Gene: Zap70 (zeta chain of T cell receptor associated protein kinase 70) Rattus norvegicus
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Symbol: Zap70
Name: zeta chain of T cell receptor associated protein kinase 70
Description: ENCODES a protein that exhibits ATP binding (ortholog); phosphotyrosine residue binding (ortholog); protein kinase activity (ortholog); INVOLVED IN beta selection (ortholog); immune response (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; primary immunodeficiency disease pathway; T cell receptor signaling pathway; ASSOCIATED WITH artemis deficiency (ortholog); AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2 (ortholog); B cell deficiency (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 2,3,4,7,8-Pentachlorodibenzofuran
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC108902; Srk; syk-related protein tyrosine kinase; tyrosine-protein kinase ZAP-70; Zap70_mapped; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70 (mapped); zeta-chain (TCR) associated protein kinase 70kDa
Orthologs:
Homo sapiens (human) : ZAP70 (zeta chain of T-cell receptor associated protein kinase 70)  HGNC  AGR
Mus musculus (house mouse) : Zap70 (zeta-chain (TCR) associated protein kinase)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Zap70 (zeta-chain (TCR) associated protein kinase 70kDa)
Pan paniscus (bonobo/pygmy chimpanzee) : ZAP70 (zeta-chain (TCR) associated protein kinase 70kDa)
Canis lupus familiaris (dog) : ZAP70 (tyrosine-protein kinase ZAP-70)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101971458 (tyrosine-protein kinase ZAP-70)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0943,331,149 - 43,353,097 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0942,980,050 - 43,002,015 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4935,693,089 - 35,715,071 (+)NCBIRGSC3.4rn4RGSC3.4
Celera936,755,106 - 36,777,088 (+)NCBI
Cytogenetic Map9q21NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Zap70
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 3983
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE