Gene: Abcc8 (ATP binding cassette subfamily C member 8) Rattus norvegicus
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Symbol: Abcc8
Name: ATP binding cassette subfamily C member 8
Description: ENCODES a protein that exhibits ATP binding; potassium channel activity; syntaxin binding; INVOLVED IN cellular glucose homeostasis; cellular response to organic substance; female pregnancy; PARTICIPATES IN diabetes pathway; acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; ASSOCIATED WITH autosomal recessive juvenile Parkinson disease 2; Brain Edema; brain edema; FOUND IN ATP-sensitive potassium channel complex; mitochondrion; sarcolemma; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C (CFTR/MRP) member 8; ATP-binding cassette sub-family C member 8; ATP-binding cassette subfamily C (CFTR/MRP) member 8; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; ATP-binding cassette, subfamily C (CFTR/MRP), member 8; sulfonylurea receptor; sulfonylurea receptor 1; sulphonylurea receptor 1; Sur; Sur1
Orthologs:
Homo sapiens (human) : ABCC8 (ATP binding cassette subfamily C member 8)  HGNC
Mus musculus (house mouse) : Abcc8 (ATP-binding cassette, sub-family C (CFTR/MRP), member 8)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Abcc8 (ATP binding cassette subfamily C member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCC8 (ATP binding cassette subfamily C member 8)
Canis lupus familiaris (dog) : ABCC8 (ATP binding cassette subfamily C member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc8 (ATP binding cassette subfamily C member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01102,110,708 - 102,191,287 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01103,194,473 - 103,275,508 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4196,622,574 - 96,703,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,700,590 - 96,781,880 (-)NCBI
Celera190,849,685 - 90,928,224 (-)NCBI
Cytogenetic Map1q22NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abcc8
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RGD Object Information
RGD ID: 3786
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-08-08
Status: ACTIVE