Fgf12 (fibroblast growth factor 12) - Rat Genome Database

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Gene: Fgf12 (fibroblast growth factor 12) Rattus norvegicus
Analyze
Symbol: Fgf12
Name: fibroblast growth factor 12
RGD ID: 620163
Description: Enables sodium channel regulator activity and transmembrane transporter binding activity. Involved in regulation of membrane depolarization and regulation of sodium ion transmembrane transport. Predicted to be located in synapse. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 47. Orthologous to human FGF12 (fibroblast growth factor 12); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FGF-12; Fgf1a; FHF-1; Fhf1; Fhf1b; fibroblast growth factor 1a; fibroblast growth factor homologous factor 1; fibroblast growth factor homologous factor 1b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81185,501,947 - 86,069,543 (+)NCBIGRCr8
mRatBN7.21171,997,151 - 72,564,757 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1171,997,099 - 72,562,607 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1180,835,781 - 81,403,369 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01173,470,763 - 74,038,380 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01172,528,137 - 73,092,997 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01175,606,360 - 76,171,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1175,905,443 - 76,168,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01178,647,628 - 79,212,339 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,208,696 - 74,481,037 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11174,266,284 - 74,538,626 (+)NCBI
Celera1171,257,632 - 71,518,401 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cannabidiol  (EXP)
choline  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dieldrin  (EXP)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
fonofos  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
indole-3-methanol  (EXP)
kojic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
O-methyleugenol  (ISO)
paracetamol  (EXP)
parathion  (ISO)
PCB138  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
nucleus  (IBA,IEA,ISO)
synapse  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN). Liu Cj, etal., J Biol Chem 2001 Jun 1;276(22):18925-33.
3. Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B. Liu CJ, etal., J Biol Chem. 2003 Jan 10;278(2):1029-36. Epub 2002 Oct 24.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs. Olsen SK, etal., J Biol Chem 2003 Sep 5;278(36):34226-36. Epub 2003 Jun 17.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8790420   PMID:17678857   PMID:25724910   PMID:27164707   PMID:27470512   PMID:35093630  


Genomics

Comparative Map Data
Fgf12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81185,501,947 - 86,069,543 (+)NCBIGRCr8
mRatBN7.21171,997,151 - 72,564,757 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1171,997,099 - 72,562,607 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1180,835,781 - 81,403,369 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01173,470,763 - 74,038,380 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01172,528,137 - 73,092,997 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01175,606,360 - 76,171,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1175,905,443 - 76,168,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01178,647,628 - 79,212,339 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,208,696 - 74,481,037 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11174,266,284 - 74,538,626 (+)NCBI
Celera1171,257,632 - 71,518,401 (+)NCBICelera
Cytogenetic Map11q22NCBI
FGF12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383192,139,390 - 192,727,541 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3192,139,390 - 192,767,764 (-)EnsemblGRCh38hg38GRCh38
GRCh373191,857,179 - 192,445,330 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363193,342,413 - 193,928,066 (-)NCBINCBI36Build 36hg18NCBI36
Build 343193,342,427 - 193,608,714NCBI
Celera3190,287,307 - 190,871,367 (-)NCBICelera
Cytogenetic Map3q28-q29NCBI
HuRef3189,257,496 - 189,843,496 (-)NCBIHuRef
CHM1_13191,820,291 - 192,408,216 (-)NCBICHM1_1
T2T-CHM13v2.03194,835,241 - 195,423,480 (-)NCBIT2T-CHM13v2.0
Fgf12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391627,976,535 - 28,571,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1627,978,850 - 28,571,820 (-)EnsemblGRCm39 Ensembl
GRCm381628,157,783 - 28,753,243 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1628,160,098 - 28,753,068 (-)EnsemblGRCm38mm10GRCm38
MGSCv371628,160,184 - 28,753,288 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361628,075,331 - 28,672,949 (-)NCBIMGSCv36mm8
Celera1628,680,820 - 29,265,446 (-)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1619.38NCBI
Fgf12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542016,070,096 - 16,306,103 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542015,783,184 - 16,310,743 (+)NCBIChiLan1.0ChiLan1.0
FGF12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22190,077,177 - 190,666,458 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13190,081,896 - 190,669,838 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03189,430,811 - 190,017,254 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13199,776,475 - 200,359,141 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3199,778,545 - 200,358,744 (-)Ensemblpanpan1.1panPan2
FGF12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13423,818,445 - 24,357,825 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3423,819,686 - 24,357,373 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3427,906,449 - 28,448,823 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03423,761,357 - 24,303,983 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3423,764,444 - 24,302,991 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13423,789,790 - 24,338,922 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03423,765,747 - 24,309,079 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03424,006,536 - 24,549,544 (-)NCBIUU_Cfam_GSD_1.0
Fgf12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602121,869,101 - 122,376,824 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367112,045,080 - 2,375,896 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367111,873,030 - 2,378,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13129,240,083 - 129,817,911 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113129,237,500 - 129,817,992 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213138,752,214 - 138,983,183 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11586,252,816 - 86,836,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604159,914,424 - 60,500,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473065,038,077 - 65,284,083 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473064,743,724 - 65,288,816 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fgf12
4573 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000002650, ENSRNOT00000071586
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat

Markers in Region
D11Mco1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,373,932 - 72,374,168 (+)MAPPERmRatBN7.2
Rnor_6.01175,980,425 - 75,980,660NCBIRnor6.0
Rnor_5.01179,022,025 - 79,022,260UniSTSRnor5.0
RGSC_v3.41174,287,096 - 74,287,332RGDRGSC3.4
RGSC_v3.41174,287,097 - 74,287,332UniSTSRGSC3.4
RGSC_v3.11174,344,685 - 74,344,921RGD
Celera1171,329,739 - 71,329,974UniSTS
Cytogenetic Map11q22UniSTS
D11Arb13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,453,971 - 72,454,154 (+)MAPPERmRatBN7.2
Rnor_6.01176,060,599 - 76,060,781NCBIRnor6.0
Rnor_5.01179,102,266 - 79,102,448UniSTSRnor5.0
RGSC_v3.41174,367,678 - 74,367,862RGDRGSC3.4
RGSC_v3.41174,367,680 - 74,367,862UniSTSRGSC3.4
RGSC_v3.11174,425,267 - 74,425,451RGD
Celera1171,409,911 - 71,410,093UniSTS
Cytogenetic Map11q22UniSTS
D11Got112  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,462,243 - 72,462,449 (+)MAPPERmRatBN7.2
Rnor_6.01176,068,871 - 76,069,076NCBIRnor6.0
Rnor_5.01179,110,538 - 79,110,743UniSTSRnor5.0
RGSC_v3.41174,375,952 - 74,376,157UniSTSRGSC3.4
Celera1171,418,099 - 71,418,304UniSTS
Cytogenetic Map11q22UniSTS
RH142893  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,302,653 - 72,302,765 (+)MAPPERmRatBN7.2
Rnor_6.01175,909,150 - 75,909,261NCBIRnor6.0
Rnor_5.01178,950,750 - 78,950,861UniSTSRnor5.0
RGSC_v3.41174,212,403 - 74,212,514UniSTSRGSC3.4
Celera1171,261,339 - 71,261,450UniSTS
RH 3.4 Map11580.9UniSTS
Cytogenetic Map11q22UniSTS
BF397888  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,413,923 - 72,414,074 (+)MAPPERmRatBN7.2
Rnor_6.01176,020,547 - 76,020,697NCBIRnor6.0
Rnor_5.01179,062,147 - 79,062,297UniSTSRnor5.0
RGSC_v3.41174,327,526 - 74,327,676UniSTSRGSC3.4
Celera1171,369,806 - 71,369,956UniSTS
RH 3.4 Map11595.9UniSTS
Cytogenetic Map11q22UniSTS
RH140156  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,562,547 - 72,562,748 (+)MAPPERmRatBN7.2
Rnor_6.01176,168,871 - 76,169,071NCBIRnor6.0
Rnor_5.01179,210,132 - 79,210,332UniSTSRnor5.0
RGSC_v3.41174,481,117 - 74,481,317UniSTSRGSC3.4
Celera1171,518,481 - 71,518,681UniSTS
Cytogenetic Map11q22UniSTS
RH140530  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,562,505 - 72,562,664 (+)MAPPERmRatBN7.2
Rnor_6.01176,168,829 - 76,168,987NCBIRnor6.0
Rnor_5.01179,210,090 - 79,210,248UniSTSRnor5.0
RGSC_v3.41174,481,075 - 74,481,233UniSTSRGSC3.4
Celera1171,518,439 - 71,518,597UniSTS
RH 3.4 Map11593.5UniSTS
Cytogenetic Map11q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 68 18 19 1
Low 3 40 24 19 24 8 10 6 17 22 10 8
Below cutoff 17 17 17 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002650   ⟹   ENSRNOP00000002650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1171,997,099 - 72,562,607 (+)Ensembl
Rnor_6.0 Ensembl1175,905,443 - 76,168,791 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000071586   ⟹   ENSRNOP00000066842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1172,540,927 - 72,562,607 (+)Ensembl
Rnor_6.0 Ensembl1176,147,205 - 76,168,989 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112688   ⟹   ENSRNOP00000085066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1172,186,031 - 72,562,607 (+)Ensembl
RefSeq Acc Id: NM_001395084   ⟹   NP_001382013
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81185,501,947 - 86,069,543 (+)NCBI
mRatBN7.21171,997,151 - 72,564,757 (+)NCBI
RefSeq Acc Id: NM_130814   ⟹   NP_570827
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81185,801,758 - 86,069,543 (+)NCBI
mRatBN7.21172,296,990 - 72,564,757 (+)NCBI
Rnor_6.01175,905,443 - 76,168,791 (+)NCBI
Rnor_5.01178,647,628 - 79,212,339 (+)NCBI
RGSC_v3.41174,208,696 - 74,481,037 (+)RGD
Celera1171,257,632 - 71,518,401 (+)RGD
Sequence:
RefSeq Acc Id: XM_017597854   ⟹   XP_017453343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81185,693,335 - 86,069,543 (+)NCBI
mRatBN7.21172,188,575 - 72,564,757 (+)NCBI
Rnor_6.01175,795,160 - 76,171,078 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_570827   ⟸   NM_130814
- Peptide Label: isoform 1
- UniProtKB: P61150 (UniProtKB/Swiss-Prot),   A0A7U3L6G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453343   ⟸   XM_017597854
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2F9 (UniProtKB/TrEMBL),   A6JRX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002650   ⟸   ENSRNOT00000002650
RefSeq Acc Id: ENSRNOP00000066842   ⟸   ENSRNOT00000071586
RefSeq Acc Id: ENSRNOP00000085066   ⟸   ENSRNOT00000112688
RefSeq Acc Id: NP_001382013   ⟸   NM_001395084
- Peptide Label: isoform 2
- UniProtKB: A6JRX5 (UniProtKB/TrEMBL),   A6JRX6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61150-F1-model_v2 AlphaFold P61150 1-243 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620163 AgrOrtholog
BioCyc Gene G2FUF-20959 BioCyc
Ensembl Genes ENSRNOG00000001931 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055004637 UniProtKB/Swiss-Prot
  ENSRNOG00060024257 UniProtKB/Swiss-Prot
  ENSRNOG00065003574 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002650 ENTREZGENE
  ENSRNOT00000002650.5 UniProtKB/Swiss-Prot
  ENSRNOT00000071586.3 UniProtKB/TrEMBL
  ENSRNOT00000112688.1 UniProtKB/TrEMBL
  ENSRNOT00055007377 UniProtKB/Swiss-Prot
  ENSRNOT00060042054 UniProtKB/Swiss-Prot
  ENSRNOT00065005153 UniProtKB/Swiss-Prot
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Fibroblast_GF_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:170630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 170630 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11486:SF17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fgf12 PhenoGen
PRINTS HBGFFGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1HBGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001931 RatGTEx
  ENSRNOG00055004637 RatGTEx
  ENSRNOG00060024257 RatGTEx
  ENSRNOG00065003574 RatGTEx
SMART FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A7U3L6G2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2F9 ENTREZGENE, UniProtKB/TrEMBL
  A6JRX4_RAT UniProtKB/TrEMBL
  A6JRX5 ENTREZGENE, UniProtKB/TrEMBL
  A6JRX6 ENTREZGENE, UniProtKB/TrEMBL
  FGF12_RAT UniProtKB/Swiss-Prot
  M0RBB2_RAT UniProtKB/TrEMBL
  P61150 ENTREZGENE
UniProt Secondary O35339 UniProtKB/Swiss-Prot
  P70376 UniProtKB/Swiss-Prot
  Q924B4 UniProtKB/Swiss-Prot
  Q92912 UniProtKB/Swiss-Prot
  Q93001 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-08-06 Fgf12  fibroblast growth factor 12      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN) 632803
gene_product member of the fibroblast growth factor family 632803