Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of CDK16 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | affects expression | ISO | Cdk16 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of CDK16 mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of CDK16 mRNA | CTD | PMID:21983209 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CDK16 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CDK16 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CDK16 mRNA | CTD | PMID:21215274 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of CDK16 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of CDK16 mRNA | CTD | PMID:21346803 | 2-nitrofluorene | increases expression | EXP | | 6480464 | 2-nitrofluorene results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Cdk16 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CDK16 mRNA | CTD | PMID:20188158 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of CDK16 mRNA | CTD | PMID:18648102 | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CDK16 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | all-trans-retinoic acid | increases expression | ISO | CDK16 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of CDK16 mRNA | CTD | PMID:16054129 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CDK16 mRNA | CTD | PMID:16483693 | benzo[a]pyrene diol epoxide I | increases expression | ISO | CDK16 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CDK16 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | CDK16 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CDK16 protein | CTD | PMID:33376534 | cadmium atom | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDK16 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of CDK16 promoter | CTD | PMID:22457795 | cadmium dichloride | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDK16 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | ISO | CDK16 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of CDK16 protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CDK16 gene] | CTD | PMID:28238834 | coumarin | increases phosphorylation | ISO | CDK16 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of CDK16 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | CDK16 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CDK16 mRNA | CTD | PMID:25562108 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | dimethylarsinous acid | increases expression | ISO | CDK16 (Homo sapiens) | 6480464 | dimethylarsinous acid results in increased expression of CDK16 mRNA | CTD | PMID:23487506 | dorsomorphin | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CDK16 mRNA | CTD | PMID:27188386 | Erionite | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | erionite results in decreased expression of CDK16 mRNA | CTD | PMID:29279043 | ethanol | affects splicing | ISO | Cdk16 (Mus musculus) | 6480464 | Ethanol affects the splicing of CDK16 mRNA | CTD | PMID:30319688 | FR900359 | decreases phosphorylation | ISO | CDK16 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of CDK16 protein | CTD | PMID:37730182 | genistein | multiple interactions | EXP | | 6480464 | [Genistein co-treated with Methoxychlor] results in decreased expression of CDK16 mRNA | CTD | PMID:21782745 | hydrogen cyanide | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | Hydrogen Cyanide results in decreased expression of CDK16 mRNA | CTD | PMID:33914522 | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | CDK16 (Homo sapiens) | 6480464 | Arbutin results in decreased expression of CDK16 mRNA | CTD | PMID:17103032 | LY294002 | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CDK16 mRNA] | CTD | PMID:12710931 | methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | methidathion | increases expression | ISO | Cdk16 (Mus musculus) | 6480464 | methidathion results in increased expression of CDK16 mRNA | CTD | PMID:34813904 | methoxychlor | multiple interactions | EXP | | 6480464 | [Genistein co-treated with Methoxychlor] results in decreased expression of CDK16 mRNA | CTD | PMID:21782745 | methoxychlor | increases methylation | EXP | | 6480464 | Methoxychlor results in increased methylation of CDK16 gene | CTD | PMID:23303685 | methylseleninic acid | decreases expression | ISO | CDK16 (Homo sapiens) | 6480464 | methylselenic acid results in decreased expression of CDK16 mRNA | CTD | PMID:12517777 | N-methyl-4-phenylpyridinium | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CDK16 mRNA] | CTD | PMID:12710931 | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | ozone | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of CDK16 mRNA | CTD | PMID:35430440 | paclitaxel | increases expression | EXP | | 6480464 | Paclitaxel analog results in increased expression of CDK16 mRNA and Paclitaxel results in increased expression of CDK16 mRNA | CTD | PMID:15585946 | pentachlorophenol | increases expression | ISO | Cdk16 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of CDK16 mRNA | CTD | PMID:23892564 | piperonyl butoxide | increases expression | EXP | | 6480464 | Piperonyl Butoxide results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | pirinixic acid | increases expression | ISO | Cdk16 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of CDK16 mRNA | CTD | PMID:18301758 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of CDK16 mRNA | CTD | PMID:15890375 | potassium cyanide | increases expression | ISO | Cdk16 (Mus musculus) | 6480464 | Potassium Cyanide results in increased expression of CDK16 mRNA | CTD | PMID:33914522 | SB 431542 | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CDK16 mRNA | CTD | PMID:27188386 | sodium arsenate | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of CDK16 mRNA | CTD | PMID:21795629 | sodium arsenite | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of CDK16 mRNA | CTD | PMID:25270620 | thimerosal | decreases expression | ISO | CDK16 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of CDK16 mRNA | CTD | PMID:27188386 | triptonide | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | triptonide results in decreased expression of CDK16 mRNA | CTD | PMID:33045310 | trovafloxacin | multiple interactions | ISO | Cdk16 (Mus musculus) | 6480464 | [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in decreased expression of CDK16 mRNA | CTD | PMID:18930950 | valproic acid | increases expression | ISO | Cdk16 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of CDK16 mRNA | CTD | PMID:21427059 | valproic acid | multiple interactions | ISO | CDK16 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CDK16 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | CDK16 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CDK16 mRNA | CTD | PMID:23179753 more ... | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of CDK16 mRNA | CTD | PMID:23665938 | valproic acid | decreases expression | ISO | Cdk16 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of CDK16 mRNA | CTD | PMID:21427059 | vanadium atom | decreases expression | ISO | CDK16 (Homo sapiens) | 6480464 | Vanadium results in decreased expression of CDK16 mRNA | CTD | PMID:19000753 | vanadium(0) | decreases expression | ISO | CDK16 (Homo sapiens) | 6480464 | Vanadium results in decreased expression of CDK16 mRNA | CTD | PMID:19000753 | |