Gene: Timp2 (TIMP metallopeptidase inhibitor 2) Rattus norvegicus
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Symbol: Timp2
Name: TIMP metallopeptidase inhibitor 2
Description: ENCODES a protein that exhibits integrin binding; metalloendopeptidase inhibitor activity; enzyme activator activity (ortholog); INVOLVED IN aging; central nervous system development; negative regulation of cell proliferation; ASSOCIATED WITH Acute Lung Injury; Brain Injuries; Cardiomyopathies; FOUND IN cell surface; extracellular space; growth cone; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: metalloproteinase inhibitor 2; MGC105282; TIMP-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinases 2
Orthologs:
Homo sapiens (human) : TIMP2 (TIMP metallopeptidase inhibitor 2)  HGNC  AGR
Mus musculus (house mouse) : Timp2 (tissue inhibitor of metalloproteinase 2)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Timp2 (TIMP metallopeptidase inhibitor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TIMP2 (TIMP metallopeptidase inhibitor 2)
Canis lupus familiaris (dog) : TIMP2 (TIMP metallopeptidase inhibitor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Timp2 (TIMP metallopeptidase inhibitor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010107,338,465 - 107,386,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010106,973,463 - 107,021,070 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,310,473 - 108,358,821 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110108,324,976 - 108,373,325 (-)NCBI
Celera10102,103,187 - 102,150,797 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Timp2
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61312
Created: 2001-01-05
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE