Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CD52 mRNA | CTD | PMID:36331819 | 1,1-dichloroethene | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of CD52 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of CD52 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of CD52 mRNA | CTD | PMID:19693291 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of CD52 mRNA | CTD | PMID:32145629 | 17beta-estradiol 3-benzoate | increases methylation | EXP | | 6480464 | estradiol 3-benzoate results in increased methylation of CD52 promoter | CTD | PMID:27415467 | 2,2',4,4',5,5'-hexachlorobiphenyl | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CD52 mRNA | CTD | PMID:17337447 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Cd52 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CD52 mRNA | CTD | PMID:24680724 and PMID:26377647 | 4,4'-sulfonyldiphenol | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | bisphenol S results in increased expression of CD52 mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Fenretinide results in increased expression of CD52 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | ISO | CD52 (Homo sapiens) | 6480464 | Decitabine affects the expression of CD52 mRNA | CTD | PMID:23300844 | 5-fluorouracil | affects expression | ISO | CD52 (Homo sapiens) | 6480464 | Fluorouracil affects the expression of CD52 mRNA | CTD | PMID:16584549 | 5-fluorouracil | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD52 mRNA] | CTD | PMID:15016801 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CD52 mRNA | CTD | PMID:24780913 and PMID:25825206 | 7,12-dimethyltetraphene | decreases expression | EXP | | 6480464 | 9 more ... | CTD | PMID:19480007 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CD52 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases methylation | ISO | CD52 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of CD52 gene | CTD | PMID:27153756 | aldehydo-D-glucose | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA | CTD | PMID:37567420 | all-trans-retinoic acid | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [Tretinoin co-treated with arsenic trioxide] results in increased expression of CD52 mRNA | CTD | PMID:15894607 | all-trans-retinoic acid | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of CD52 mRNA and Tretinoin results in increased expression of CD52 protein | CTD | PMID:10673743 more ... | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CD52 mRNA | CTD | PMID:16483693 | antirheumatic drug | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of CD52 mRNA | CTD | PMID:24449571 | Aroclor 1254 | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of CD52 mRNA | CTD | PMID:23650126 | arsenous acid | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CD52 mRNA | CTD | PMID:15894607 | arsenous acid | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of CD52 mRNA | CTD | PMID:10673743 more ... | arsenous acid | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CD52 mRNA | CTD | PMID:19128835 | benzo[a]pyrene | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of CD52 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | CD52 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CD52 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CD52 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CD52 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | affects expression | ISO | Cd52 (Mus musculus) | 6480464 | Benzo(a)pyrene affects the expression of CD52 mRNA | CTD | PMID:22342234 | Benzo[k]fluoranthene | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in increased expression of CD52 mRNA | CTD | PMID:26377693 | beta-naphthoflavone | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD52 mRNA | CTD | PMID:18164116 | beta-naphthoflavone | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | beta-Naphthoflavone results in decreased expression of CD52 mRNA | CTD | PMID:32858204 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of CD52 mRNA | CTD | PMID:26496021 | bisphenol A | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of CD52 mRNA | CTD | PMID:35598803 | bisphenol A | decreases methylation | ISO | CD52 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of CD52 gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CD52 mRNA | CTD | PMID:32145629 | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of CD52 promoter | CTD | PMID:27415467 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CD52 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol F | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | bisphenol F results in increased expression of CD52 mRNA | CTD | PMID:30951980 | buta-1,3-diene | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of CD52 mRNA | CTD | PMID:29038090 | cadmium atom | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CD52 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CD52 mRNA | CTD | PMID:35301059 | carbon nanotube | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of CD52 mRNA | CTD | PMID:18500788 | chlordecone | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of CD52 mRNA | CTD | PMID:33711761 | chloroprene | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Chloroprene results in decreased expression of CD52 mRNA | CTD | PMID:23125180 | choline | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD52 mRNA | CTD | PMID:20938992 | ciguatoxin CTX1B | affects expression | ISO | Cd52 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of CD52 mRNA | CTD | PMID:18353800 | cisplatin | affects expression | ISO | CD52 (Homo sapiens) | 6480464 | Cisplatin affects the expression of CD52 mRNA | CTD | PMID:23300844 | copper atom | multiple interactions | EXP | | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of CD52 mRNA | CTD | PMID:26033743 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CD52 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of CD52 mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | EXP | | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of CD52 mRNA | CTD | PMID:26033743 | cyclosporin A | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of CD52 mRNA | CTD | PMID:33631201 | cypermethrin | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | cypermethrin results in decreased expression of CD52 mRNA | CTD | PMID:35031408 | D-glucose | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA | CTD | PMID:37567420 | D-penicillamine | decreases expression | EXP | | 6480464 | Penicillamine results in decreased expression of CD52 mRNA | CTD | PMID:19575532 | dexamethasone | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of CD52 mRNA | CTD | PMID:21041162 | dextran sulfate | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Dextran Sulfate results in increased expression of CD52 mRNA | CTD | PMID:23894361 | diarsenic trioxide | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of CD52 mRNA | CTD | PMID:10673743 more ... | diarsenic trioxide | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CD52 mRNA | CTD | PMID:15894607 | diarsenic trioxide | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CD52 mRNA | CTD | PMID:19128835 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of CD52 mRNA | CTD | PMID:21658437 | diethylstilbestrol | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Diethylstilbestrol results in increased expression of CD52 mRNA | CTD | PMID:21041162 | dimethylarsinic acid | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of CD52 mRNA | CTD | PMID:34876320 | diquat | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Diquat results in decreased expression of CD52 mRNA | CTD | PMID:36851058 | disodium selenite | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of CD52 mRNA | CTD | PMID:18175754 | diuron | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | Diuron results in decreased expression of CD52 mRNA | CTD | PMID:35967413 | dorsomorphin | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | entinostat | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | entinostat results in increased expression of CD52 mRNA | CTD | PMID:27188386 | folic acid | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD52 mRNA | CTD | PMID:20938992 | fructose | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA | CTD | PMID:37567420 | glucose | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA | CTD | PMID:37567420 | glyphosate | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA | CTD | PMID:37567420 | hexachlorobenzene | increases expression | EXP | | 6480464 | Hexachlorobenzene results in increased expression of CD52 mRNA | CTD | PMID:15159207 | hydrogen peroxide | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of CD52 mRNA | CTD | PMID:15761015 | isotretinoin | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Isotretinoin results in increased expression of CD52 mRNA | CTD | PMID:20436886 | L-methionine | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD52 mRNA | CTD | PMID:20938992 | lipopolysaccharide | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of CD52 mRNA | CTD | PMID:27339419 | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of CD52 mRNA | CTD | PMID:31324951 | methylarsonic acid | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of CD52 mRNA | CTD | PMID:34876320 | methylmercury chloride | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of CD52 mRNA | CTD | PMID:28001369 | N-(6-acetamidohexyl)acetamide | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | hexamethylene bisacetamide results in decreased expression of CD52 mRNA | CTD | PMID:26941288 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD52 mRNA | CTD | PMID:18164116 | nickel atom | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Nickel results in increased expression of CD52 mRNA | CTD | PMID:24768652 and PMID:25583101 | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of CD52 mRNA | CTD | PMID:33484710 | ozone | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Ozone results in decreased expression of CD52 mRNA | CTD | PMID:17095637 | ozone | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of CD52 mRNA | CTD | PMID:35430440 | ozone | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CD52 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of CD52 mRNA | CTD | PMID:34911549 | panobinostat | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | panobinostat results in increased expression of CD52 mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD52 mRNA | CTD | PMID:27188386 | paracetamol | affects expression | ISO | Cd52 (Mus musculus) | 6480464 | Acetaminophen affects the expression of CD52 mRNA | CTD | PMID:17562736 | pentanal | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | pentanal results in increased expression of CD52 mRNA | CTD | PMID:26079696 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CD52 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | decreases expression | ISO | CD52 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of CD52 mRNA | CTD | PMID:36326898 | perfluorooctanoic acid | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of CD52 mRNA | CTD | PMID:37738295 | phenobarbital | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of CD52 mRNA | CTD | PMID:19270015 | pirinixic acid | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of CD52 mRNA | CTD | PMID:17426115 | progesterone | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of CD52 mRNA | CTD | PMID:19693291 | propanal | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of CD52 mRNA | CTD | PMID:26079696 | raloxifene | affects expression | EXP | | 6480464 | Raloxifene Hydrochloride affects the expression of CD52 mRNA | CTD | PMID:16079270 | SB 431542 | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of CD52 mRNA | CTD | PMID:23806026 | silicon dioxide | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of CD52 mRNA | CTD | PMID:23221170 and PMID:29341224 | sodium arsenate | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of CD52 mRNA | CTD | PMID:34876320 | sodium arsenite | multiple interactions | ISO | Cd52 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of CD52 mRNA | CTD | PMID:34876320 | tamoxifen | affects expression | ISO | Cd52 (Mus musculus) | 6480464 | Tamoxifen affects the expression of CD52 mRNA | CTD | PMID:20937368 | testosterone | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Testosterone results in decreased expression of CD52 mRNA | CTD | PMID:19693291 | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of CD52 mRNA | CTD | PMID:26496021 | tetrachloromethane | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of CD52 mRNA | CTD | PMID:27339419 | tetrachloromethane | affects expression | ISO | Cd52 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of CD52 mRNA | CTD | PMID:31919559 | titanium dioxide | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CD52 mRNA | CTD | PMID:23557971 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of CD52 mRNA | CTD | PMID:25729387 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CD52 mRNA | CTD | PMID:33387578 | valproic acid | increases methylation | ISO | CD52 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of CD52 gene | CTD | PMID:29154799 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of CD52 mRNA | CTD | PMID:35594946 | valproic acid | increases expression | ISO | CD52 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CD52 mRNA | CTD | PMID:28001369 | vancomycin | decreases expression | ISO | Cd52 (Mus musculus) | 6480464 | Vancomycin results in decreased expression of CD52 mRNA | CTD | PMID:18930951 | vorinostat | multiple interactions | ISO | CD52 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD52 mRNA | CTD | PMID:27188386 | vorinostat | increases expression | ISO | Cd52 (Mus musculus) | 6480464 | vorinostat results in increased expression of CD52 mRNA | CTD | PMID:26941288 | |