
GNAQ protein affects the reaction [Glucose results in increased secretion of INS1 protein] and GNAQ protein affects the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein]]
[GNAQ gene mutant form results in increased susceptibility to [trametinib co-treated with omipalisib]] which results in increased cleavage of CASP3 protein more ...
RTKI cpd inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]] and Uridine Triphosphate inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]
Fingolimod Hydrochloride inhibits the reaction [sphingosine 1-phosphate results in increased expression of GNAQ protein] and Phytochemicals analog inhibits the reaction [sphingosine 1-phosphate results in increased expression of GNAQ protein]
acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] and CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]
GNAQ protein affects the reaction [Thrombin results in increased expression of CHST11 mRNA] and GNAQ protein affects the reaction [Thrombin results in increased expression of CHSY1 mRNA]
[GNAQ gene mutant form results in increased susceptibility to [trametinib co-treated with omipalisib]] which results in increased cleavage of CASP3 protein more ...
Sex differences in corticotropin-releasing factor receptor signaling and trafficking: potential role in female vulnerability to stress-related psychopathology.
An immunocapture/scintillation proximity analysis of G alpha q/11 activation by native serotonin (5-HT)2A receptors in rat cortex: blockade by clozapine and mirtazapine.
Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways.
Norepinephrine exocytosis stimulated by alpha-latrotoxin requires both external and stored Ca2+ and is mediated by latrophilin, G proteins and phospholipase C.
Temporal dispersion of activation of phospholipase C-beta1 and -gamma isoforms by angiotensin II in vascular smooth muscle cells. Role of alphaq/11, alpha12, and beta gamma G protein subunits.
Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins.
