Pygb (glycogen phosphorylase B) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pygb (glycogen phosphorylase B) Rattus norvegicus
Analyze
Symbol: Pygb
Name: glycogen phosphorylase B
RGD ID: 3460
Description: Enables several functions, including carbohydrate binding activity; glycogen phosphorylase activity; and identical protein binding activity. Involved in glycogen catabolic process. Located in axon. Orthologous to human PYGB (glycogen phosphorylase B); PARTICIPATES IN glycogen degradation pathway; insulin signaling pathway; starch and sucrose metabolic pathway; INTERACTS WITH 2,5-hexanedione; 3-chloropropane-1,2-diol; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain; brain glycogen phosphorylase; glycogen phosphorylase, brain form; GLYPHOA; phosphorylase, glycogen; phosphorylase, glycogen; brain
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83160,072,141 - 160,118,930 (+)NCBIGRCr8
mRatBN7.23139,611,724 - 139,658,521 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3139,611,749 - 139,663,553 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,507,801 - 143,554,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03152,091,537 - 152,138,438 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03149,840,091 - 149,886,995 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03146,581,063 - 146,629,504 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,582,752 - 146,634,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03152,941,739 - 152,988,417 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,421,421 - 141,468,094 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,327,094 - 141,373,658 (+)NCBI
Celera3138,373,554 - 138,420,266 (+)NCBICelera
RH 3.4 Map31196.32RGD
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,5-hexanedione  (EXP)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
Aflatoxin B2 alpha  (ISO)
alvocidib  (ISO)
ammonium chloride  (EXP)
baicalein  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
cadmium dichloride  (EXP)
calcidiol  (EXP)
cantharidin  (ISO)
capecitabine  (ISO)
CGP 52608  (ISO)
choline  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dichlorvos  (EXP)
diethyldithiocarbamic acid  (EXP)
dioxygen  (ISO)
diuron  (EXP)
doxifluridine  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
hydroquinone  (ISO)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP)
methapyrilene  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
paracetamol  (EXP)
PCB138  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
plumbagin  (EXP)
quercetin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium nitrate  (ISO)
Soman  (EXP)
sotorasib  (ISO)
sulforaphane  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
toxaphene  (EXP)
trametinib  (ISO)
trimellitic anhydride  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IDA)
cytoplasm  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors. Birch AM, etal., Bioorg Med Chem Lett. 2007 Jan 15;17(2):394-9. Epub 2006 Oct 19.
2. Structural relationships among regulated and unregulated phosphorylases. Buchbinder JL, etal., Annu Rev Biophys Biomol Struct. 2001;30:191-209.
3. Studies on the expression and evolution of the glycogen phosphorylase gene family in the rat. Crerar MM, etal., Genome 1988 Aug;30(4):582-90.
4. Idazoxan activates rat forebrain glycogen phosphorylase in vivo: a histochemical study. Fara-On M, etal., Brain Res. 2005 Oct 12;1059(1):83-92. Epub 2005 Oct 13.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Comparative analysis of species-independent, isozyme-specific amino-acid substitutions in mammalian muscle, brain and liver glycogen phosphorylases. Hudson JW, etal., Biochim Biophys Acta 1993 Jul 10;1164(2):197-208.
8. Glycogen phosphorylase: control by phosphorylation and allosteric effectors. Johnson LN FASEB J. 1992 Mar;6(6):2274-82.
9. Histochemical mapping of the substrate for brain-stimulation reward with glycogen phosphorylase. Konkle AT, etal., J Neurosci Methods. 1999 Nov 15;93(2):111-9.
10. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
11. Glycogen synthesis in the astrocyte: from glycogenin to proglycogen to glycogen. Lomako J, etal., FASEB J. 1993 Nov;7(14):1386-93.
12. Glycogen phosphorylase isoenzymes from hepatoma 3924A and from a non-tumorigenic liver cell line. Comparison with the liver and brain enzymes. Mayer D, etal., Biochem J. 1992 Mar 15;282 ( Pt 3):665-73.
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. Glycogen phosphorylase isozymes and energy metabolism in the rat peripheral nervous system--an immunocytochemical study. Pfeiffer-Guglielmi B, etal., Brain Res. 2007 Mar 9;1136(1):20-7. Epub 2006 Dec 20.
15. Isozyme pattern of glycogen phosphorylase in the rat nervous system and rat astroglia-rich primary cultures: electrophoretic and polymerase chain reaction studies. Pfeiffer-Guglielmi B, etal., Neurochem Res. 2000 Nov;25(11):1485-91.
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10638593   PMID:12477932   PMID:16229987   PMID:16879805   PMID:17442042   PMID:19292454   PMID:19946888   PMID:21700703   PMID:22206666   PMID:22871113   PMID:23533145  
PMID:25931508   PMID:26316108   PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Pygb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83160,072,141 - 160,118,930 (+)NCBIGRCr8
mRatBN7.23139,611,724 - 139,658,521 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3139,611,749 - 139,663,553 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,507,801 - 143,554,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03152,091,537 - 152,138,438 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03149,840,091 - 149,886,995 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03146,581,063 - 146,629,504 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,582,752 - 146,634,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03152,941,739 - 152,988,417 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,421,421 - 141,468,094 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,327,094 - 141,373,658 (+)NCBI
Celera3138,373,554 - 138,420,266 (+)NCBICelera
RH 3.4 Map31196.32RGD
Cytogenetic Map3q41NCBI
PYGB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382025,248,085 - 25,298,012 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2025,248,085 - 25,298,012 (+)EnsemblGRCh38hg38GRCh38
GRCh372025,228,721 - 25,278,648 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362025,176,706 - 25,226,648 (+)NCBINCBI36Build 36hg18NCBI36
Build 342025,176,705 - 25,226,648NCBI
Celera2025,302,440 - 25,352,386 (+)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2025,186,079 - 25,235,994 (+)NCBIHuRef
CHM1_12025,229,585 - 25,279,528 (+)NCBICHM1_1
T2T-CHM13v2.02025,313,131 - 25,363,101 (+)NCBIT2T-CHM13v2.0
Pygb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392150,628,716 - 150,673,668 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2150,628,655 - 150,673,678 (+)EnsemblGRCm39 Ensembl
GRCm382150,786,796 - 150,831,748 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2150,786,735 - 150,831,758 (+)EnsemblGRCm38mm10GRCm38
MGSCv372150,612,532 - 150,657,484 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362150,478,237 - 150,523,189 (+)NCBIMGSCv36mm8
Celera2152,019,819 - 152,065,130 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.74NCBI
Pygb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,254,204 - 31,283,651 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,254,240 - 31,283,651 (+)NCBIChiLan1.0ChiLan1.0
PYGB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22126,121,781 - 26,173,790 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12026,118,634 - 26,170,623 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02025,191,066 - 25,242,955 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12025,607,895 - 25,648,066 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2025,593,589 - 25,648,066 (+)Ensemblpanpan1.1panPan2
PYGB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1231,440,826 - 1,494,570 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl231,420,052 - 1,496,245 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,470,378 - 1,524,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0231,681,167 - 1,734,965 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl231,681,075 - 1,735,315 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1231,521,968 - 1,575,698 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0231,646,573 - 1,700,313 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0231,613,910 - 1,667,799 (+)NCBIUU_Cfam_GSD_1.0
Pygb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640147,113,119 - 147,155,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936620532,634 - 575,916 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936620533,574 - 575,893 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PYGB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,940,452 - 30,995,691 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,940,457 - 30,995,688 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103247035
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660787,750,872 - 7,807,853 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pygb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624939270,652 - 302,608 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624939273,448 - 302,604 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pygb
282 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:297
Count of miRNA genes:206
Interacting mature miRNAs:244
Transcripts:ENSRNOT00000010157
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat

Markers in Region
RH127518  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23139,658,253 - 139,658,442 (+)MAPPERmRatBN7.2
Rnor_6.03146,629,237 - 146,629,425NCBIRnor6.0
Rnor_5.03152,988,150 - 152,988,338UniSTSRnor5.0
RGSC_v3.43141,467,827 - 141,468,015UniSTSRGSC3.4
Celera3138,419,999 - 138,420,187UniSTS
RH 3.4 Map31192.91UniSTS
Cytogenetic Map3q41UniSTS
RH94711  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23139,657,832 - 139,657,942 (+)MAPPERmRatBN7.2
Rnor_6.03146,628,816 - 146,628,925NCBIRnor6.0
Rnor_5.03152,987,729 - 152,987,838UniSTSRnor5.0
RGSC_v3.43141,467,406 - 141,467,515UniSTSRGSC3.4
Celera3138,419,578 - 138,419,687UniSTS
RH 3.4 Map31196.32UniSTS
Cytogenetic Map3q41UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 22 6 19 6 74 35 34 11
Low 35 35 35 8 11 7 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000010157   ⟹   ENSRNOP00000010158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3139,611,768 - 139,663,552 (+)Ensembl
Rnor_6.0 Ensembl3146,582,752 - 146,634,535 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100727   ⟹   ENSRNOP00000084107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3139,611,760 - 139,658,175 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111537   ⟹   ENSRNOP00000093697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3139,611,749 - 139,663,553 (+)Ensembl
RefSeq Acc Id: NM_013188   ⟹   NP_037320
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83160,072,141 - 160,118,930 (+)NCBI
mRatBN7.23139,611,724 - 139,658,521 (+)NCBI
Rnor_6.03146,582,708 - 146,629,504 (+)NCBI
Rnor_5.03152,941,739 - 152,988,417 (+)NCBI
RGSC_v3.43141,421,421 - 141,468,094 (+)RGD
Celera3138,373,554 - 138,420,266 (+)RGD
Sequence:
RefSeq Acc Id: NP_037320   ⟸   NM_013188
- UniProtKB: P53534 (UniProtKB/Swiss-Prot),   A6KHG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010158   ⟸   ENSRNOT00000010157
RefSeq Acc Id: ENSRNOP00000084107   ⟸   ENSRNOT00000100727
RefSeq Acc Id: ENSRNOP00000093697   ⟸   ENSRNOT00000111537

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P53534-F1-model_v2 AlphaFold P53534 1-838 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692518
Promoter ID:EPDNEW_R3043
Type:initiation region
Name:Pygb_1
Description:glycogen phosphorylase B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03146,582,733 - 146,582,793EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3460 AgrOrtholog
BioCyc Gene G2FUF-47337 BioCyc
BioCyc Pathway PWY-5941 [glycogen degradation II] BioCyc
BioCyc Pathway Image PWY-5941 BioCyc
Ensembl Genes ENSRNOG00000007583 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010157.7 UniProtKB/TrEMBL
  ENSRNOT00000100727 ENTREZGENE
  ENSRNOT00000100727.1 UniProtKB/TrEMBL
  ENSRNOT00000111537.1 UniProtKB/TrEMBL
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9100353 IMAGE-MGC_LOAD
InterPro Glycg_phsphrylas UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_trans_35 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pyridoxal_P_attach_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25739 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:187917 IMAGE-MGC_LOAD
NCBI Gene 25739 ENTREZGENE
PANTHER GLYCOGEN PHOSPHORYLASE, BRAIN FORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11468 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Phosphorylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pygb PhenoGen
PIRSF Pprylas_GlgP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PHOSPHORYLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007583 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6G9W3_RAT UniProtKB/TrEMBL
  A0A8I6GKE5_RAT UniProtKB/TrEMBL
  A6KHG6 ENTREZGENE, UniProtKB/TrEMBL
  A6KHG7_RAT UniProtKB/TrEMBL
  G3V6Y6_RAT UniProtKB/TrEMBL
  P53534 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2GV03 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-11-18 Pygb  glycogen phosphorylase B  Pygb  phosphorylase, glycogen; brain  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-11 Pygb  phosphorylase, glycogen; brain  Pygb  brain glycogen phosphorylase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pygb  Brain glycogen phosphorylase      Symbol and Name status set to approved 70586 APPROVED