(-)-selegiline multiple interactions ISO PRKN (Homo sapiens) 6480464 Selegiline inhibits the reaction [linsidomine results in increased expression of PRKN protein] CTD PMID:12880480 (1->4)-beta-D-glucan multiple interactions ISO Prkn (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRKN mRNA CTD PMID:36331819 (R)-lipoic acid multiple interactions ISO Prkn (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Sodium Fluoride results in increased expression of PRKN mRNA] CTD PMID:37739047 (S)-nicotine decreases expression ISO PRKN (Homo sapiens) 6480464 Nicotine results in decreased expression of PRKN mRNA CTD PMID:16949557 1,2-dimethylhydrazine decreases expression ISO Prkn (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PARK2 mRNA CTD PMID:22206623 1,3-dichloropropan-2-ol decreases expression EXP 6480464 1 and 3-dichloro-2-propanol results in decreased expression of PARK protein CTD PMID:36000575 1,4-benzoquinone increases expression ISO PRKN (Homo sapiens) 6480464 quinone results in increased expression of PRKN mRNA and quinone results in increased expression of PRKN protein CTD PMID:29567065 1,4-benzoquinone multiple interactions ISO PRKN (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [quinone results in increased expression of PRKN protein] more ... CTD PMID:29567065 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN protein inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:25447324 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Prkn (Mus musculus) 6480464 AM 1241 inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:22511790 and PMID:28978077 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases response to substance ISO Prkn (Mus musculus) 6480464 PRKN protein results in decreased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:23643664 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Prkn (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:23643664 and PMID:28978077 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO Prkn (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:22342763 and PMID:27566062 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Prkn (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PRKN mRNA CTD PMID:21570461 3-BROMO-7-NITROINDAZOLE multiple interactions ISO Prkn (Mus musculus) 6480464 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein] CTD PMID:23985028 4,4'-sulfonyldiphenol decreases expression ISO Prkn (Mus musculus) 6480464 bisphenol S results in decreased expression of PARK2 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol decreases methylation ISO PRKN (Homo sapiens) 6480464 bisphenol S results in decreased methylation of PRKN gene CTD PMID:31601247 4,5,6,7-TETRABROMOBENZOTRIAZOLE multiple interactions ISO PRKN (Homo sapiens) 6480464 4 more ... CTD PMID:37156403 4-hydroxy-TEMPO multiple interactions EXP 6480464 tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA] and tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN protein] CTD PMID:25787151 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of PRKN mRNA CTD PMID:24780913 acetaldehyde decreases expression ISO PRKN (Homo sapiens) 6480464 Acetaldehyde results in decreased expression of PRKN mRNA and Acetaldehyde results in decreased expression of PRKN protein CTD PMID:35595033 acetaldehyde multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN protein inhibits the reaction [Acetaldehyde results in decreased expression of FTH1 protein] more ... CTD PMID:35595033 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of PRKN mRNA CTD PMID:31881176 acetylcholine multiple interactions ISO Prkn (Mus musculus) 6480464 Acetylcholine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN protein] CTD PMID:34547296 aflatoxin B1 decreases methylation ISO PRKN (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PRKN gene CTD PMID:27153756 aflatoxin B1 multiple interactions ISO Prkn (Mus musculus) 6480464 PRKN protein affects the reaction [Aflatoxin B1 results in decreased expression of BCL2 protein] more ... CTD PMID:35304092 aflatoxin B1 increases expression ISO Prkn (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of PRKN mRNA and Aflatoxin B1 results in increased expression of PRKN protein CTD PMID:35304092 aflatoxin B1 affects methylation ISO PRKN (Homo sapiens) 6480464 Aflatoxin B1 affects the methylation of PRKN intron CTD PMID:30157460 aflatoxin B1 decreases expression ISO PRKN (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PARK2 mRNA and Aflatoxin B1 results in decreased expression of PRKN mRNA CTD PMID:31555880 more ... Aflatoxin B2 alpha affects methylation ISO PRKN (Homo sapiens) 6480464 aflatoxin B2 affects the methylation of PRKN intron CTD PMID:30157460 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PRKN protein CTD PMID:35243728 aldehydo-D-glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 all-trans-retinoic acid multiple interactions ISO PRKN (Homo sapiens) 6480464 Tretinoin affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of PRKN protein alternative form] more ... CTD PMID:28688199 aluminium atom multiple interactions ISO Prkn (Mus musculus) 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA more ... CTD PMID:34547296 aluminium(0) multiple interactions ISO Prkn (Mus musculus) 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA more ... CTD PMID:34547296 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PRKN mRNA CTD PMID:16483693 amphetamine increases response to substance ISO Prkn (Mus musculus) 6480464 PRKN protein results in increased susceptibility to Amphetamine CTD PMID:12915482 amphetamine multiple interactions ISO Prkn (Mus musculus) 6480464 PRKN protein promotes the reaction [Amphetamine results in increased abundance of Dopamine] CTD PMID:12915482 androgen antagonist multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA CTD PMID:25607892 antimycin A multiple interactions ISO PRKN (Homo sapiens) 6480464 [oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein more ... CTD PMID:28366621 and PMID:28673964 antimycin A decreases expression ISO PRKN (Homo sapiens) 6480464 Antimycin A results in decreased expression of PRKN mRNA CTD PMID:33512557 antirheumatic drug increases expression ISO PRKN (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of PRKN mRNA CTD PMID:24449571 aristolochic acid A decreases expression ISO PRKN (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PRKN mRNA CTD PMID:33212167 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of PRKN protein CTD PMID:16174552 arsane affects methylation ISO PRKN (Homo sapiens) 6480464 Arsenic affects the methylation of PRKN gene CTD PMID:25304211 arsenic atom affects methylation ISO PRKN (Homo sapiens) 6480464 Arsenic affects the methylation of PRKN gene CTD PMID:25304211 arsenous acid multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PRKN protein] CTD PMID:30551535 arsenous acid affects localization ISO Prkn (Mus musculus) 6480464 Arsenic Trioxide affects the localization of PRKN protein CTD PMID:24801902 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PRKN protein CTD PMID:30551535 atrazine increases expression EXP 6480464 Atrazine results in increased expression of PRKN mRNA and Atrazine results in increased expression of PRKN protein CTD PMID:30084861 azoxystrobin decreases expression ISO PRKN (Homo sapiens) 6480464 azoxystrobin results in decreased expression of PRKN mRNA CTD PMID:33512557 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PRKN protein CTD PMID:32619457 and PMID:36736873 benzo[a]pyrene multiple interactions EXP 6480464 [Resveratrol co-treated with Benzo(a)pyrene] results in increased expression of PRKN protein CTD PMID:32619457 benzo[a]pyrene affects methylation ISO PRKN (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PRKN intron CTD PMID:30157460 benzo[a]pyrene decreases expression ISO Prkn (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PRKN mRNA CTD PMID:21569818 benzo[a]pyrene decreases expression ISO PRKN (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PARK2 mRNA and Benzo(a)pyrene results in decreased expression of PRKN mRNA CTD PMID:31555880 more ... benzo[e]pyrene increases methylation ISO PRKN (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of PRKN intron CTD PMID:30157460 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 bis(2-ethylhexyl) phthalate multiple interactions ISO Prkn (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN mRNA] and Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN protein] CTD PMID:36583613 bis(2-ethylhexyl) phthalate increases expression ISO Prkn (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of PRKN mRNA and Diethylhexyl Phthalate results in increased expression of PRKN protein CTD PMID:36583613 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of PARK protein CTD PMID:37692514 bis(2-ethylhexyl) phthalate increases expression ISO PRKN (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of PRKN mRNA CTD PMID:34822940 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA and [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA CTD PMID:25607892 bisphenol A multiple interactions ISO PRKN (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRKN gene CTD PMID:31601247 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PRKN gene CTD PMID:28505145 bisphenol A decreases expression ISO Prkn (Mus musculus) 6480464 bisphenol A results in decreased expression of PARK2 mRNA CTD PMID:30951980 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PRKN mRNA CTD PMID:25181051 bupivacaine decreases expression ISO Prkn (Mus musculus) 6480464 Bupivacaine results in decreased expression of PRKN protein CTD PMID:34793778 bupivacaine multiple interactions ISO Prkn (Mus musculus) 6480464 HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PRKN protein] CTD PMID:34793778 Butylparaben multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA and [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA CTD PMID:25607892 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of PRKN mRNA CTD PMID:19167457 cadmium atom increases expression ISO Prkn (Mus musculus) 6480464 Cadmium results in increased expression of PRKN CTD PMID:25464205 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of PRKN mRNA CTD PMID:34816377 cadmium atom multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PRKN mRNA] CTD PMID:34816377 cadmium atom multiple interactions ISO PRKN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKN protein CTD PMID:32142837 cadmium atom multiple interactions ISO Prkn (Mus musculus) 6480464 3-(2 more ... CTD PMID:25464205 and PMID:34952138 cadmium dichloride multiple interactions ISO Prkn (Mus musculus) 6480464 3-(2 more ... CTD PMID:34952138 cadmium dichloride multiple interactions EXP 6480464 SIRT1 protein inhibits the reaction [Cadmium Chloride results in increased expression of PARK protein] CTD PMID:37451666 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of PARK protein CTD PMID:37451666 cadmium dichloride multiple interactions ISO PRKN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKN protein CTD PMID:32142837 cantharidin decreases expression ISO Prkn (Mus musculus) 6480464 Cantharidin results in decreased expression of PRKN mRNA CTD PMID:36907384 carbon nanotube decreases expression ISO Prkn (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 carbonyl cyanide p-trifluoromethoxyphenylhydrazone multiple interactions ISO Prkn (Mus musculus) 6480464 PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 carbonyl cyanide p-trifluoromethoxyphenylhydrazone affects localization ISO Prkn (Mus musculus) 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein CTD PMID:24879156 carnosic acid multiple interactions ISO PRKN (Homo sapiens) 6480464 PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]] more ... CTD PMID:30707903 and PMID:31705926 carnosic acid increases expression ISO PRKN (Homo sapiens) 6480464 salvin results in increased expression of PRKN protein CTD PMID:31705926 CCCP decreases response to substance ISO Prkn (Mus musculus) 6480464 PRKN protein results in decreased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone CTD PMID:16517603 CCCP increases response to substance ISO Prkn (Mus musculus) 6480464 PRKN gene mutant form results in increased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone CTD PMID:16517603 CCCP decreases expression ISO PRKN (Homo sapiens) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of PRKN protein CTD PMID:28688199 CCCP affects expression ISO PRKN (Homo sapiens) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form CTD PMID:28688199 CCCP increases phosphorylation ISO Prkn (Mus musculus) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein CTD PMID:29660402 CCCP multiple interactions ISO Prkn (Mus musculus) 6480464 1 more ... CTD PMID:22872702 and PMID:24879156 CCCP affects localization ISO Prkn (Mus musculus) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein CTD PMID:22872702 CCCP multiple interactions ISO PRKN (Homo sapiens) 6480464 [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein more ... CTD PMID:24879156 more ... CCCP affects localization ISO PRKN (Homo sapiens) 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein CTD PMID:22872702 more ... CCCP multiple interactions EXP 6480464 BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] more ... CTD PMID:24879156 CCCP affects localization EXP 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein CTD PMID:24879156 CCCP increases phosphorylation EXP 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein CTD PMID:24879156 CGP 52608 multiple interactions ISO PRKN (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PARK2 gene] CTD PMID:28238834 chloroquine multiple interactions ISO Prkn (Mus musculus) 6480464 Chloroquine inhibits the reaction [Acetaminophen results in increased expression of PRKN protein] and Chloroquine inhibits the reaction [coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PRKN protein]] CTD PMID:33271250 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein]] CTD PMID:35104487 chlorpyrifos affects localization ISO PRKN (Homo sapiens) 6480464 Chlorpyrifos affects the localization of PRKN protein CTD PMID:26070385 chlorpyrifos decreases expression ISO Prkn (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of PRKN mRNA CTD PMID:29156651 chlorpyrifos multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN protein inhibits the reaction [Chlorpyrifos results in decreased expression of NDUFS3 protein] more ... CTD PMID:26070385 chromium(6+) multiple interactions ISO PRKN (Homo sapiens) 6480464 HMGA2 protein promotes the reaction [chromium hexavalent ion results in increased expression of PRKN protein] CTD PMID:32866567 chromium(6+) increases expression ISO PRKN (Homo sapiens) 6480464 chromium hexavalent ion results in increased expression of PRKN protein CTD PMID:30715550 and PMID:32866567 chromium(6+) increases expression ISO Prkn (Mus musculus) 6480464 chromium hexavalent ion results in increased expression of PRKN protein CTD PMID:32866567 cinnarizine decreases response to substance ISO Prkn (Mus musculus) 6480464 PRKN results in decreased susceptibility to Cinnarizine CTD PMID:15993444 cisplatin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cisplatin results in increased expression of PRKN protein] CTD PMID:28698153 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PRKN protein CTD PMID:28698153 clothianidin decreases expression ISO PRKN (Homo sapiens) 6480464 clothianidin results in decreased expression of PARK2 mRNA CTD PMID:35690182 coenzyme Q10 multiple interactions ISO Prkn (Mus musculus) 6480464 Chloroquine inhibits the reaction [coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PRKN protein]] and coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PRKN protein] CTD PMID:33271250 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cisplatin results in increased expression of PRKN protein] CTD PMID:28698153 cyclosporin A multiple interactions ISO PRKN (Homo sapiens) 6480464 Cyclosporine inhibits the reaction [quinone results in increased expression of PRKN mRNA] and Cyclosporine inhibits the reaction [quinone results in increased expression of PRKN protein] CTD PMID:29567065 cyclosporin A multiple interactions ISO Prkn (Mus musculus) 6480464 Cyclosporine inhibits the reaction [Cadmium results in increased expression of PRKN] CTD PMID:25464205 D-glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PRKN protein CTD PMID:35243728 DDE multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 diarsenic trioxide affects localization ISO Prkn (Mus musculus) 6480464 Arsenic Trioxide affects the localization of PRKN protein CTD PMID:24801902 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PRKN protein CTD PMID:30551535 diarsenic trioxide multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PRKN protein] CTD PMID:30551535 diazinon decreases expression EXP 6480464 Diazinon results in decreased expression of PRKN mRNA CTD PMID:21968025 dibutyl phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 dieldrin increases response to substance ISO PRKN (Homo sapiens) 6480464 PARK2 gene mutant form results in increased susceptibility to Dieldrin CTD PMID:32421776 dioxygen multiple interactions ISO Prkn (Mus musculus) 6480464 [Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein more ... CTD PMID:28477916 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Oxygen] results in decreased expression of PRKN protein more ... CTD PMID:34358556 dopamine multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN protein inhibits the reaction [Dopamine results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:15198987 dopamine multiple interactions ISO Prkn (Mus musculus) 6480464 PRKN mutant form results in increased abundance of and results in increased metabolism of Dopamine more ... CTD PMID:12915482 and PMID:15993444 dopamine increases expression ISO PRKN (Homo sapiens) 6480464 Dopamine results in increased expression of PRKN mRNA CTD PMID:16987221 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [sappanone A inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of PRKN protein]] CTD PMID:34358556 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of PRKN protein CTD PMID:26678157 and PMID:29966675 doxorubicin increases expression ISO PRKN (Homo sapiens) 6480464 Doxorubicin results in increased expression of PRKN protein CTD PMID:29729358 doxorubicin decreases response to substance EXP 6480464 PRKN protein results in decreased susceptibility to Doxorubicin CTD PMID:32434049 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of PRKN mRNA and Doxorubicin results in decreased expression of PRKN protein CTD PMID:32434049 doxorubicin multiple interactions ISO PRKN (Homo sapiens) 6480464 3-(2 more ... CTD PMID:29729358 doxorubicin decreases expression ISO PRKN (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PRKN mRNA CTD PMID:29803840 doxorubicin decreases expression ISO Prkn (Mus musculus) 6480464 Doxorubicin results in decreased expression of PRKN protein CTD PMID:32434049 doxorubicin multiple interactions ISO Prkn (Mus musculus) 6480464 PRKN protein affects the reaction [Doxorubicin results in increased expression of MYH7 mRNA] and PRKN protein affects the reaction [Doxorubicin results in increased expression of NPPB mRNA] CTD PMID:32434049 doxorubicin multiple interactions EXP 6480464 Doxorubicin inhibits the reaction [YAP1 protein binds to PRKN promoter] CTD PMID:32434049 emtricitabine multiple interactions ISO PRKN (Homo sapiens) 6480464 [Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein CTD PMID:31545371 emtricitabine decreases expression ISO PRKN (Homo sapiens) 6480464 Emtricitabine results in decreased expression of PRKN protein CTD PMID:31545371 enzacamene multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA and [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA CTD PMID:25607892 epoxiconazole multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 epoxomicin multiple interactions EXP 6480464 epoxomicin inhibits the reaction [PRKN protein results in decreased susceptibility to Ceramides] CTD PMID:12588799 epoxomicin decreases expression EXP 6480464 epoxomicin results in decreased expression of PRKN mRNA CTD PMID:18586549 epoxomicin decreases expression ISO PRKN (Homo sapiens) 6480464 epoxomicin results in decreased expression of PRKN mRNA CTD PMID:18586549 ethanol decreases expression ISO Prkn (Mus musculus) 6480464 Ethanol results in decreased expression of PRKN protein CTD PMID:25460735 ethanol multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN protein inhibits the reaction [Ethanol results in decreased expression of FTH1 protein] more ... CTD PMID:35595033 ethanol decreases expression ISO PRKN (Homo sapiens) 6480464 Ethanol results in decreased expression of PRKN mRNA and Ethanol results in decreased expression of PRKN protein CTD PMID:35595033 ethanol affects expression ISO Prkn (Mus musculus) 6480464 Ethanol affects the expression of PRKN mRNA CTD PMID:30319688 fenpyroximate decreases expression ISO PRKN (Homo sapiens) 6480464 fenpyroximate results in decreased expression of PRKN mRNA CTD PMID:33512557 folic acid increases expression ISO Prkn (Mus musculus) 6480464 Folic Acid results in increased expression of PRKN mRNA and Folic Acid results in increased expression of PRKN protein CTD PMID:26547318 fulvestrant multiple interactions ISO PRKN (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRKN gene CTD PMID:31601247 furan increases methylation EXP 6480464 furan results in increased methylation of PRKN gene CTD PMID:22079235 furosemide multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 Genipin multiple interactions ISO Prkn (Mus musculus) 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein] and sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein]] CTD PMID:28477916 glucose multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 glucose decreases expression EXP 6480464 Glucose results in decreased expression of PRKN protein CTD PMID:35243728 glutathione affects abundance ISO Prkn (Mus musculus) 6480464 PRKN protein affects the abundance of Glutathione CTD PMID:12915482 Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of PRKN protein] and SIRT3 protein affects the reaction [honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of PRKN protein]] CTD PMID:34752757 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of PRKN mRNA and Hydrogen Peroxide results in increased expression of PRKN protein CTD PMID:25787151 hydrogen peroxide multiple interactions ISO Prkn (Mus musculus) 6480464 PRKN gene mutant form inhibits the reaction [Hydrogen Peroxide affects the localization of PARK7 protein] CTD PMID:22872702 hydrogen peroxide affects localization ISO Prkn (Mus musculus) 6480464 Hydrogen Peroxide affects the localization of PRKN protein CTD PMID:22872702 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of PRKN mRNA CTD PMID:21396975 indometacin multiple interactions ISO Prkn (Mus musculus) 6480464 Indomethacin promotes the reaction [PRKN gene mutant form results in increased susceptibility to Rotenone] CTD PMID:16573651 inositol multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 iodixanol multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 ketoconazole increases response to substance EXP 6480464 PRKN protein results in increased susceptibility to Ketoconazole CTD PMID:25787151 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of PRKN mRNA and Ketoconazole results in increased expression of PRKN protein CTD PMID:25787151 ketoconazole multiple interactions EXP 6480464 1 more ... CTD PMID:25787151 Lasiocarpine decreases expression ISO PRKN (Homo sapiens) 6480464 lasiocarpine results in decreased expression of PARK2 mRNA and lasiocarpine results in decreased expression of PRKN mRNA CTD PMID:32234424 and PMID:35690182 lead diacetate multiple interactions ISO Prkn (Mus musculus) 6480464 lead acetate results in increased phosphorylation of and affects the localization of PRKN protein CTD PMID:29660402 lead diacetate multiple interactions ISO PRKN (Homo sapiens) 6480464 [[amyloid beta-protein (25-35) co-treated with amyloid beta-protein (1-40)] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of PRKN protein more ... CTD PMID:35300571 lead diacetate affects localization ISO PRKN (Homo sapiens) 6480464 lead acetate affects the localization of PRKN protein CTD PMID:29660402 lead(0) multiple interactions ISO PRKN (Homo sapiens) 6480464 [[amyloid beta-protein (25-35) co-treated with amyloid beta-protein (1-40)] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of PRKN protein more ... CTD PMID:35300571 lead(0) multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Lead results in increased expression of PRKN mRNA] CTD PMID:34816377 lead(0) increases expression EXP 6480464 Lead results in increased expression of PRKN mRNA CTD PMID:34816377 linsidomine increases expression ISO PRKN (Homo sapiens) 6480464 linsidomine results in increased expression of PRKN protein CTD PMID:12880480 linsidomine multiple interactions ISO PRKN (Homo sapiens) 6480464 Selegiline inhibits the reaction [linsidomine results in increased expression of PRKN protein] CTD PMID:12880480 linuron multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 lipoic acid multiple interactions ISO Prkn (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Sodium Fluoride results in increased expression of PRKN mRNA] CTD PMID:37739047 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of PRKN protein CTD PMID:30084861 luteolin multiple interactions ISO Prkn (Mus musculus) 6480464 [Rotenone co-treated with Luteolin] results in increased expression of PRKN mRNA and Luteolin inhibits the reaction [Rotenone results in decreased expression of PRKN mRNA] CTD PMID:30207190 lycopene multiple interactions ISO Prkn (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN mRNA] and Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN protein] CTD PMID:36583613 maneb multiple interactions ISO Prkn (Mus musculus) 6480464 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein] more ... CTD PMID:22563483 and PMID:23985028 manganese atom decreases expression EXP 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:19781568 manganese atom decreases expression ISO PRKN (Homo sapiens) 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:28826884 manganese atom increases expression EXP 6480464 Manganese results in increased expression of PRKN protein CTD PMID:20798247 manganese atom affects response to substance ISO PRKN (Homo sapiens) 6480464 PRKN gene mutant form affects the susceptibility to Manganese CTD PMID:22841634 manganese atom decreases transport ISO PRKN (Homo sapiens) 6480464 PRKN protein results in decreased transport of Manganese CTD PMID:20089134 manganese(0) decreases expression EXP 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:19781568 manganese(0) decreases expression ISO PRKN (Homo sapiens) 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:28826884 manganese(0) increases expression EXP 6480464 Manganese results in increased expression of PRKN protein CTD PMID:20798247 manganese(0) affects response to substance ISO PRKN (Homo sapiens) 6480464 PRKN gene mutant form affects the susceptibility to Manganese CTD PMID:22841634 manganese(0) decreases transport ISO PRKN (Homo sapiens) 6480464 PRKN protein results in decreased transport of Manganese CTD PMID:20089134 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of PRKN protein CTD PMID:20798247 manganese(II) chloride decreases expression ISO PRKN (Homo sapiens) 6480464 manganese chloride results in decreased expression of PRKN mRNA CTD PMID:27913844 manganese(II) chloride increases methylation ISO PRKN (Homo sapiens) 6480464 manganese chloride results in increased methylation of PRKN gene CTD PMID:27913844 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of PRKN mRNA CTD PMID:20635692 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRKN protein] CTD PMID:26882442 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of PRKN protein CTD PMID:28661099 and PMID:31059759 methamphetamine multiple interactions EXP 6480464 CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein] CTD PMID:31059759 methamphetamine multiple interactions ISO PRKN (Homo sapiens) 6480464 CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein] more ... CTD PMID:31059759 methamphetamine decreases expression ISO PRKN (Homo sapiens) 6480464 Methamphetamine results in decreased expression of PRKN protein CTD PMID:31059759 methapyrilene increases methylation ISO PRKN (Homo sapiens) 6480464 Methapyrilene results in increased methylation of PRKN intron CTD PMID:30157460 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of PRKN gene CTD PMID:35440735 methylmercury chloride increases expression ISO Prkn (Mus musculus) 6480464 methylmercuric chloride results in increased expression of PRKN mRNA CTD PMID:20061341 miconazole increases expression EXP 6480464 Miconazole results in increased expression of PRKN mRNA CTD PMID:22262564 minocycline multiple interactions ISO Prkn (Mus musculus) 6480464 Minocycline inhibits the reaction [PRKN gene mutant form results in increased susceptibility to Rotenone] CTD PMID:16573651 N-acetyl-L-cysteine multiple interactions ISO Prkn (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA] more ... CTD PMID:22872702 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PRKN mRNA] and Acetylcysteine inhibits the reaction [Lead results in increased expression of PRKN mRNA] CTD PMID:34816377 N-acetyl-L-cysteine multiple interactions ISO PRKN (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [quinone results in increased expression of PRKN protein] CTD PMID:29567065 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO PRKN (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein] more ... CTD PMID:20089134 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal affects expression ISO PRKN (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of PRKN protein alternative form CTD PMID:28688199 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO PRKN (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN protein CTD PMID:28688199 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN mRNA CTD PMID:18586549 N-methyl-4-phenylpyridinium increases expression ISO PRKN (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PRKN mRNA CTD PMID:16987221 N-methyl-4-phenylpyridinium decreases expression ISO PRKN (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PRKN protein CTD PMID:28688199 N-methyl-4-phenylpyridinium affects expression ISO PRKN (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium affects the expression of PRKN protein alternative form CTD PMID:28688199 N-methyl-4-phenylpyridinium multiple interactions ISO PRKN (Homo sapiens) 6480464 Tretinoin affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of PRKN protein alternative form] CTD PMID:28688199 N-methyl-4-phenylpyridinium affects localization ISO Prkn (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium affects the localization of PRKN protein CTD PMID:22872702 N-methyl-4-phenylpyridinium increases expression ISO Prkn (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PRKN mRNA CTD PMID:26558463 N-Nitrosopyrrolidine decreases expression ISO PRKN (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of PARK2 mRNA and N-Nitrosopyrrolidine results in decreased expression of PRKN mRNA CTD PMID:32234424 and PMID:35690182 nickel atom multiple interactions ISO Prkn (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which affects the expression of and affects the localization of PRKN protein CTD PMID:36794572 nickel dichloride multiple interactions ISO Prkn (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which affects the expression of and affects the localization of PRKN protein CTD PMID:36794572 nicotine decreases expression ISO PRKN (Homo sapiens) 6480464 Nicotine results in decreased expression of PRKN mRNA CTD PMID:16949557 O-acetyl-L-carnitine multiple interactions ISO Prkn (Mus musculus) 6480464 Acetylcarnitine inhibits the reaction [Cadmium results in increased expression of PRKN] CTD PMID:25464205 O-methyleugenol decreases expression ISO PRKN (Homo sapiens) 6480464 methyleugenol results in decreased expression of PARK2 mRNA and methyleugenol results in decreased expression of PRKN mRNA CTD PMID:32234424 and PMID:35690182 oligomycin A multiple interactions ISO PRKN (Homo sapiens) 6480464 [oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein and PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein] CTD PMID:28366621 oxidopamine decreases reaction ISO PRKN (Homo sapiens) 6480464 PRKN protein inhibits the reaction Oxidopamine CTD PMID:15198987 oxidopamine affects expression ISO PRKN (Homo sapiens) 6480464 Oxidopamine affects the expression of PRKN protein alternative form CTD PMID:28688199 oxidopamine decreases expression ISO PRKN (Homo sapiens) 6480464 Oxidopamine results in decreased expression of PRKN protein CTD PMID:28688199 and PMID:30707903 oxidopamine multiple interactions ISO PRKN (Homo sapiens) 6480464 PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]] more ... CTD PMID:28688199 and PMID:30707903 oxidopamine multiple interactions ISO Prkn (Mus musculus) 6480464 PRKN protein inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:16914382 oxidopamine multiple interactions EXP 6480464 isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] more ... CTD PMID:25129099 oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of PRKN mRNA CTD PMID:25129099 ozone multiple interactions ISO Prkn (Mus musculus) 6480464 3-(4-t-butylphenyl)-N-(2 more ... CTD PMID:35928613 ozone increases expression ISO Prkn (Mus musculus) 6480464 Ozone results in increased expression of PRKN protein CTD PMID:35928613 paracetamol multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA CTD PMID:25607892 paracetamol decreases expression ISO Prkn (Mus musculus) 6480464 Acetaminophen results in decreased expression of PRKN mRNA CTD PMID:37179516 paracetamol multiple interactions ISO Prkn (Mus musculus) 6480464 [Acetaminophen co-treated with PRKN gene mutant form] results in decreased phosphorylation of GYS1 protein more ... CTD PMID:25752611 and PMID:33271250 paracetamol affects localization ISO Prkn (Mus musculus) 6480464 Acetaminophen affects the localization of PRKN protein CTD PMID:25752611 paracetamol decreases response to substance ISO Prkn (Mus musculus) 6480464 PRKN gene mutant form results in decreased susceptibility to Acetaminophen CTD PMID:25752611 paracetamol increases expression ISO Prkn (Mus musculus) 6480464 Acetaminophen results in increased expression of PRKN protein CTD PMID:33271250 and PMID:37179516 paraquat multiple interactions ISO Prkn (Mus musculus) 6480464 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein] more ... CTD PMID:22563483 more ... paraquat increases expression ISO Prkn (Mus musculus) 6480464 Paraquat results in increased expression of PRKN mRNA CTD PMID:31368586 paraquat decreases expression ISO PRKN (Homo sapiens) 6480464 Paraquat results in decreased expression of PRKN mRNA CTD PMID:34097952 paraquat increases phosphorylation ISO PRKN (Homo sapiens) 6480464 Paraquat results in increased phosphorylation of PRKN protein CTD PMID:33383311 paraquat multiple interactions ISO PRKN (Homo sapiens) 6480464 Antigens more ... CTD PMID:30144575 more ... paraquat decreases expression ISO Prkn (Mus musculus) 6480464 Paraquat results in decreased expression of PRKN mRNA CTD PMID:22563483 perfluorooctane-1-sulfonic acid multiple interactions ISO Prkn (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRKN mRNA CTD PMID:36331819 picoxystrobin decreases expression ISO PRKN (Homo sapiens) 6480464 picoxystrobin results in decreased expression of PRKN mRNA CTD PMID:33512557 poly(vinylpyrrolidone) multiple interactions ISO Prkn (Mus musculus) 6480464 [Silver Compounds co-treated with Povidone] results in increased expression of PRKN protein CTD PMID:35697184 prochloraz multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 procymidone multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 pyrimidifen decreases expression ISO PRKN (Homo sapiens) 6480464 pyrimidifen results in decreased expression of PRKN mRNA CTD PMID:33512557 quercetin 3-O-beta-D-glucofuranoside multiple interactions EXP 6480464 isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 quercetin 3-O-beta-D-glucopyranoside multiple interactions EXP 6480464 isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 reactive oxygen species decreases abundance ISO PRKN (Homo sapiens) 6480464 PRKN protein results in decreased abundance of Reactive Oxygen Species CTD PMID:15198987 and PMID:31926197 reactive oxygen species multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN protein inhibits the reaction [Dopamine results in increased abundance of Reactive Oxygen Species] CTD PMID:15198987 resveratrol multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN gene mutant form affects the reaction [resveratrol results in increased expression of COX1 mRNA] more ... CTD PMID:24582596 resveratrol multiple interactions EXP 6480464 [Resveratrol co-treated with Benzo(a)pyrene] results in increased expression of PRKN protein CTD PMID:32619457 resveratrol increases expression EXP 6480464 Resveratrol results in increased expression of PRKN protein CTD PMID:32619457 rimonabant decreases response to substance ISO Prkn (Mus musculus) 6480464 PRKN results in decreased susceptibility to Rimonabant CTD PMID:15882845 rimonabant multiple interactions EXP 6480464 Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein] CTD PMID:15882845 rotenone multiple interactions ISO PRKN (Homo sapiens) 6480464 4 more ... CTD PMID:19741132 more ... rotenone increases expression ISO PRKN (Homo sapiens) 6480464 Rotenone results in increased expression of PRKN protein CTD PMID:37156403 rotenone multiple interactions EXP 6480464 [Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein more ... CTD PMID:33823232 and PMID:35104487 rotenone decreases expression ISO Prkn (Mus musculus) 6480464 Rotenone results in decreased expression of PRKN mRNA CTD PMID:30207190 rotenone affects expression EXP 6480464 Rotenone affects the expression of PRKN mRNA CTD PMID:31814881 rotenone affects localization ISO PRKN (Homo sapiens) 6480464 Rotenone affects the localization of PRKN protein CTD PMID:32001317 rotenone decreases expression ISO PRKN (Homo sapiens) 6480464 Rotenone results in decreased expression of PRKN mRNA and Rotenone results in decreased expression of PRKN protein CTD PMID:31926197 more ... rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PRKN mRNA and Rotenone results in decreased expression of PRKN protein CTD PMID:32392329 and PMID:35104487 rotenone decreases response to substance ISO Prkn (Mus musculus) 6480464 PRKN protein results in decreased susceptibility to Rotenone CTD PMID:16517603 rotenone increases response to substance ISO Prkn (Mus musculus) 6480464 PRKN gene mutant form results in increased susceptibility to Rotenone CTD PMID:16517603 and PMID:16573651 rotenone multiple interactions ISO Prkn (Mus musculus) 6480464 [Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein more ... CTD PMID:16573651 more ... rotenone affects localization ISO Prkn (Mus musculus) 6480464 Rotenone affects the localization of PRKN protein CTD PMID:22872702 rotenone affects response to substance ISO PRKN (Homo sapiens) 6480464 PRKN protein affects the susceptibility to Rotenone CTD PMID:20940149 rotenone decreases response to substance ISO PRKN (Homo sapiens) 6480464 PRKN protein results in decreased susceptibility to Rotenone CTD PMID:17687034 and PMID:19741132 rotenone increases response to substance ISO PRKN (Homo sapiens) 6480464 PRKN gene mutant form results in increased susceptibility to Rotenone CTD PMID:17687034 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 S-nitrosoglutathione multiple interactions ISO PRKN (Homo sapiens) 6480464 [S-Nitrosoglutathione results in increased nitrosation of PRKN protein] inhibits the reaction [PRKN protein binds to TP53 promoter] more ... CTD PMID:23985028 silibinin multiple interactions ISO PRKN (Homo sapiens) 6480464 Silybin inhibits the reaction [Acetaldehyde results in decreased expression of PRKN mRNA] more ... CTD PMID:35595033 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of PRKN protein CTD PMID:27613482 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein] CTD PMID:33823232 sirolimus multiple interactions ISO Prkn (Mus musculus) 6480464 Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein] and Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of PRKN protein] CTD PMID:33823232 and PMID:35405287 sirtinol multiple interactions ISO Prkn (Mus musculus) 6480464 sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein]] CTD PMID:28477916 sodium arsenite affects methylation ISO PRKN (Homo sapiens) 6480464 sodium arsenite affects the methylation of PRKN gene CTD PMID:28589171 sodium arsenite increases expression ISO Prkn (Mus musculus) 6480464 sodium arsenite results in increased expression of PRKN mRNA and sodium arsenite results in increased expression of PRKN protein CTD PMID:36557995 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PRKN protein CTD PMID:30551535 sodium fluoride increases expression ISO Prkn (Mus musculus) 6480464 Sodium Fluoride results in increased expression of PRKN mRNA CTD PMID:37739047 sodium fluoride multiple interactions ISO Prkn (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Sodium Fluoride results in increased expression of PRKN mRNA] CTD PMID:37739047 sorafenib multiple interactions ISO PRKN (Homo sapiens) 6480464 [sorafenib co-treated with PRKN protein] results in decreased expression of CASP3 protein more ... CTD PMID:28673964 sorafenib affects response to substance ISO Prkn (Mus musculus) 6480464 PRKN protein affects the susceptibility to sorafenib CTD PMID:28673964 sorafenib increases ubiquitination ISO Prkn (Mus musculus) 6480464 sorafenib results in increased ubiquitination of PRKN protein CTD PMID:28673964 sorafenib increases ubiquitination ISO PRKN (Homo sapiens) 6480464 sorafenib results in increased ubiquitination of PRKN protein CTD PMID:28673964 sorafenib affects localization ISO PRKN (Homo sapiens) 6480464 sorafenib affects the localization of PRKN protein CTD PMID:28673964 sunitinib increases expression ISO PRKN (Homo sapiens) 6480464 Sunitinib results in increased expression of PRKN mRNA CTD PMID:31533062 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of PRKN mRNA and T-2 Toxin results in increased expression of PRKN protein CTD PMID:29870751 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PRKN protein] CTD PMID:30551535 tebufenpyrad decreases expression ISO PRKN (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of PRKN mRNA CTD PMID:33512557 tenofovir disoproxil fumarate multiple interactions ISO PRKN (Homo sapiens) 6480464 [Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein CTD PMID:31545371 tetrachloromethane multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRKN protein] CTD PMID:26882442 tetrachloromethane increases expression ISO Prkn (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of PRKN protein CTD PMID:35405287 tetrachloromethane multiple interactions ISO Prkn (Mus musculus) 6480464 Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of PRKN protein] CTD PMID:35405287 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of PRKN protein CTD PMID:26882442 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PRKN mRNA CTD PMID:23411599 Tiron multiple interactions EXP 6480464 1 more ... CTD PMID:25787151 Tiron multiple interactions ISO Prkn (Mus musculus) 6480464 1 more ... CTD PMID:22872702 titanium dioxide increases expression ISO PRKN (Homo sapiens) 6480464 titanium dioxide results in increased expression of PRKN mRNA CTD PMID:30273564 trans-piceid multiple interactions ISO PRKN (Homo sapiens) 6480464 [PRKN protein affects the susceptibility to polydatin] which results in increased expression of PARK7 protein CTD PMID:31926197 trans-piceid affects response to substance ISO PRKN (Homo sapiens) 6480464 PRKN protein affects the susceptibility to polydatin CTD PMID:31926197 trifloxystrobin increases expression ISO PRKN (Homo sapiens) 6480464 trifloxystrobin results in increased expression of PRKN protein CTD PMID:27853101 trifloxystrobin multiple interactions ISO PRKN (Homo sapiens) 6480464 MitoTEMPO inhibits the reaction [trifloxystrobin results in increased expression of PRKN protein] CTD PMID:27853101 trifluoperazine affects localization ISO PRKN (Homo sapiens) 6480464 Trifluoperazine affects the localization of PRKN protein CTD PMID:28366621 trifluoperazine multiple interactions ISO PRKN (Homo sapiens) 6480464 PRKN protein affects the reaction [Trifluoperazine affects the localization of PRKN protein] CTD PMID:28366621 trimellitic anhydride decreases expression ISO Prkn (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of PRKN mRNA CTD PMID:19042947 tubocurarine decreases expression ISO PRKN (Homo sapiens) 6480464 Tubocurarine results in decreased expression of PRKN mRNA CTD PMID:16949557 valproic acid decreases methylation ISO PRKN (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of PRKN gene CTD PMID:29154799 valproic acid increases expression ISO PRKN (Homo sapiens) 6480464 Valproic Acid results in increased expression of PRKN mRNA CTD PMID:37505509 venlafaxine hydrochloride multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein]] and Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein] CTD PMID:35104487 vinclozolin multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892