Gene: Park2 (parkin RBR E3 ubiquitin protein ligase) Rattus norvegicus
Symbol: Park2
Name: parkin RBR E3 ubiquitin protein ligase
Description: ENCODES a protein that exhibits protein complex binding; actin binding (ortholog); beta-catenin binding (ortholog); INVOLVED IN cellular response to manganese ion; mitochondrion localization; mitophagy; PARTICIPATES IN altered mitochondrial autophagy pathway; altered ubiquitin/proteasome degradation pathway; mitochondrial autophagy pathway; ASSOCIATED WITH Adenocarcinoma of Lung (ortholog); Alzheimer Disease (ortholog); Frontotemporal Dementia (ortholog); FOUND IN cytoplasm; cytoplasmic vesicle; cytosol; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; Aroclor 1254
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase parkin; Park; parkin; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkinson protein 2, E3 ubiquitin protein ligase; Prkn
Orthologs:
Allele / Splice: Park2em1Sage  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0148,880,015 - 50,069,998 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0149,684,308 - 50,875,397 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4143,151,265 - 44,374,470 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1143,154,209 - 44,377,415 (-)NCBI
Celera144,478,407 - 45,666,902 (-)NCBI
Cytogenetic Map1q11NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Park2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 61797
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2016-06-14
Status: ACTIVE