Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC1A6 mRNA | CTD | PMID:17942748 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC1A6 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Slc1a6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC1A6 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-hydroxypropanoic acid | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of SLC1A6 mRNA | CTD | PMID:30851411 | 3,4-dichloroaniline | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | 3 and 4-dichloroaniline results in decreased expression of SLC1A6 mRNA | CTD | PMID:24172598 | 4,4'-sulfonyldiphenol | decreases expression | ISO | Slc1a6 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of SLC1A6 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SLC1A6 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SLC1A6 mRNA | CTD | PMID:24780913 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SLC1A6 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of SLC1A6 mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SLC1A6 mRNA | CTD | PMID:21934132 | all-trans-retinoic acid | affects expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Tretinoin affects the expression of SLC1A6 mRNA | CTD | PMID:15498508 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SLC1A6 mRNA | CTD | PMID:16483693 | androgen antagonist | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A6 mRNA | CTD | PMID:25607892 | arsenite(3-) | decreases expression | ISO | Slc1a6 (Mus musculus) | 6480464 | arsenite results in decreased expression of SLC1A6 mRNA | CTD | PMID:33053406 | benzo[a]pyrene | increases methylation | ISO | SLC1A6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SLC1A6 exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | SLC1A6 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC1A6 promoter | CTD | PMID:27901495 | bis(2-chloroethyl) sulfide | increases expression | ISO | Slc1a6 (Mus musculus) | 6480464 | Mustard Gas results in increased expression of SLC1A6 mRNA | CTD | PMID:15674843 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | bis(2-ethylhexyl) phthalate | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of SLC1A6 mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SLC1A6 mRNA more ... | CTD | PMID:25607892 more ... | bisphenol A | decreases expression | ISO | Slc1a6 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SLC1A6 mRNA | CTD | PMID:30951980 | bisphenol F | decreases expression | ISO | Slc1a6 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of SLC1A6 mRNA | CTD | PMID:30951980 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SLC1A6 mRNA | CTD | PMID:36041667 | Butylparaben | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A6 mRNA | CTD | PMID:25607892 | calcitriol | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of SLC1A6 mRNA | CTD | PMID:16002434 | CGP 52608 | multiple interactions | ISO | SLC1A6 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLC1A6 gene] | CTD | PMID:28238834 | chlorpyrifos | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [Chlorpyrifos co-treated with NGF protein] results in increased expression of SLC1A6 mRNA | CTD | PMID:20600679 | DDE | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | dextran sulfate | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC1A6 mRNA | CTD | PMID:29950665 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of SLC1A6 mRNA | CTD | PMID:18636392 | diuron | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Diuron metabolite results in increased expression of SLC1A6 mRNA | CTD | PMID:24172598 | dorsomorphin | multiple interactions | ISO | SLC1A6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of SLC1A6 mRNA | CTD | PMID:29391264 | enzacamene | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A6 mRNA | CTD | PMID:25607892 | epoxiconazole | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of SLC1A6 mRNA | CTD | PMID:20655511 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of SLC1A6 mRNA | CTD | PMID:30307764 | folic acid | increases expression | ISO | Slc1a6 (Mus musculus) | 6480464 | Folic Acid results in increased expression of SLC1A6 mRNA | CTD | PMID:25629700 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of SLC1A6 mRNA | CTD | PMID:25539665 | glycidol | increases expression | EXP | | 6480464 | glycidol results in increased expression of SLC1A6 mRNA | CTD | PMID:24395379 | indometacin | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Indomethacin results in increased expression of SLC1A6 mRNA | CTD | PMID:24737281 | lead(0) | affects expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Lead affects the expression of SLC1A6 mRNA | CTD | PMID:28903495 | linuron | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | lipopolysaccharide | increases expression | ISO | Slc1a6 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of SLC1A6 mRNA | CTD | PMID:12057914 | methoxychlor | increases methylation | EXP | | 6480464 | Methoxychlor results in increased methylation of SLC1A6 gene | CTD | PMID:23303685 | omega-6 fatty acid | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Fatty Acids and Omega-6 results in decreased expression of SLC1A6 mRNA | CTD | PMID:16823509 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of SLC1A6 mRNA | CTD | PMID:18636392 | paracetamol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A6 mRNA | CTD | PMID:25607892 | PCB138 | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | phenylmercury acetate | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of SLC1A6 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | SLC1A6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC1A6 mRNA | CTD | PMID:27188386 | potassium dichromate | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of SLC1A6 mRNA | CTD | PMID:11678601 | prochloraz | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | procymidone | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | rac-lactic acid | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of SLC1A6 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | SLC1A6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SLC1A6 mRNA | CTD | PMID:34032870 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of SLC1A6 mRNA | CTD | PMID:19281266 | tamibarotene | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | tamibarotene results in decreased expression of SLC1A6 mRNA | CTD | PMID:15498508 | tetrachloromethane | affects expression | ISO | Slc1a6 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of SLC1A6 mRNA | CTD | PMID:17484886 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of SLC1A6 mRNA | CTD | PMID:30723492 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of SLC1A6 mRNA | CTD | PMID:12734012 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SLC1A6 mRNA | CTD | PMID:23411599 | titanium dioxide | multiple interactions | ISO | Slc1a6 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC1A6 mRNA | CTD | PMID:29950665 | tributylstannane | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in decreased expression of SLC1A6 mRNA | CTD | PMID:31129395 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of SLC1A6 gene | CTD | PMID:27618143 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SLC1A6 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of SLC1A6 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | SLC1A6 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC1A6 mRNA | CTD | PMID:27188386 | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of SLC1A6 mRNA | CTD | PMID:30589522 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of SLC1A6 mRNA | CTD | PMID:32428529 | valproic acid | multiple interactions | ISO | SLC1A6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC1A6 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SLC1A6 mRNA | CTD | PMID:23179753 more ... | valproic acid | increases expression | ISO | SLC1A6 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SLC1A6 mRNA | CTD | PMID:24935251 | vinclozolin | multiple interactions | EXP | | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA | CTD | PMID:25607892 | |