Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | renal cell carcinoma | | ISO | ELOC (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:23797736 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | renal cell carcinoma | | ISO | ELOC (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:23797736 | |
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# | Reference Title | Reference Citation |
1. | RNA polymerase II transcription factor SIII. I. Identification, purification, and properties. | Bradsher JN, etal., J Biol Chem 1993 Dec 5;268(34):25587-93. |
2. | Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII. | Garrett KP, etal., Proc Natl Acad Sci U S A 1994 Jun 7;91(12):5237-41. |
3. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
4. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
5. | Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. | Kamura T, etal., Science. 1999 Apr 23;284(5414):657-61. |
6. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
7. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
8. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
9. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
10. | GOA pipeline | RGD automated data pipeline |
11. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
12. | Regulation of oxygen homeostasis by hypoxia-inducible factor 1. | Semenza GL Physiology (Bethesda). 2009 Apr;24:97-106. |
PMID:8889548 | PMID:9341197 | PMID:10224134 | PMID:11384984 | PMID:12477932 | PMID:15489334 | PMID:16498413 | PMID:17110338 | PMID:19037258 |
Eloc (Rattus norvegicus - Norway rat) |
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ELOC (Homo sapiens - human) |
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Eloc (Mus musculus - house mouse) |
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Eloc (Chinchilla lanigera - long-tailed chinchilla) |
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ELOC (Pan paniscus - bonobo/pygmy chimpanzee) |
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ELOC (Canis lupus familiaris - dog) |
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Eloc (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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ELOC (Sus scrofa - pig) |
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ELOC (Chlorocebus sabaeus - green monkey) |
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Eloc (Heterocephalus glaber - naked mole-rat) |
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Variants in Eloc
34 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH135267 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 36 | 52 | 37 | 18 | 37 | 8 | 10 | 74 | 34 | 40 | 11 | 8 |
Low | 7 | 5 | 4 | 1 | 4 | 1 | 1 | 1 | |||||
Below cutoff |
RefSeq Transcripts | NM_001270561 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
NM_001270562 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NM_001270563 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NM_022593 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006237724 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039110711 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AI555412 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC060566 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473984 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CK355540 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FM093546 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FM101371 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FM110992 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ213660 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ214805 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000005 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
L29259 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000050236 ⟹ ENSRNOP00000067410 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000082813 ⟹ ENSRNOP00000071456 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000090313 ⟹ ENSRNOP00000069739 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_001270561 ⟹ NP_001257490 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | NM_001270562 ⟹ NP_001257491 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | NM_001270563 ⟹ NP_001257492 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | NM_022593 ⟹ NP_072115 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006237724 ⟹ XP_006237786 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039110711 ⟹ XP_038966639 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Protein RefSeqs | NP_001257490 | (Get FASTA) | NCBI Sequence Viewer |
NP_001257491 | (Get FASTA) | NCBI Sequence Viewer | |
NP_001257492 | (Get FASTA) | NCBI Sequence Viewer | |
NP_072115 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006237786 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038966639 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAA41109 | (Get FASTA) | NCBI Sequence Viewer |
AAH60566 | (Get FASTA) | NCBI Sequence Viewer | |
EDM11496 | (Get FASTA) | NCBI Sequence Viewer | |
EDM11498 | (Get FASTA) | NCBI Sequence Viewer | |
EDM11499 | (Get FASTA) | NCBI Sequence Viewer | |
EDM11501 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000067410.2 | ||
ENSRNOP00000067924.1 | |||
ENSRNOP00000069739 | |||
ENSRNOP00000069739.1 | |||
ENSRNOP00055015190 | |||
ENSRNOP00055023736 | |||
ENSRNOP00060002166 | |||
ENSRNOP00060030217 | |||
ENSRNOP00065013203 | |||
GenBank Protein | P83941 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_072115 ⟸ NM_022593 |
- UniProtKB: | P83941 (UniProtKB/Swiss-Prot), A6JFA3 (UniProtKB/TrEMBL), A0A096MIY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | NP_001257491 ⟸ NM_001270562 |
- UniProtKB: | P83941 (UniProtKB/Swiss-Prot), A6JFA3 (UniProtKB/TrEMBL), A0A096MIY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | NP_001257492 ⟸ NM_001270563 |
- UniProtKB: | P83941 (UniProtKB/Swiss-Prot), A6JFA3 (UniProtKB/TrEMBL), A0A096MIY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | NP_001257490 ⟸ NM_001270561 |
- UniProtKB: | P83941 (UniProtKB/Swiss-Prot), A6JFA3 (UniProtKB/TrEMBL), A0A096MIY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006237786 ⟸ XM_006237724 |
- Peptide Label: | isoform X1 |
- UniProtKB: | P83941 (UniProtKB/Swiss-Prot), A6JFA3 (UniProtKB/TrEMBL), A0A096MIY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000071456 ⟸ ENSRNOT00000082813 |
RefSeq Acc Id: | ENSRNOP00000069739 ⟸ ENSRNOT00000090313 |
RefSeq Acc Id: | ENSRNOP00000067410 ⟸ ENSRNOT00000050236 |
RefSeq Acc Id: | XP_038966639 ⟸ XM_039110711 |
- Peptide Label: | isoform X1 |
- UniProtKB: | P83941 (UniProtKB/Swiss-Prot), A6JFA3 (UniProtKB/TrEMBL), A0A096MIY6 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-P83941-F1-model_v2 | AlphaFold | P83941 | 1-112 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13693523 | ||||||||
Promoter ID: | EPDNEW_R4047 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Eloc_1 | ||||||||
Description: | elongin C | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R4048 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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RGD ID: | 13693524 | ||||||||
Promoter ID: | EPDNEW_R4048 | ||||||||
Type: | initiation region | ||||||||
Name: | Eloc_2 | ||||||||
Description: | elongin C | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R4047 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:620658 | AgrOrtholog |
BioCyc Gene | G2FUF-42312 | BioCyc |
Ensembl Genes | ENSRNOG00000031730 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSRNOG00000051063 | UniProtKB/TrEMBL | |
ENSRNOG00055011110 | UniProtKB/Swiss-Prot | |
ENSRNOG00055017460 | UniProtKB/Swiss-Prot | |
ENSRNOG00060002027 | UniProtKB/Swiss-Prot | |
ENSRNOG00060021216 | UniProtKB/Swiss-Prot | |
ENSRNOG00065010662 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000050236.5 | UniProtKB/TrEMBL |
ENSRNOT00000076534.2 | UniProtKB/TrEMBL | |
ENSRNOT00000090313 | ENTREZGENE | |
ENSRNOT00000090313.2 | UniProtKB/Swiss-Prot | |
ENSRNOT00055018831 | UniProtKB/Swiss-Prot | |
ENSRNOT00055029546 | UniProtKB/Swiss-Prot | |
ENSRNOT00060003184 | UniProtKB/Swiss-Prot | |
ENSRNOT00060036706 | UniProtKB/Swiss-Prot | |
ENSRNOT00065017256 | UniProtKB/Swiss-Prot | |
IMAGE_CLONE | IMAGE:6918038 | IMAGE-MGC_LOAD |
InterPro | ELC1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SKP1-like | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SKP1/BTB/POZ_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Skp1_comp_POZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:64525 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MGC_CLONE | MGC:72822 | IMAGE-MGC_LOAD |
NCBI Gene | 64525 | ENTREZGENE |
PANTHER | ELONGIN-C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR20648 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Skp1_POZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Eloc | PhenoGen |
RatGTEx | ENSRNOG00000031730 | RatGTEx |
ENSRNOG00000051063 | RatGTEx | |
ENSRNOG00055011110 | RatGTEx | |
ENSRNOG00055017460 | RatGTEx | |
ENSRNOG00060002027 | RatGTEx | |
ENSRNOG00060021216 | RatGTEx | |
ENSRNOG00065010662 | RatGTEx | |
SMART | Skp1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF54695 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A096MIY6 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8L2UP21_RAT | UniProtKB/TrEMBL | |
A6JFA3 | ENTREZGENE, UniProtKB/TrEMBL | |
ELOC_RAT | UniProtKB/Swiss-Prot, ENTREZGENE | |
UniProt Secondary | Q63182 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2016-11-09 | Eloc | elongin C | Tceb1 | transcription elongation factor B subunit 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2016-03-16 | Tceb1 | transcription elongation factor B subunit 1 | Tceb1 | transcription elongation factor B (SIII), polypeptide 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2004-12-14 | Tceb1 | transcription elongation factor B (SIII), polypeptide 1 | elongation factor SIII p15 subunit | Name updated | 1299863 | APPROVED | |
2002-08-07 | Tceb1 | elongation factor SIII p15 subunit | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_physical_interaction | combines with 110 kDa and 18 kDa subunit to form the transcription factor B (SIII) complex | 730012 |
gene_process | important for trancriptional regulation with RNA polymerase II | 730008 |
gene_protein | predicted protein has 112 aa residues and masses 12.4 kDa | 730008 |