Gene: Abcc8 (ATP-binding cassette, subfamily C (CFTR/MRP), member 8) Rattus norvegicus
Symbol: Abcc8
Name: ATP-binding cassette, subfamily C (CFTR/MRP), member 8
Description: ENCODES a protein that exhibits ATP binding; potassium channel activity; syntaxin binding; INVOLVED IN cellular response to organic substance; negative regulation of insulin secretion; positive regulation of potassium ion transport; PARTICIPATES IN diabetes pathway; altered insulin secretion pathway; forkhead class A signaling pathway; ASSOCIATED WITH increased circulating insulin level; ASSOCIATED WITH Brain Edema; Endotoxemia; Hyperinsulinism; FOUND IN sarcolemma; synaptic vesicle membrane; plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C (CFTR/MRP) member 8; ATP-binding cassette sub-family C member 8; ATP-binding cassette subfamily C (CFTR/MRP) member 8; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; sulfonylurea receptor; sulfonylurea receptor 1; sulphonylurea receptor 1; Sur; Sur1
Orthologs:
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.01102,110,436 - 102,191,359-NCBI
Rat Cytogenetic Map1q22 NCBI
RGSC Genome Assembly v5.01103,194,473 - 103,275,508-NCBI
RGSC Genome Assembly v3.4196,622,574 - 96,703,723-NCBI
Rat Celera Assembly190,849,685 - 90,928,224-NCBI
Genome Assembly 3.1196,700,590 - 96,781,880-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abcc8
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Ensembl Gene
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RGD Object Information
RGD ID: 3786
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-11-11
Status: ACTIVE