Ajuba (ajuba LIM protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ajuba (ajuba LIM protein) Rattus norvegicus
Analyze
Symbol: Ajuba
Name: ajuba LIM protein
RGD ID: 620407
Description: Predicted to enable several functions, including actin filament binding activity; alpha-catenin binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including regulation of cellular response to hypoxia; regulation of gene expression; and regulation of intracellular signal transduction. Predicted to act upstream of or within several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; focal adhesion assembly; and regulation of cellular biosynthetic process. Located in cell-cell junction. Orthologous to human AJUBA (ajuba LIM protein); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ajuba homolog; ajuba homolog (Xenopus laevis); Jub; jub, ajuba homolog; jub, ajuba homolog (Xenopus laevis); LIM domain-containing protein ajuba; MGC93830
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,989,796 - 32,000,042 (-)NCBIGRCr8
mRatBN7.21528,019,775 - 28,031,537 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,019,778 - 28,030,021 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,858,600 - 29,868,825 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,005,812 - 31,016,041 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,255,934 - 29,266,128 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,208,210 - 33,218,456 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,208,216 - 33,218,456 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,092,299 - 37,103,304 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,627,633 - 32,637,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,644,597 - 32,652,711 (-)NCBI
Celera1527,595,895 - 27,610,669 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,4-dichloroaniline  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dibutyl phthalate  (EXP,ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
glycidyl methacrylate  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mifepristone  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
Monobutylphthalate  (EXP)
N-nitrosodiethylamine  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phencyclidine  (ISO)
phenobarbital  (ISO)
pioglitazone  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium dichromate  (EXP)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin. Marie H, etal., J Biol Chem. 2003 Jan 10;278(2):1220-8. Epub 2002 Nov 1.
3. The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba. Marie H, etal., Mol Cell Neurosci 2002 Feb;19(2):152-64.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10330178   PMID:12477932   PMID:15728191   PMID:15870270   PMID:15870274   PMID:17909014   PMID:18331720   PMID:18347060   PMID:18805794   PMID:19376971   PMID:20303269   PMID:20616046  
PMID:22286099  


Genomics

Comparative Map Data
Ajuba
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,989,796 - 32,000,042 (-)NCBIGRCr8
mRatBN7.21528,019,775 - 28,031,537 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,019,778 - 28,030,021 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,858,600 - 29,868,825 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,005,812 - 31,016,041 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,255,934 - 29,266,128 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,208,210 - 33,218,456 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,208,216 - 33,218,456 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,092,299 - 37,103,304 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,627,633 - 32,637,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,644,597 - 32,652,711 (-)NCBI
Celera1527,595,895 - 27,610,669 (-)NCBICelera
Cytogenetic Map15p13NCBI
AJUBA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,971,177 - 22,982,551 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,971,177 - 22,982,551 (-)EnsemblGRCh38hg38GRCh38
GRCh371423,440,386 - 23,451,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,510,249 - 22,521,691 (-)NCBINCBI36Build 36hg18NCBI36
Build 341422,510,248 - 22,516,272NCBI
Celera143,303,299 - 3,314,741 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,557,642 - 3,569,085 (-)NCBIHuRef
CHM1_11423,439,040 - 23,450,482 (-)NCBICHM1_1
T2T-CHM13v2.01417,171,795 - 17,183,169 (-)NCBIT2T-CHM13v2.0
Ajuba
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,804,926 - 54,815,118 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,804,929 - 54,815,015 (-)EnsemblGRCm39 Ensembl
GRCm381454,567,469 - 54,577,661 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,567,472 - 54,577,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,186,309 - 55,196,253 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,521,677 - 53,531,621 (-)NCBIMGSCv36mm8
Celera1452,356,267 - 52,366,350 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.84NCBI
Ajuba
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,318,597 - 37,329,155 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,318,597 - 37,329,068 (+)NCBIChiLan1.0ChiLan1.0
AJUBA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,403,945 - 24,415,391 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,613,714 - 23,631,909 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,791,309 - 3,802,763 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,889,443 - 21,900,700 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,889,443 - 21,900,700 (-)Ensemblpanpan1.1panPan2
AJUBA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,272,408 - 3,302,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,272,405 - 3,301,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,219,989 - 3,250,272 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,379,492 - 3,410,108 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,380,278 - 3,410,168 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,070,717 - 3,101,039 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,132,252 - 3,162,764 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,394,515 - 3,424,826 (-)NCBIUU_Cfam_GSD_1.0
Ajuba
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,047,132 - 35,057,420 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,331,566 - 1,341,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,331,568 - 1,341,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AJUBA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,063,058 - 76,076,585 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1776,063,009 - 76,072,884 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AJUBA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,341,841 - 23,352,630 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,341,249 - 23,352,685 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605923,067,978 - 23,079,304 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ajuba
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,552,287 - 9,563,472 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,551,664 - 9,562,773 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ajuba
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:846
Count of miRNA genes:307
Interacting mature miRNAs:391
Transcripts:ENSRNOT00000017753
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

Markers in Region
D15Rat6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,030,665 - 28,030,847 (+)MAPPERmRatBN7.2
Rnor_6.01533,219,101 - 33,219,282NCBIRnor6.0
Rnor_5.01537,103,190 - 37,103,371UniSTSRnor5.0
RGSC_v3.41532,638,412 - 32,638,778RGDRGSC3.4
RGSC_v3.41532,638,506 - 32,638,707UniSTSRGSC3.4
RGSC_v3.11532,654,112 - 32,654,478RGD
RH 2.0 Map15174.3RGD
SHRSP x BN Map1525.6198RGD
Cytogenetic Map15p13UniSTS
D15Rat85  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,030,612 - 28,030,847 (+)MAPPERmRatBN7.2
Rnor_6.01533,219,048 - 33,219,282NCBIRnor6.0
Rnor_5.01537,103,137 - 37,103,371UniSTSRnor5.0
RGSC_v3.41532,638,452 - 32,638,707RGDRGSC3.4
RGSC_v3.41532,638,453 - 32,638,707UniSTSRGSC3.4
RGSC_v3.11532,654,153 - 32,654,407RGD
Celera1527,611,261 - 27,611,582UniSTS
RH 3.4 Map15201.0RGD
RH 3.4 Map15201.0UniSTS
RH 2.0 Map15173.8RGD
SHRSP x BN Map1525.6598RGD
Cytogenetic Map15p13UniSTS
RH131975  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,019,869 - 28,020,077 (+)MAPPERmRatBN7.2
mRatBN7.25139,221,340 - 139,221,548 (-)MAPPERmRatBN7.2
mRatBN7.25139,221,340 - 139,221,548 (+)MAPPERmRatBN7.2
mRatBN7.21528,019,869 - 28,020,077 (-)MAPPERmRatBN7.2
Rnor_6.01533,208,305 - 33,208,512NCBIRnor6.0
Rnor_6.05144,953,185 - 144,953,392NCBIRnor6.0
Rnor_5.05148,723,437 - 148,723,644UniSTSRnor5.0
Rnor_5.01537,092,394 - 37,092,601UniSTSRnor5.0
RGSC_v3.45146,342,495 - 146,342,702UniSTSRGSC3.4
RGSC_v3.41532,627,728 - 32,627,935UniSTSRGSC3.4
Celera1527,595,990 - 27,596,197UniSTS
Celera5137,716,397 - 137,716,604UniSTS
Cytogenetic Map15p13UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 28 10 10 10 31 34 36 11
Low 3 15 47 31 19 31 8 11 43 1 5 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000017753   ⟹   ENSRNOP00000017753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1528,019,778 - 28,030,021 (-)Ensembl
Rnor_6.0 Ensembl1533,208,216 - 33,218,456 (-)Ensembl
RefSeq Acc Id: NM_053503   ⟹   NP_445955
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,989,796 - 32,000,042 (-)NCBI
mRatBN7.21528,019,775 - 28,030,021 (-)NCBI
Rnor_6.01533,208,210 - 33,218,456 (-)NCBI
Rnor_5.01537,092,299 - 37,103,304 (-)NCBI
RGSC_v3.41532,627,633 - 32,637,861 (-)RGD
Celera1527,595,895 - 27,610,669 (-)RGD
Sequence:
RefSeq Acc Id: XM_063274732   ⟹   XP_063130802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,989,796 - 31,995,461 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_445955   ⟸   NM_053503
- UniProtKB: Q99ND4 (UniProtKB/Swiss-Prot),   Q5U2Z2 (UniProtKB/Swiss-Prot),   A6KGU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000017753   ⟸   ENSRNOT00000017753
RefSeq Acc Id: XP_063130802   ⟸   XM_063274732
- Peptide Label: isoform X1
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2Z2-F1-model_v2 AlphaFold Q5U2Z2 1-548 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699654
Promoter ID:EPDNEW_R10177
Type:single initiation site
Name:Ajuba_1
Description:ajuba LIM protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01533,218,422 - 33,218,482EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620407 AgrOrtholog
BioCyc Gene G2FUF-13794 BioCyc
Ensembl Genes ENSRNOG00000012791 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055012018 UniProtKB/Swiss-Prot
  ENSRNOG00060023233 UniProtKB/Swiss-Prot
  ENSRNOG00065031012 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017753 ENTREZGENE
  ENSRNOT00000017753.6 UniProtKB/Swiss-Prot
  ENSRNOT00055020424 UniProtKB/Swiss-Prot
  ENSRNOT00060040174 UniProtKB/Swiss-Prot
  ENSRNOT00065053463 UniProtKB/Swiss-Prot
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7110970 IMAGE-MGC_LOAD
InterPro Ajuba-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ajuba-like_LIM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ajuba-like_LIM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ajuba-like_LIM3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:85265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93830 IMAGE-MGC_LOAD
NCBI Gene 85265 ENTREZGENE
PANTHER LIM DOMAIN-CONTAINING PROTEIN AJUBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM DOMAIN-CONTAINING PROTEIN JUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ajuba PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012791 RatGTEx
  ENSRNOG00055012018 RatGTEx
  ENSRNOG00060023233 RatGTEx
  ENSRNOG00065031012 RatGTEx
SMART LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6KGU9 ENTREZGENE, UniProtKB/TrEMBL
  AJUBA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q99ND4 ENTREZGENE
UniProt Secondary Q99ND4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-06 Ajuba  ajuba LIM protein  Jub  jub, ajuba homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Jub  jub, ajuba homolog (Xenopus laevis)  Jub  ajuba  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Jub  ajuba  Jub  ajuba homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Jub  ajuba homolog (Xenopus laevis)    Ajuba protein  Name updated 1299863 APPROVED
2002-08-07 Jub  Ajuba protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes to the cytoplasm and translocates to the plasma membrane