Gene: Abcc4 (ATP binding cassette subfamily C member 4) Rattus norvegicus
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Symbol: Abcc4
Name: ATP binding cassette subfamily C member 4
Description: ENCODES a protein that exhibits ATP binding (inferred); ATPase activity, coupled to transmembrane movement of substances (inferred); INVOLVED IN positive regulation of smooth muscle cell proliferation; response to drug; response to organic cyclic compound; PARTICIPATES IN azathioprine pharmacodynamics pathway; lamivudine pharmacokinetics pathway; mercaptopurine pharmacodynamics pathway; ASSOCIATED WITH Cholestasis; cholestasis; Arthritis, Rheumatoid (ortholog); FOUND IN basolateral plasma membrane; membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (-)-epigallocatechin 3-gallate; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ABC-tranporter; ATP-binding cassette protein C4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4; LOC306166; Mrp4; multidrug resistance-associated protein 4; RGD1565953; similar to multidrug resistance-associated protein 4
Orthologs:
Homo sapiens (human) : ABCC4 (ATP binding cassette subfamily C member 4)  HGNC  AGR
Mus musculus (house mouse) : Abcc4 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Abcc4 (ATP binding cassette subfamily C member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCC4 (ATP binding cassette subfamily C member 4)
Canis lupus familiaris (dog) : ABCC4 (ATP binding cassette subfamily C member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc4 (ATP binding cassette subfamily C member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.015103,695,415 - 103,927,980 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.015107,127,408 - 107,356,997 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.415103,384,848 - 103,611,238 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.115103,416,404 - 103,417,006 (-)NCBI
Celera1594,392,176 - 94,624,412 (-)NCBI
Cytogenetic Map15q24NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
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RGD Object Information
RGD ID: 620266
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE