Pcca (propionyl-CoA carboxylase subunit alpha)

Gene: Pcca (propionyl-CoA carboxylase subunit alpha) Rattus norvegicus

Analyze

Symbol:

Pcca

Name:

propionyl-CoA carboxylase subunit alpha

RGD ID:

3264

Description:

Predicted to enable enzyme binding activity and propionyl-CoA carboxylase activity. Predicted to be involved in amino acid catabolic process and fatty acid catabolic process. Predicted to be located in mitochondrial matrix. Predicted to be part of catalytic complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Orthologous to human PCCA (propionyl-CoA carboxylase subunit alpha); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC687008; PCCase alpha subunit; PCCase subunit alpha; propanoyl-CoA:carbon dioxide ligase alpha subunit; propanoyl-CoA:carbon dioxide ligase subunit alpha; propionyl CoA carboxylase, alpha polypeptide; Propionyl Coenzyme A carboxylase alpha polypeptide; Propionyl Coenzyme A carboxylase, alpha polypeptide; propionyl-CoA carboxylase alpha chain, mitochondrial; propionyl-CoA carboxylase alpha subunit; propionyl-coenzyme A carboxylase, alpha polypeptide; similar to Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (PCCase alpha subunit) (Propanoyl-CoA:carbon dioxide ligase alpha subunit)

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	106,034,586 - 106,374,908 (+)	NCBI		GRCr8
mRatBN7.2	15	99,627,955 - 99,969,555 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	99,627,982 - 99,968,266 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	103,560,589 - 103,901,667 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	104,665,702 - 105,000,289 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	101,592,936 - 101,927,542 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	108,960,509 - 109,306,879 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	108,960,562 - 109,306,603 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	112,346,155 - 112,477,427 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	15	112,502,385 - 112,687,789 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	107,659,723 - 108,028,929 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	107,675,589 - 108,044,696 (+)	NCBI
Celera	15	98,401,724 - 98,738,731 (+)	NCBI		Celera
RH 3.4 Map	15	692.11	RGD
Cytogenetic Map	15	q25	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amino acid metabolic disorder (ISO)

Anal Atresia, Hypospadias, and Penoscrotal Inversion (ISO)

genetic disease (ISO)

holoprosencephaly (ISO)

holoprosencephaly 5 (ISO)

pontocerebellar hypoplasia type 2D (ISO)

propionic acidemia (ISO,ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,1-dichloroethene (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrabromodibenzodioxine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3-chloropropane-1,2-diol (EXP)

7,12-dimethyltetraphene (ISO)

aconitine (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

chlorpyrifos (ISO)

choline (ISO)

chromium trinitrate (ISO)

cisplatin (ISO)

clothianidin (ISO)

cobalt dichloride (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP,ISO)

dicrotophos (ISO)

diuron (EXP)

doxorubicin (ISO)

endosulfan (ISO)

flutamide (EXP)

folic acid (ISO)

fulvestrant (ISO)

gallic acid (ISO)

genistein (ISO)

glafenine (EXP)

gold atom (ISO)

gold(0) (ISO)

indometacin (EXP)

inulin (ISO)

ivermectin (ISO)

L-methionine (ISO)

menadione (ISO)

methapyrilene (EXP,ISO)

N-nitrosomorpholine (EXP)

O-methyleugenol (ISO)

oxaliplatin (EXP)

ozone (ISO)

paclitaxel (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

PhIP (EXP)

phlorizin (ISO)

pirinixic acid (EXP)

potassium chromate (ISO)

progesterone (EXP,ISO)

quercetin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP)

sodium dichromate (EXP)

temozolomide (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

topotecan (EXP)

tunicamycin (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amino acid catabolic process (TAS)

carboxylic acid metabolic process (IEA)

fatty acid catabolic process (TAS)

lipid catabolic process (IEA)

Cellular Component

catalytic complex (IEA,ISO)

mitochondrial matrix (IEA,ISO,ISS)

mitochondrion (IBA,IEA,ISO)

Molecular Function

ATP binding (IEA)

enzyme binding (IEA,ISO)

metal ion binding (IEA)

methylcrotonoyl-CoA carboxylase activity (IEA)

propionyl-CoA carboxylase activity (IBA,IEA,ISO,ISS,TAS)

protein binding (ISO)

urea carboxylase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway (ISO)

3-hydroxyisobutyric aciduria pathway (ISO)

3-methylcrotonyl CoA carboxylase 1 deficiency pathway (ISO)

3-methylglutaconic aciduria type 1 pathway (ISO)

3-methylglutaconic aciduria type 3 pathway (ISO)

glyoxylate and dicarboxylate metabolic pathway (IEA)

isobutyryl-CoA dehydrogenase deficiency pathway (ISO)

isovaleric acidemia pathway (ISO)

malonic aciduria pathway (ISO)

maple syrup urine disease pathway (ISO)

methylmalonate semialdehyde dehydrogenase deficiency pathway (ISO)

methylmalonic acidemia pathway (ISO)

methylmalonic aciduria, cobalamin-related pathway (ISO)

propanoate metabolic pathway (IEA,ISO)

propionic acidemia pathway (ISO)

valine, leucine and isoleucine degradation pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Sequence analysis, biogenesis, and mitochondrial import of the alpha-subunit of rat liver propionyl-CoA carboxylase.	Browner MF, etal., J Biol Chem 1989 Jul 25;264(21):12680-5.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
10.	GOA pipeline	RGD automated data pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Three novel splice mutations in the PCCA gene causing identical exon skipping in propionic acidemia patients.	Richard E, etal., Hum Genet. 1997 Nov;101(1):93-6.
14.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:6765947	PMID:8434582	PMID:8889548	PMID:11461925	PMID:13752080	PMID:14651853	PMID:15060005	PMID:16023992	PMID:18614015	PMID:19157941	PMID:19699272	PMID:26316108
PMID:31505169

Genomics

Comparative Map Data

Pcca
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	106,034,586 - 106,374,908 (+)	NCBI		GRCr8
mRatBN7.2	15	99,627,955 - 99,969,555 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	99,627,982 - 99,968,266 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	103,560,589 - 103,901,667 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	104,665,702 - 105,000,289 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	101,592,936 - 101,927,542 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	108,960,509 - 109,306,879 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	108,960,562 - 109,306,603 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	112,346,155 - 112,477,427 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	15	112,502,385 - 112,687,789 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	107,659,723 - 108,028,929 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	107,675,589 - 108,044,696 (+)	NCBI
Celera	15	98,401,724 - 98,738,731 (+)	NCBI		Celera
RH 3.4 Map	15	692.11	RGD
Cytogenetic Map	15	q25	NCBI

PCCA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	100,089,093 - 100,530,435 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	100,089,015 - 100,530,437 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	100,741,347 - 101,182,689 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	99,539,338 - 99,980,690 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	99,539,402 - 99,980,687	NCBI
Celera	13	81,585,804 - 82,027,260 (+)	NCBI		Celera
Cytogenetic Map	13	q32.3	NCBI
HuRef	13	81,336,606 - 81,778,760 (+)	NCBI		HuRef
CHM1_1	13	100,711,146 - 101,152,990 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	99,302,579 - 99,745,721 (+)	NCBI		T2T-CHM13v2.0

Pcca
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	122,721,822 - 123,127,372 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	122,771,736 - 123,128,512 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	122,484,365 - 122,889,944 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	122,534,324 - 122,891,100 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	122,933,550 - 123,289,166 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	121,669,524 - 122,025,008 (+)	NCBI		MGSCv36	mm8
Celera	14	121,094,262 - 121,448,288 (+)	NCBI		Celera
Cytogenetic Map	14	E5	NCBI
cM Map	14	65.99	NCBI

Pcca
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	10,317,640 - 10,661,496 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955404	10,317,640 - 10,719,148 (-)	NCBI	ChiLan1.0	ChiLan1.0

PCCA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	101,616,111 - 102,056,078 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	100,283,182 - 100,723,379 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	81,259,313 - 81,699,117 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	100,390,959 - 100,837,772 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	100,390,959 - 100,837,772 (+)	Ensembl	panpan1.1		panPan2

PCCA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	49,965,134 - 50,428,025 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	50,023,369 - 50,428,027 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	49,745,683 - 50,208,149 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	50,406,847 - 50,870,032 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	50,464,478 - 50,870,032 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	50,114,652 - 50,516,893 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	50,090,509 - 50,553,146 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	50,127,751 - 50,590,508 (+)	NCBI		UU_Cfam_GSD_1.0

Pcca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	185,393,912 - 185,784,766 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936472	10,164,642 - 10,501,878 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936472	10,167,387 - 10,501,824 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PCCA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	68,920,929 - 69,286,430 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	68,920,923 - 69,286,431 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	76,363,099 - 76,547,559 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCCA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	78,722,186 - 79,156,049 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	78,722,286 - 79,156,863 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666046	35,224,719 - 35,662,275 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pcca
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624793	10,691,224 - 11,100,853 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624793	10,691,224 - 11,099,905 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pcca
852 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	250
Count of miRNA genes:	135
Interacting mature miRNAs:	146
Transcripts:	ENSRNOT00000019144, ENSRNOT00000057429
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631655	Bp126	Blood pressure QTL 126	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	58156477	101769107	Rat
731177	Uae26	Urinary albumin excretion QTL 26	2.4	0.025	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	15	67588667	101769107	Rat
2300326	Plaw1	Placental weight QTL 1	15	0.005	placenta mass (VT:0004257)	placenta wet weight (CMO:0002088)	15	68327165	100062518	Rat
1641889	Colcr6	Colorectal carcinoma resistance QTL 6	2.9	0.0126	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	15	73690518	99794247	Rat
2317055	Aia10	Adjuvant induced arthritis QTL 10	3.41		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	15	75788062	101769107	Rat
1549844	Bss7	Bone structure and strength QTL 7	6.4		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	15	75788062	101769107	Rat
70155	Gcs1	Gastric cancer susceptibility QTL1	3.8		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	15	76306099	101769107	Rat

Markers in Region

D15Rat63

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	99,794,071 - 99,794,247 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	109,133,729 - 109,133,904	NCBI	Rnor6.0
Rnor_5.0	15	112,515,664 - 112,515,839	UniSTS	Rnor5.0
RGSC_v3.4	15	107,849,474 - 107,849,649	UniSTS	RGSC3.4
RGSC_v3.4	15	107,849,473 - 107,849,649	RGD	RGSC3.4
RGSC_v3.1	15	107,865,254 - 107,865,429	RGD
Celera	15	98,564,878 - 98,565,053	UniSTS
RH 3.4 Map	15	710.8	RGD
RH 3.4 Map	15	710.8	UniSTS
RH 2.0 Map	15	611.6	RGD
FHH x ACI Map	15	73.9699	RGD
Cytogenetic Map	15	q25	UniSTS

D15Got102

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	99,948,518 - 99,948,686 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	109,287,130 - 109,287,299	NCBI	Rnor6.0
Rnor_5.0	15	112,668,040 - 112,668,209	UniSTS	Rnor5.0
RGSC_v3.4	15	108,008,042 - 108,008,212	RGD	RGSC3.4
RGSC_v3.4	15	108,008,043 - 108,008,212	UniSTS	RGSC3.4
RGSC_v3.1	15	108,023,823 - 108,023,992	RGD
Celera	15	98,718,982 - 98,719,151	UniSTS
RH 3.4 Map	15	726.3	UniSTS
RH 3.4 Map	15	726.3	RGD
RH 2.0 Map	15	628.0	RGD
Cytogenetic Map	15	q25	UniSTS

RH94721

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	99,968,005 - 99,968,158 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	109,306,616 - 109,306,768	NCBI	Rnor6.0
Rnor_5.0	15	112,687,526 - 112,687,678	UniSTS	Rnor5.0
RGSC_v3.4	15	108,028,666 - 108,028,818	UniSTS	RGSC3.4
Celera	15	98,738,468 - 98,738,620	UniSTS
RH 3.4 Map	15	692.11	UniSTS
Cytogenetic Map	15	q25	UniSTS

RH144434

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	99,662,146 - 99,662,421 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	108,994,717 - 108,994,991	NCBI	Rnor6.0
Rnor_5.0	15	112,380,733 - 112,381,007	UniSTS	Rnor5.0
RGSC_v3.4	15	107,694,050 - 107,694,324	UniSTS	RGSC3.4
Celera	15	98,435,849 - 98,436,123	UniSTS
RH 3.4 Map	15	710.3	UniSTS
Cytogenetic Map	15	q25	UniSTS

BE107713

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	99,746,171 - 99,746,327 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	109,081,293 - 109,081,448	NCBI	Rnor6.0
Rnor_5.0	15	112,464,083 - 112,464,238	UniSTS	Rnor5.0
Celera	15	98,517,236 - 98,517,391	UniSTS
RH 3.4 Map	15	708.6	UniSTS
Cytogenetic Map	15	q25	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	15	41	1	4	70	35	34	11	1
Low					4		7	7	4		7		7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599802	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC123185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ191052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK228512	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK601565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO574538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CX570803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000077482 ⟹ ENSRNOP00000072844

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	99,627,986 - 99,968,266 (+)	Ensembl
Rnor_6.0 Ensembl	15	108,960,562 - 109,306,603 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000081906 ⟹ ENSRNOP00000073510

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	99,628,018 - 99,968,266 (+)	Ensembl
Rnor_6.0 Ensembl	15	108,960,562 - 109,306,603 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094922 ⟹ ENSRNOP00000082095

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	99,627,986 - 99,968,266 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000096028 ⟹ ENSRNOP00000087798

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	99,628,018 - 99,968,266 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097463 ⟹ ENSRNOP00000076923

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	99,627,994 - 99,968,266 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099022 ⟹ ENSRNOP00000082674

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	99,627,982 - 99,966,023 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100907 ⟹ ENSRNOP00000078501

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	99,627,986 - 99,968,266 (+)	Ensembl

RefSeq Acc Id:

NM_019330 ⟹ NP_062203

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	106,034,618 - 106,374,908 (+)	NCBI
mRatBN7.2	15	99,627,986 - 99,968,269 (+)	NCBI
Rnor_6.0	15	108,960,530 - 109,306,879 (+)	NCBI
Rnor_5.0	15	112,346,155 - 112,477,427 (+)	NCBI
Rnor_5.0	15	112,502,385 - 112,687,789 (+)	NCBI
RGSC_v3.4	15	107,659,723 - 108,028,929 (+)	RGD
Celera	15	98,401,724 - 98,738,731 (+)	RGD

Sequence:

show sequence

GTTCAGCGGCCAGCAAGTCGGCTGGGACGACAATGGCGGGGCTGTGGGTCAGGACAGTGGCACT
ATTGGCGGCCAGGCGGCATTGGCGGCGGTCCTCCCAGCAACTGCTGTGGACGCTGAAGCGTGCT
CCAGTCTATTCACAGCAATGCCTAGTGGTGTCCCGAAGTCTCAGTTCTGTGGAATATGAGCCTA
AAGAAAAAACTTTTGATAAAATTCTTATTGCTAACAGAGGAGAAATTGCTTGTAGGGTCATTAA
GACTTGCAGGAAGATGGGCATCAGGACAGTTGCCATCCACAGTGATGTTGATGCCAGCTCGGTT
CATGTGAAAATGGCGGATGAGGCTGTCTGTGTTGGCCCAGCTCCCACCAGTAAAAGCTACCTCA
ACATGGATGCCATCATGGAGGCCATTAAGAAAACCGGGGCCCAAGCTGTACACCCAGGTTATGG
ATTCCTGTCAGAAAACAAAGAGTTTGCAAAGTGTTTGGCAGCAGAAGATGTCACTTTCATTGGA
CCTGATACTCATGCTATTCAAGCCATGGGTGACAAGATAGAAAGCAAACTGTTAGCCAAGAGAG
CAAAGGTCAACACAATCCCTGGTTTTGATGGGGTACTAAAGGATGCAGATGAAGCCGTCAGAAT
TGCAAGGGAAATTGGCTACCCTGTGATGATCAAGGCCTCAGCAGGCGGTGGTGGGAAAGGCATG
CGCATCCCGTGGGATGACGAAGAGACCAGGGATGGCTTTAGATTTTCATCCCAGGAAGCTGCTT
CTAGTTTTGGTGATGATAGACTACTAATAGAAAAATTTATCGATAACCCTCGTCATATAGAAAT
CCAGGTTTTAGGGGATAAACATGGCAATGCTCTGTGGCTCAATGAGAGGGAGTGCTCGATCCAG
AGAAGAAACCAGAAGGTGGTAGAGGAGGCGCCGAGCATTTTTCTGGATCCTGAGACGCGCCGAG
CCATGGGAGAGCAGGCCGTGGCTTGGCCAAAAGCGGTGAAGTATTCTTCTGCTGGAACTGTGGA
ATTTCTTGTGGACTCCCAGAAGAATTTTTACTTCTTGGAGATGAATACAAGACTCCAGGTTGAA
CATCCTGTCACAGAGTGCATTACTGGCCTGGACTTAGTCCAAGAAATGATCCTGGTTGCTAAGG
GTTACCCACTCAGGCACAAGCAAGAGGATATTCCCATCAGTGGCTGGGCAGTTGAATGTCGGGT
TTATGCTGAGGACCCCTACAAGTCTTTCGGTTTACCGTCTATTGGGAGACTGTCTCAGTACCAA
GAGCCTATACATCTACCTGGTGTCCGAGTTGACAGTGGCATCCAACCAGGAAGTGACATCAGCA
TCTATTATGACCCTATGATTTCAAAACTAGTCACATATGGATCTGACAGAGCAGAAGCCCTGAA
GAGGATGGAAGATGCATTGGACAGTTATGTTATCCGGGGTGTTACACACAACATCCCACTGCTT
CGGGAGGTGATAATCAACACGCGTTTTGTGAAAGGGGACATCAGCACTAAGTTTCTCTCTGATG
TGTATCCTGATGGCTTCAAAGGGCACATGTTAACACCCAGTGAGAGAGACCAGTTATTGGCTAT
TGCATCATCCTTGTTTGTGGCATCCCAGCTACGAGCACAGCGCTTTCAAGAACATTCAAGAGTT
CCAGTTATAAGGCCAGATGTGGCTAAGTGGGAGCTCTCAGTAAAATTACATGATGAAGACCATA
CTGTTGTGGCATCCAACAACGGGCCAACATTTAACGTGGAAGTTGATGGCTCGAAACTAAATGT
GACCAGTACGTGGAACCTGGCCTCACCCTTATTGTCTGTCAACGTTGATGGCACTCAGAGGACT
GTGCAGTGTCTTTCTCGGGACGCAGGTGGAAACATGAGCATCCAGTTTCTTGGCACAGTGTACA
AAGTGCACATTTTAACCAAACTTGCTGCAGAACTGAACAAATTCATGCTTGAAAAAGTACCCAA
GGACACTAGCAGCACTCTGTGCTCCCCGATGCCTGGAGTGGTGGTGGCCGTTTCCGTCAAGCCT
GGAGACATGGTAGCAGAAGGTCAGGAAATCTGTGTGATTGAAGCTATGAAAATGCAGAACAGTA
TGACAGCTGGTAAAATGGGCAAGGTGAAACTGGTGCACTGCAAAGCTGGAGACACAGTTGGTGA
AGGAGACCTGCTCGTGGAGCTGGAATGAAGTACTTGTAGCCCTTCAGTCACCACTGCTCACTGC
TTTAATTAGCATTTCCATTATTCTCTAACCCTCAATTTGCTCAGGCGTTTACAGGAGCACTCTG
TGCAGCAGGTTCTACAGCATCGTATTTATTCCTCAGAAGAGGCAAAACCGACACTCTGCCAAAA
AAATCACCAATGGGAATTTTTATTGATATAAATACTTGTATATATGATTTGTACTTCTGCTGAG
ATTTCCCAGTGTCAAAATTAAATCAATAAAACCAAGCATTTGTCTAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039093664 ⟹ XP_038949592

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	106,034,586 - 106,374,908 (+)	NCBI
mRatBN7.2	15	99,627,955 - 99,968,269 (+)	NCBI

RefSeq Acc Id:

XM_063274647 ⟹ XP_063130717

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	106,034,586 - 106,374,908 (+)	NCBI

RefSeq Acc Id:

XM_063274648 ⟹ XP_063130718

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	106,034,586 - 106,374,908 (+)	NCBI

RefSeq Acc Id:

XM_063274649 ⟹ XP_063130719

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	106,034,586 - 106,374,908 (+)	NCBI

RefSeq Acc Id:

XM_063274650 ⟹ XP_063130720

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	106,034,586 - 106,374,908 (+)	NCBI

RefSeq Acc Id:

XM_063274651 ⟹ XP_063130721

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	106,062,009 - 106,374,908 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_062203	(Get FASTA)	NCBI Sequence Viewer
	XP_038949592	(Get FASTA)	NCBI Sequence Viewer
	XP_063130717	(Get FASTA)	NCBI Sequence Viewer
	XP_063130718	(Get FASTA)	NCBI Sequence Viewer
	XP_063130719	(Get FASTA)	NCBI Sequence Viewer
	XP_063130720	(Get FASTA)	NCBI Sequence Viewer
	XP_063130721	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072844.2
	ENSRNOP00000073510.2
	ENSRNOP00000076923.1
	ENSRNOP00000078501.1
	ENSRNOP00000082095
	ENSRNOP00000082095.1
	ENSRNOP00000082674.1
	ENSRNOP00000087798
	ENSRNOP00000087798.1
GenBank Protein	P14882	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_062203 ⟸ NM_019330

- UniProtKB:

A0A8I5ZL37 (UniProtKB/TrEMBL), A6HUM3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGLWVRTVALLAARRHWRRSSQQLLWTLKRAPVYSQQCLVVSRSLSSVEYEPKEKTFDKILIA
NRGEIACRVIKTCRKMGIRTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKK
TGAQAVHPGYGFLSENKEFAKCLAAEDVTFIGPDTHAIQAMGDKIESKLLAKRAKVNTIPGFDG
VLKDADEAVRIAREIGYPVMIKASAGGGGKGMRIPWDDEETRDGFRFSSQEAASSFGDDRLLIE
KFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDPETRRAMGEQAVAWPK
AVKYSSAGTVEFLVDSQKNFYFLEMNTRLQVEHPVTECITGLDLVQEMILVAKGYPLRHKQEDI
PISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDSGIQPGSDISIYYDPMISKLV
TYGSDRAEALKRMEDALDSYVIRGVTHNIPLLREVIINTRFVKGDISTKFLSDVYPDGFKGHML
TPSERDQLLAIASSLFVASQLRAQRFQEHSRVPVIRPDVAKWELSVKLHDEDHTVVASNNGPTF
NVEVDGSKLNVTSTWNLASPLLSVNVDGTQRTVQCLSRDAGGNMSIQFLGTVYKVHILTKLAAE
LNKFMLEKVPKDTSSTLCSPMPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKL
VHCKAGDTVGEGDLLVELE

hide sequence

RefSeq Acc Id:

ENSRNOP00000072844 ⟸ ENSRNOT00000077482

RefSeq Acc Id:

ENSRNOP00000073510 ⟸ ENSRNOT00000081906

RefSeq Acc Id:	XP_038949592 ⟸ XM_039093664
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I5ZL37 (UniProtKB/TrEMBL), A0A8I5ZWE0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000082095 ⟸ ENSRNOT00000094922

RefSeq Acc Id:

ENSRNOP00000082674 ⟸ ENSRNOT00000099022

RefSeq Acc Id:

ENSRNOP00000087798 ⟸ ENSRNOT00000096028

RefSeq Acc Id:

ENSRNOP00000078501 ⟸ ENSRNOT00000100907

RefSeq Acc Id:

ENSRNOP00000076923 ⟸ ENSRNOT00000097463

RefSeq Acc Id:	XP_063130717 ⟸ XM_063274647
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063130718 ⟸ XM_063274648
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063130719 ⟸ XM_063274649
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063130720 ⟸ XM_063274650
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063130721 ⟸ XM_063274651
- Peptide Label:	isoform X6

Protein Domains

ATP-grasp Biotin carboxylation Biotinyl-binding Lipoyl-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P14882-F1-model_v2	AlphaFold	P14882	1-737	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699893

Promoter ID:

EPDNEW_R10408

Type:

single initiation site

Name:

AC123185_1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	108,956,394 - 108,956,454	EPDNEW

RGD ID:

13699885

Promoter ID:

EPDNEW_R10409

Type:

initiation region

Name:

Pcca_1

Description:

propionyl-CoA carboxylase alpha subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	108,960,526 - 108,960,586	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3264	AgrOrtholog
BioCyc Gene	G2FUF-12336	BioCyc
BioCyc Pathway	PROPIONMET-PWY [propanoyl CoA degradation I]	BioCyc
BioCyc Pathway Image	PROPIONMET-PWY	BioCyc
Ensembl Genes	ENSRNOG00000057042	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000077482.2	UniProtKB/TrEMBL
	ENSRNOT00000081906.2	UniProtKB/TrEMBL
	ENSRNOT00000094922.1	UniProtKB/TrEMBL
	ENSRNOT00000096028	ENTREZGENE
	ENSRNOT00000096028.1	UniProtKB/TrEMBL
	ENSRNOT00000097463.1	UniProtKB/TrEMBL
	ENSRNOT00000099022.1	UniProtKB/TrEMBL
	ENSRNOT00000100907.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.100	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.1490.20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.700.30	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ATP-grasp fold, B domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	ATP-grasp	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ATP_grasp_subdomain_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BC-like_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Biotin_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Biotin_carboxylation_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Biotin_COase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Biotin_lipoyl	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CbamoylP_synth_lsu-like_ATP-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PCC_BT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PreATP-grasp_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Rudment_hybrid_motif	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Single_hybrid_motif	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:687008	UniProtKB/Swiss-Prot
NCBI Gene	Pcca	ENTREZGENE
PANTHER	CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Biotin_carb_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Biotin_carb_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Biotin_lipoyl	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CPSase_L_D2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PCC_BT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pcca	PhenoGen
PROSITE	ATP_GRASP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BIOTIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BIOTINYL_LIPOYL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CPSASE_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CPSASE_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PS50979	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000057042	RatGTEx
SMART	Biotin_carb_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glutathione synthetase ATP-binding domain-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF51230	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF51246	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52440	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC205059
UniProt	A0A0G2K401_RAT	UniProtKB/TrEMBL
	A0A0G2K5P9_RAT	UniProtKB/TrEMBL
	A0A8I5YBZ6_RAT	UniProtKB/TrEMBL
	A0A8I5ZL37	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZVD4_RAT	UniProtKB/TrEMBL
	A0A8I5ZWE0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A8G9_RAT	UniProtKB/TrEMBL
	A6HUM3	ENTREZGENE, UniProtKB/TrEMBL
	P14882	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-04	Pcca	propionyl-CoA carboxylase subunit alpha	Pcca	propionyl-CoA carboxylase alpha subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-11-20	Pcca	propionyl-CoA carboxylase alpha subunit	Pcca	propionyl CoA carboxylase, alpha polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-04-01	Pcca	propionyl CoA carboxylase, alpha polypeptide	Pcca	propionyl-coenzyme A carboxylase, alpha polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-05	Pcca	propionyl-coenzyme A carboxylase, alpha polypeptide	LOC687008	similar to Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (PCCase alpha subunit) (Propanoyl-CoA:carbon dioxide ligase alpha subunit)	Data merged from RGD:1590160	737654	APPROVED
2006-11-20	LOC687008	similar to Propionyl-CoA carboxylase alpha chain, mitochondrial precursor (PCCase alpha subunit) (Propanoyl-CoA:carbon dioxide ligase alpha subunit)			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-06-10	Pcca	Propionyl Coenzyme A carboxylase, alpha polypeptide			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_protein	may contain a biotinylated lysine residue	633579

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways