Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Ppig (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PPIG mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ppig (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PPIG mRNA | CTD | PMID:18691609 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PPIG mRNA | CTD | PMID:34747641 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of PPIG mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of PPIG mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Ppig (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PPIG mRNA | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | PPIG (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of PPIG gene | CTD | PMID:31601247 | acetylsalicylic acid | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | Aspirin results in increased expression of PPIG mRNA | CTD | PMID:15928584 | allethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of PPIG protein | CTD | PMID:34896426 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PPIG mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of PPIG mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PPIG mRNA | CTD | PMID:33212167 | arsenous acid | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PPIG mRNA | CTD | PMID:20458559 | asbestos | affects expression | ISO | PPIG (Homo sapiens) | 6480464 | Asbestos affects the expression of PPIG mRNA | CTD | PMID:17297452 | benzo[a]pyrene | multiple interactions | ISO | Ppig (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PPIG mRNA | CTD | PMID:27858113 | benzo[a]pyrene | decreases methylation | ISO | PPIG (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PPIG promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | benzo[b]fluoranthene | multiple interactions | ISO | Ppig (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PPIG mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PPIG mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases expression | ISO | Ppig (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PPIG mRNA | CTD | PMID:33221593 | cadmium dichloride | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of PPIG mRNA | CTD | PMID:25596134 | caffeine | affects phosphorylation | ISO | PPIG (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of PPIG protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | ISO | Ppig (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of PPIG mRNA | CTD | PMID:25554681 | chloroacetaldehyde | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | chloroacetaldehyde results in decreased expression of PPIG mRNA | CTD | PMID:25596134 | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of PPIG mRNA | CTD | PMID:23125180 | chlorpyrifos | decreases expression | ISO | Ppig (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of PPIG mRNA | CTD | PMID:37019170 | chrysene | multiple interactions | ISO | Ppig (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PPIG mRNA | CTD | PMID:27858113 | cidofovir anhydrous | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Cidofovir results in decreased expression of PPIG mRNA | CTD | PMID:25596134 | cisplatin | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of PPIG mRNA | CTD | PMID:25596134 | clodronic acid | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Clodronic Acid results in decreased expression of PPIG mRNA | CTD | PMID:25596134 | coumarin | affects phosphorylation | ISO | PPIG (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of PPIG protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PPIG mRNA | CTD | PMID:25562108 | cyhalothrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of PPIG protein | CTD | PMID:34896426 | cypermethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of PPIG protein | CTD | PMID:34896426 | diarsenic trioxide | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PPIG mRNA | CTD | PMID:20458559 | dibutyl phthalate | affects expression | EXP | | 6480464 | Dibutyl Phthalate affects the expression of PPIG mRNA | CTD | PMID:30934153 | dicrotophos | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of PPIG mRNA | CTD | PMID:28302478 | dioxygen | affects expression | ISO | PPIG (Homo sapiens) | 6480464 | Oxygen deficiency affects the expression of PPIG mRNA | CTD | PMID:25596134 | dorsomorphin | multiple interactions | ISO | PPIG (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPIG mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of PPIG mRNA | CTD | PMID:29803840 | elemental selenium | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Selenium results in decreased expression of PPIG mRNA | CTD | PMID:19244175 | enzyme inhibitor | multiple interactions | ISO | PPIG (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PPIG protein | CTD | PMID:23301498 | ethanol | affects splicing | ISO | Ppig (Mus musculus) | 6480464 | Ethanol affects the splicing of PPIG mRNA | CTD | PMID:30319688 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of PPIG mRNA | CTD | PMID:30307764 | fenvalerate | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of PPIG protein | CTD | PMID:34896426 | folic acid | multiple interactions | ISO | Ppig (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PPIG mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of PPIG mRNA | CTD | PMID:23649840 | FR900359 | increases phosphorylation | ISO | PPIG (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of PPIG protein | CTD | PMID:37730182 | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of PPIG protein | CTD | PMID:24552547 | ifosfamide | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Ifosfamide results in decreased expression of PPIG mRNA | CTD | PMID:25596134 | ivermectin | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PPIG protein | CTD | PMID:32959892 | N(6)-dimethylallyladenine | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | N(6)-(delta(2)-isopentenyl)adenine results in increased expression of PPIG mRNA | CTD | PMID:16129123 | paracetamol | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PPIG mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PPIG mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PPIG mRNA | CTD | PMID:27153767 | phenobarbital | decreases expression | ISO | Ppig (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of PPIG mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of PPIG mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | PPIG (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPIG mRNA | CTD | PMID:27188386 | pyrethrins | affects expression | EXP | | 6480464 | Pyrethrins affects the expression of PPIG protein | CTD | PMID:34896426 | SB 431542 | multiple interactions | ISO | PPIG (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPIG mRNA | CTD | PMID:27188386 | selenium atom | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Selenium results in decreased expression of PPIG mRNA | CTD | PMID:19244175 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of PPIG mRNA | CTD | PMID:19281266 | sunitinib | increases expression | ISO | PPIG (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PPIG mRNA | CTD | PMID:31533062 | testosterone enanthate | affects expression | ISO | PPIG (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of PPIG mRNA | CTD | PMID:17440010 | tetraphene | multiple interactions | ISO | Ppig (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PPIG mRNA | CTD | PMID:27858113 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of PPIG mRNA | CTD | PMID:33387578 | triptonide | increases expression | ISO | Ppig (Mus musculus) | 6480464 | triptonide results in increased expression of PPIG mRNA | CTD | PMID:33045310 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of PPIG mRNA | CTD | PMID:21318169 | valproic acid | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PPIG mRNA | CTD | PMID:23179753 more ... | vitamin E | decreases expression | ISO | PPIG (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of PPIG mRNA | CTD | PMID:19244175 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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