Aimp1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1) - Rat Genome Database

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Gene: Aimp1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1) Rattus norvegicus
Analyze
Symbol: Aimp1
Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
RGD ID: 620466
Description: Predicted to enable several functions, including GTPase binding activity; cytokine activity; and protein homodimerization activity. Involved in blood vessel morphogenesis and defense response to virus. Predicted to be located in cell surface; cytosol; and extracellular space. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Biomarker of myocardial infarction and neurodegenerative disease. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 3. Orthologous to human AIMP1 (aminoacyl tRNA synthetase complex interacting multifunctional protein 1); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: aminoacyl tRNA synthase complex-interacting multifunctional protein 1; Emap2; endothelial monocyte activating polypeptide 2; MGC112632; Scye1; small inducible cytokine subfamily E, member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Aimp1-ps3  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82223,825,930 - 223,849,477 (-)NCBIGRCr8
mRatBN7.22221,151,907 - 221,175,458 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2221,151,904 - 221,175,728 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2228,811,082 - 228,834,491 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02226,710,760 - 226,734,165 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02221,568,416 - 221,591,821 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02237,727,782 - 237,751,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2237,727,764 - 237,751,378 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02256,268,301 - 256,291,846 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42230,142,679 - 230,166,226 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12230,137,339 - 230,140,141 (-)NCBI
Celera2213,387,972 - 213,411,498 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
asperentin  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Brevianamide A  (ISO)
Brodifacoum  (EXP)
cannabidiol  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
mifepristone  (ISO)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N-acetyl-L-cysteine  (ISO)
nefazodone  (EXP)
neoechinulin A  (ISO)
nickel dichloride  (ISO)
nitric oxide  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
parathion  (ISO)
phenethyl caffeate  (ISO)
piroxicam  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sterigmatocystin  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
TMC-120A  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Expression of EMAP-II by activated monocytes/microglial cells in different regions of the rat hippocampus after trimethyltin-induced brain damage. Brabeck C, etal., Exp Neurol 2002 Sep;177(1):341-6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Accumulation of the proinflammatory cytokine endothelial-monocyte-activating polypeptide II in ramified microglial cells in brains of Borna virus infected Lewis rats. Mueller CA, etal., Neurosci Lett. 2003 Mar 27;339(3):215-8.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Potential role for antiangiogenic proteins in the myocardial infarction repair process. Thompson JL, etal., J Surg Res. 2004 Jan;116(1):156-64.
Additional References at PubMed
PMID:10791971   PMID:11306575   PMID:11741979   PMID:12060739   PMID:12477932   PMID:14500886   PMID:17001013   PMID:17393072   PMID:18705801   PMID:19131329   PMID:19289464   PMID:19946888  
PMID:20083091   PMID:21969114   PMID:22214516   PMID:22531886   PMID:24337748   PMID:25600803   PMID:30361391   PMID:35352799  


Genomics

Comparative Map Data
Aimp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82223,825,930 - 223,849,477 (-)NCBIGRCr8
mRatBN7.22221,151,907 - 221,175,458 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2221,151,904 - 221,175,728 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2228,811,082 - 228,834,491 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02226,710,760 - 226,734,165 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02221,568,416 - 221,591,821 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02237,727,782 - 237,751,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2237,727,764 - 237,751,378 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02256,268,301 - 256,291,846 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42230,142,679 - 230,166,226 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12230,137,339 - 230,140,141 (-)NCBI
Celera2213,387,972 - 213,411,498 (-)NCBICelera
Cytogenetic Map2q43NCBI
AIMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384106,315,544 - 106,349,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4106,315,544 - 106,349,456 (+)EnsemblGRCh38hg38GRCh38
GRCh374107,236,701 - 107,270,613 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364107,457,124 - 107,489,021 (+)NCBINCBI36Build 36hg18NCBI36
Build 344107,595,278 - 107,627,176NCBI
Celera4104,536,003 - 104,569,617 (+)NCBICelera
Cytogenetic Map4q24NCBI
HuRef4102,971,448 - 103,005,063 (+)NCBIHuRef
CHM1_14107,213,718 - 107,247,313 (+)NCBICHM1_1
T2T-CHM13v2.04109,626,616 - 109,660,528 (+)NCBIT2T-CHM13v2.0
Aimp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393132,366,259 - 132,390,151 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3132,366,242 - 132,390,131 (-)EnsemblGRCm39 Ensembl
GRCm383132,660,498 - 132,684,390 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3132,660,481 - 132,684,370 (-)EnsemblGRCm38mm10GRCm38
MGSCv373132,323,462 - 132,346,843 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363132,597,809 - 132,621,136 (-)NCBIMGSCv36mm8
Celera3139,089,155 - 139,112,528 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map361.48NCBI
Aimp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554963,072,341 - 3,108,672 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554963,073,480 - 3,108,012 (-)NCBIChiLan1.0ChiLan1.0
AIMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23104,413,891 - 104,446,165 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14104,709,130 - 104,742,902 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0498,796,320 - 98,830,095 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14109,403,236 - 109,436,566 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4109,404,352 - 109,436,566 (+)Ensemblpanpan1.1panPan2
AIMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13227,062,812 - 27,102,654 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3227,062,950 - 27,101,977 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3214,924,177 - 14,964,013 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03227,294,550 - 27,334,400 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3227,294,673 - 27,334,401 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13227,288,505 - 27,328,329 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03227,034,148 - 27,073,927 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03212,786,600 - 12,826,428 (-)NCBIUU_Cfam_GSD_1.0
Aimp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530114,082,808 - 14,119,926 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936814798,948 - 837,334 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936814800,085 - 837,140 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AIMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8115,432,088 - 115,476,704 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18115,437,453 - 115,476,735 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28123,840,344 - 123,893,742 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AIMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1754,308,865 - 54,340,947 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603732,942,446 - 32,974,714 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aimp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248302,624,310 - 2,649,099 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248302,624,071 - 2,649,265 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aimp1
263 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:16
Transcripts:ENSRNOT00000015213
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
1359019Hrtrt19Heart rate QTL 192.9heart pumping trait (VT:2000009)heart rate (CMO:0000002)2219753301226277316Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat

Markers in Region
D2Rat138  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22221,166,836 - 221,167,075 (+)MAPPERmRatBN7.2
Rnor_6.02237,742,710 - 237,742,948NCBIRnor6.0
Rnor_5.02256,283,229 - 256,283,467UniSTSRnor5.0
RGSC_v3.42230,157,607 - 230,157,845UniSTSRGSC3.4
RGSC_v3.42230,157,606 - 230,157,845RGDRGSC3.4
RGSC_v3.12230,144,347 - 230,144,585RGD
Celera2213,402,898 - 213,403,136UniSTS
RH 3.4 Map21551.3RGD
RH 3.4 Map21551.3UniSTS
RH 2.0 Map21111.7RGD
SHRSP x BN Map293.1498RGD
FHH x ACI Map2106.2698RGD
Cytogenetic Map2q43UniSTS
RH128194  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22219,862,686 - 219,862,886 (+)MAPPERmRatBN7.2
Rnor_6.02236,427,410 - 236,427,609NCBIRnor6.0
Rnor_5.02254,976,344 - 254,976,543UniSTSRnor5.0
RGSC_v3.42228,784,465 - 228,784,664UniSTSRGSC3.4
RGSC_v3.4X114,406,191 - 114,406,389UniSTSRGSC3.4
Celera2212,118,709 - 212,118,908UniSTS
CeleraX91,534,121 - 91,534,319UniSTS
Cytogenetic MapXq33UniSTS
Cytogenetic Map2q43UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000015213   ⟹   ENSRNOP00000015213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2221,151,904 - 221,175,504 (-)Ensembl
Rnor_6.0 Ensembl2237,727,764 - 237,751,378 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111833   ⟹   ENSRNOP00000085380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2221,151,904 - 221,175,728 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112244   ⟹   ENSRNOP00000077517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2221,151,904 - 221,168,748 (-)Ensembl
RefSeq Acc Id: NM_053757   ⟹   NP_446209
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82223,825,930 - 223,849,477 (-)NCBI
mRatBN7.22221,151,907 - 221,175,458 (-)NCBI
Rnor_6.02237,727,782 - 237,751,327 (-)NCBI
Rnor_5.02256,268,301 - 256,291,846 (-)NCBI
RGSC_v3.42230,142,679 - 230,166,226 (-)RGD
Celera2213,387,972 - 213,411,498 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446209 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG41431 (Get FASTA)   NCBI Sequence Viewer  
  AAH98675 (Get FASTA)   NCBI Sequence Viewer  
  EDL82221 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000015213
  ENSRNOP00000015213.4
  ENSRNOP00000077517.1
  ENSRNOP00000085380.1
Reference Protein Sequences
RefSeq Acc Id: NP_446209   ⟸   NM_053757
- UniProtKB: Q4G079 (UniProtKB/TrEMBL),   A6HVT5 (UniProtKB/TrEMBL),   A0A8I6A263 (UniProtKB/TrEMBL),   A0A8I5Y7U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000015213   ⟸   ENSRNOT00000015213
RefSeq Acc Id: ENSRNOP00000085380   ⟸   ENSRNOT00000111833
RefSeq Acc Id: ENSRNOP00000077517   ⟸   ENSRNOT00000112244
Protein Domains
tRNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4G079-F1-model_v2 AlphaFold Q4G079 1-315 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691763
Promoter ID:EPDNEW_R2288
Type:multiple initiation site
Name:Aimp1_1
Description:aminoacyl tRNA synthetase complex-interacting multifunctionalprotein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02237,751,324 - 237,751,384EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620466 AgrOrtholog
BioCyc Gene G2FUF-51176 BioCyc
Ensembl Genes ENSRNOG00000011384 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015213 ENTREZGENE
  ENSRNOT00000015213.7 UniProtKB/TrEMBL
  ENSRNOT00000111833.1 UniProtKB/TrEMBL
  ENSRNOT00000112244.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7322792 IMAGE-MGC_LOAD
InterPro NA-bd_OB-fold UniProtKB/TrEMBL
  tRNA-bd_dom UniProtKB/TrEMBL
KEGG Report rno:114632 UniProtKB/TrEMBL
MGC_CLONE MGC:112632 IMAGE-MGC_LOAD
NCBI Gene 114632 ENTREZGENE
PANTHER AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 UniProtKB/TrEMBL
  TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER UniProtKB/TrEMBL
Pfam tRNA_bind UniProtKB/TrEMBL
PhenoGen Aimp1 PhenoGen
PROSITE TRBD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011384 RatGTEx
Superfamily-SCOP Nucleic_acid_OB UniProtKB/TrEMBL
UniProt A0A8I5Y7U7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A263 ENTREZGENE, UniProtKB/TrEMBL
  A6HVT5 ENTREZGENE
  Q4G079 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6HVT5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-12-15 Aimp1  aminoacyl tRNA synthetase complex-interacting multifunctional protein 1  Scye1  small inducible cytokine subfamily E, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Scye1  small inducible cytokine subfamily E, member 1    endothelial monocyte activating polypeptide 2  Name updated 1299863 APPROVED
2002-08-07 Scye1  endothelial monocyte activating polypeptide 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression is upregulated in microglial cells by neurotoxicant trimethyltin 724676